Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gina, Eagle"'
Autor:
Fernando Carvalho Neuenschwander, Ofra Barnett-Griness, Stefania Piconi, Yasmin Maor, Eduardo Sprinz, Nimer Assy, Oleg Khmelnitskiy, Nikita V. Lomakin, Boris Mikhailovich Goloshchekin, Ewelina Nahorecka, Adilson Joaquim Westheimer Calvacante, Anastasia Ivanova, Sergey Vladimirovich Zhuravel, Galina Yurevna Trufanova, Stefano Bonora, Amer Saffoury, Ami Mayo, Yury G. Shvarts, Giuliano Rizzardini, Rogerio Sobroza de Mello, Janaina Pilau, Alexey Klinov, Benjamin Valente-Acosta, Oleg Olegovich Burlaka, Natalia Bakhtina, Maskit Bar-Meir, Ivan Nikolaevich Shishimorov, Jose Oñate-Gutierrez, Cristian Iván García Rincón, Tatiana Ivanovna Martynenko, Ludhmila Abrahão Hajjar, Ana Carolina Nazare de Mendonca Procopio, Krzysztof Simon, Walter Gabriel Chaves Santiago, Adam Fronczak, Conrado Roberto Hoffmann Filho, Osama Hussein, Vladimir Aleksandrovich Martynov, Guido Chichino, Piotr Blewaska, Jacek Wroblewski, Sergio Saul Irizar Santana, Andres Felipe Ocampo Agudelo, Adam Barczyk, Rachael lask Gerlach, Eppie Campbell, Aida Bibliowicz, Reza Fathi, Patricia Anderson, Gilead Raday, Michal Klein, Clara Fehrmann, Gina Eagle, Vered Katz Ben-Yair, Mark L. Levitt
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1767 (2024)
Once a patient has been diagnosed with severe COVID-19 pneumonia, treatment options have limited effectiveness. Opaganib is an oral treatment under investigation being evaluated for treatment of hospitalized patients with severe COVID-19 pneumonia. A
Externí odkaz:
https://doaj.org/article/4abee192ba974c30b03ccb75515ad1f3
Effect of Opaganib on Supplemental Oxygen and Mortality in Patients with Severe SARS-CoV-2 Pneumonia
Autor:
Fernando Carvalho Neuenschwander, Ofra Barnett-Griness, Stefania Piconi, Yasmin Maor, Eduardo Sprinz, Nimer Assy, Oleg Khmelnitskiy, Nikita Lomakin, Boris Mikhailovich Goloshchekin, Ewelina Nahorecka, Adilson Joaquim Westheimer Calvacante, Anastasia Ivanova, Sergey Vladimirovich Zhuravel, Galina Yurevna Trufanova, Stefano Bonora, Amer Saffoury, Ami Mayo, Yury Shvarts, Giuliano Rizzardini, Rogerio Sobroza de Mello, Janaina Pilau, Alexey Klinov, Benjamin Valente-Acosta, Oleg Olegovich Burlaka, Natalia Bakhtina, Maskit Bar-Meir, Ivan Nikolaevich Shishimorov, Jose Oñate-Gutierrez, Cristian Ivan Garcia Rincon, Tatiana Ivanovna Martynenko, Ludhmila Abrahão Hajjar, Ana Carolina Nazare de Mendonca Procopio, Krzystof Simon, Walter Gabriel Chaves Santiago, Adam Fronczak, Conrado Roberto Hoffmann Filho, Osama Hussein, Vladimir Aleksandrovich Martynov, Guido Chichino, Piotr Blewaska, Jacek Wroblewski, Sergio Saul Irizar Santana, Andres Felipe Ocampo Agudelo, Adam Barczyk, Rachael L. Gerlach, Eppie Campbell, Aida Bibliowicz, Reza Fathi, Patricia Anderson, Gilead Raday, Michal Klein, Clara Fehrmann, Gina Eagle, Vered Katz Ben-Yair, Mark L. Levitt
RationaleThere are few treatment options for severe COVID-19 pneumonia. Opaganib is an oral treatment under investigation.ObjectiveEvaluate opaganib treatment in hospitalized patients with severe COVID-19 pneumonia.MethodsA randomized, placebo-contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac5a8655eb260c38557cc88d09eaf63c
https://doi.org/10.1101/2022.06.12.22276088
https://doi.org/10.1101/2022.06.12.22276088
Autor:
Kevin L, Winthrop, Alan W, Skolnick, Adnan M, Rafiq, Scott H, Beegle, Julian, Suszanski, Guenther, Koehne, Ofra, Barnett-Griness, Aida, Bibliowicz, Reza, Fathi, Patricia, Anderson, Gilead, Raday, Gina, Eagle, Vered Katz, Ben-Yair, Harold S, Minkowitz, Mark L, Levitt, Michael S, Gordon
Publikováno v:
Open Forum Infectious Diseases. 9
Background Opaganib, an oral sphingosine kinase-2 inhibitor with antiviral and anti-inflammatory properties, was shown to inhibit severe acute respiratory syndrome coronavirus 2 replication in vitro. We thus considered that opaganib could be benefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f33875e2beb27da2f8d2f5e869c44f
