Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gina Deiter"'
Autor:
Jennifer L Steiner, Anne M Pruznak, Gina Deiter, Maithili Navaratnarajah, Lydia Kutzler, Scot R Kimball, Charles H Lang
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99582 (2014)
Sepsis decreases skeletal muscle protein synthesis in part by impairing mTOR activity and the subsequent phosphorylation of 4E-BP1 and S6K1 thereby controlling translation initiation; however, the relative importance of changes in these two downstrea
Externí odkaz:
https://doaj.org/article/cc23a4fbb4b94a558fbeb6766d0c17fe
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 312:R146-R156
Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial hy
Publikováno v:
Exp Neurol
Dramatic impairment of gastrointestinal (GI) function accompanies high-thoracic spinal cord injury (T3-SCI). The vagus nerve contains mechano- and chemosensory fibers as well as the motor fibers necessary for the central nervous system (CNS) control
Publikováno v:
Journal of Clinical Oncology. 36:e17508-e17508
e17508Background: After demonstrating therapeutic potential of anti-HPV E6 monoclonal antibody (mAb C1P5) compared to isotype control mAb (MopC21) in a murine model of HPV cervical cancer, we sough...
Publikováno v:
Alcoholism: Clinical and Experimental Research. 32:43-51
Background: Chronic alcohol administration impairs protein synthesis ultimately causing a loss of proteins in cardiac muscle. Inhibition of protein synthesis resides in the process of mRNA translation. The present set of experiments were designed to
Acute alcohol intoxication enhances myocardial eIF4G phosphorylation despite reducing mTOR signaling
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H121-H128
Acute alcohol intoxication impairs myocardial protein synthesis in rats, secondary to a diminished mRNA translational efficiency. Decreased mRNA translational efficiency occurs through altered regulation of peptide chain initiation. The purpose of th
Publikováno v:
Shock. 22:548-554
Sepsis induces weight loss and the loss of skeletal muscle proteins, in part through an inhibition of protein synthesis secondary to an inhibition of the key steps controlling mRNA translation in skeletal muscle. We have previously shown that sepsis
Publikováno v:
Alcoholism: Clinical & Experimental Research. 26:1794-1802
Background Acute and chronic alcohol administration diminishes rates of protein synthesis in a variety of tissues including skeletal muscle, heart, and liver, through a diminished translational efficiency rather than a reduction in the number of ribo
Autor:
Charles H. Lang, Maithili Navaratnarajah, Anne M. Pruznak, Gina Deiter, Scot R. Kimball, Lydia Kutzler, Jennifer L. Steiner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e99582 (2014)
PLoS ONE, Vol 9, Iss 6, p e99582 (2014)
Sepsis decreases skeletal muscle protein synthesis in part by impairing mTOR activity and the subsequent phosphorylation of 4E-BP1 and S6K1 thereby controlling translation initiation; however, the relative importance of changes in these two downstrea
Publikováno v:
The FASEB Journal. 28