Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gina L Zoratti"'
Autor:
Julie L Boerner, Nicole Nechiporchik, Kelly L Mueller, Lisa Polin, Lance Heilbrun, Scott A Boerner, Gina L Zoratti, Karri Stark, Patricia M LoRusso, Angelika Burger
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119614 (2015)
Patients with metastatic triple-negative breast cancer (TNBC) have a poor prognosis. New approaches for the treatment of TNBC are needed to improve patient survival. The concept of synthetic lethality, brought about by inactivating complementary DNA
Externí odkaz:
https://doaj.org/article/4870bf194f7140bdb5a6912096e85e25
Autor:
Gregory S Miller, Gina L Zoratti, Andrew S Murray, Christopher Bergum, Lauren M Tanabe, Karin List
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87675 (2014)
Over the last two decades, cell surface proteases belonging to the type II transmembrane serine protease (TTSP) family have emerged as important enzymes in the mammalian degradome, playing critical roles in epithelial biology, regulation of metabolic
Externí odkaz:
https://doaj.org/article/42fd4f96e87b48a385f2ad6cbe14c057
Autor:
Lauren M. Tanabe, Michael J. Duhaime, Éloïc Colombo, Karin List, Michael D. Johnson, Chen-Yong Lin, Thomas E. Hyland, Julie L. Boerner, Julie E. Lang, Richard Leduc, Gina L. Zoratti, Eric Marsault
Publikováno v:
Oncotarget, vol 7, iss 36
Oncotarget
Oncotarget
The poor prognosis for patients with inflammatory breast cancer (IBC) compared to patients with other types of breast cancers emphasizes the need to better understand the molecular underpinnings of this disease with the goal of developing effective t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedacb3658d404f81ba6582d38525e8f
https://escholarship.org/uc/item/8b9513qt
https://escholarship.org/uc/item/8b9513qt
Autor:
Michael E. Silverman, Khaliph O. Page, Fausto A. Varela, Andrew S. Murray, Karin List, Michael J. Duhaime, Gina L. Zoratti
Publikováno v:
Journal of Cellular Physiology
Cancer progression is accompanied by increased levels of extracellular proteases that are capable of remodeling the extracellular matrix, as well as cleaving and activating growth factors and receptors that are involved in pro-cancerous signaling pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebbb622518c8e8d452ffd465c2693ca
https://europepmc.org/articles/PMC4933652/
https://europepmc.org/articles/PMC4933652/
Publikováno v:
Matrix Proteases in Health and Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2dc2185871ff0c388466f9a4394f6a
https://doi.org/10.1002/9783527649327.ch5
https://doi.org/10.1002/9783527649327.ch5
Autor:
Fausto A. Varela, Andrew S. Murray, Lauren M. Tanabe, Alfredo A. Molinolo, Eric Marsault, Julie L. Boerner, Karin List, Richard Leduc, Éloïc Colombo, Christopher Bergum, Gina L. Zoratti, Julie E. Lang
Publikováno v:
Nature communications, vol 6, iss 1
Nature communications
Nature communications
Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years because of its consistent dysregulation in human epithelial tumours, including breast cancer. Mice with reduced levels of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04ebac749c99613273971d6ecdeb40
https://escholarship.org/uc/item/9g60f5zr
https://escholarship.org/uc/item/9g60f5zr
Autor:
Lauren M. Tanabe, Andrew S. Murray, Christopher Bergum, Karin List, Gina L. Zoratti, Gregory S. Miller
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87675 (2014)
PLoS ONE
PLoS ONE
Over the last two decades, cell surface proteases belonging to the type II transmembrane serine protease (TTSP) family have emerged as important enzymes in the mammalian degradome, playing critical roles in epithelial biology, regulation of metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc1e9f14423d4e3943007b49aaeadef
http://europepmc.org/articles/PMC3912027?pdf=render
http://europepmc.org/articles/PMC3912027?pdf=render
Autor:
Kelly L. Mueller, Gina L. Zoratti, Charlotte Kuperwasser, Julie M. Madden, Karin List, Julie L. Boerner
Publikováno v:
Breast Cancer Research : BCR
Introduction Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have shown clinical efficacy in lung, colon, and pancreatic cancers. In lung cancer, resistance to EGFR TKIs correlates with amplification of the hepatocyte growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd66b371471ced9fd463d463f9c4bc4
https://pubmed.ncbi.nlm.nih.gov/22788954
https://pubmed.ncbi.nlm.nih.gov/22788954
Publikováno v:
Journal of cellular physiology. 227(4)
Breast cancer tumorigenesis is accompanied by increased levels of extracellular proteases that are capable of remodeling the extracellular matrix as well as cleaving and activating growth factors and signaling receptors that are critically involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2804abdf9d21605838c362c12863fccc
https://pubmed.ncbi.nlm.nih.gov/21678412
https://pubmed.ncbi.nlm.nih.gov/21678412
Publikováno v:
Cancer Research. 73:5066-5066
Historically proteases have been associated with tumor progression and metastasis through degradation of the basement membrane. In recent years these enzymes have also been shown to play key roles in the activation of growth factors and cytokines, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098d898890d3398d00ed7956523ca3ef
https://doi.org/10.1158/1538-7445.am2013-5066
https://doi.org/10.1158/1538-7445.am2013-5066