https://doi.org/10.1093/ofid/ofac232
https://doi.org/10.1093/ofid/ofac232
Autor:
Scott Beegle, Alan W Skolnick, Mark L. Levitt, Michael S Gordon, Patricia Anderson, Harold S Minkowitz, Gina Eagle, Guenther Koehne, Gilead Raday, Kevin L. Winthrop, Adnan Rafiq, Reza Fathi, Aida Bibliowicz, Ofra Barnett-Griness, Vered Katz Ben-Yair, Julian Suszanski
BackgroundOpaganib, an oral sphingosine kinase-2 inhibitor with antiviral and anti-inflammatory properties, was shown to inhibit SARS-CoV-2 replication in vitro. We thus considered that opaganib could be beneficial for moderate to severe COVID-19 pne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11367e9baa18250ae680554587c233e6
https://doi.org/10.1101/2021.08.23.21262464
https://doi.org/10.1101/2021.08.23.21262464
Autor:
Ping Wang, Mehdi Mirsaeidi, Theodore K. Marras, Quanwu Zhang, Raymond Zhang, Edward D. Chan, Christopher Vinnard, Gina Eagle
Publikováno v:
Journal of Medical Economics. 22:1126-1133
Background: The prevalence of nontuberculous mycobacterial lung disease (NTMLD) in the US has increased; however, data characterizing the associated healthcare utilization and expenditure a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c429ef175ba5c3db6dfb56d936ea5d8
https://doi.org/10.1080/13696998.2019.1620243
https://doi.org/10.1080/13696998.2019.1620243
Autor:
Jean Paty, Karol Knoop, Evan S. Dellon, Stella Karantzoulis, James Nezamis, Ashley F. Slagle, Nicole Sparling, Gina Eagle
Publikováno v:
American Journal of Gastroenterology. 116:S205-S206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7c54fbe474959453c597cebaa1a102
https://doi.org/10.14309/01.ajg.0000774332.55866.3c
https://doi.org/10.14309/01.ajg.0000774332.55866.3c
Autor:
Gary W. Falk, Gail M. Comer, Karol Knoop, Alfredo J. Lucendo, Evan S. Dellon, Ikuo Hirano, Christop Schlag, James Nezamis, Gina Eagle, Alain M. Schoepfer
Publikováno v:
American Journal of Gastroenterology. 116:S152-S153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396e10fb5f24ca3dc310b4e28eecd7d1
https://doi.org/10.14309/01.ajg.0000773884.45924.08
https://doi.org/10.14309/01.ajg.0000773884.45924.08
Autor:
Quanwu Zhang, Theodore K. Marras, Jennifer Adjemian, Engels Chou, Raymond Zhang, Kenneth N. Olivier, Christopher Vinnard, Gina Eagle, Keith W. Hamilton
Publikováno v:
Respiratory Medicine. 145:80-88
RATIONALE: The risk of all-cause mortality of nontuberculous mycobacterial lung disease (NTMLD) in the United States (US) population is not well established. OBJECTIVES: This study aims to assess the public health burden of NTMLD in the US by compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dd3fd38ee3f12edd29a7791f43dd07
https://doi.org/10.1016/j.rmed.2018.10.022
https://doi.org/10.1016/j.rmed.2018.10.022
Autor:
Mary Leuchars, Mehdi Mirsaeidi, Quanwu Zhang, Theodore K. Marras, Raymond Zhang, Gina Eagle, Engels Chou
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 24:964-974
Nontuberculous mycobacterial lung disease (NTMLD) is an important public health concern that has been increasing in prevalence.To (a) describe hospitalizations and health care expenditures among patients with newly diagnosed NTMLD and (b) estimate at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f96ab86c2ffc893ab099fd712ec9b8
https://doi.org/10.18553/jmcp.2018.18122
https://doi.org/10.18553/jmcp.2018.18122
Autor:
Ralph Turner, Evan S. Dellon, Nicole Sparling, James Nezamis, Joy Whitsett, Jeffrey M. Rohay, Jean Paty, Karol Knoop, Ikuo Hirano, Gina Eagle
Publikováno v:
American Journal of Gastroenterology. 116:S203-S203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc997d05a2ab79518df62be4f26f819b
https://doi.org/10.14309/01.ajg.0000774304.21136.36
https://doi.org/10.14309/01.ajg.0000774304.21136.36