Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gin-Fu Chen"'
Autor:
Norifumi Urao, Varadarajan Sudhahar, Seok-Jo Kim, Gin-Fu Chen, Ronald D McKinney, Georg Kojda, Tohru Fukai, Masuko Ushio-Fukai
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57618 (2013)
BACKGROUND:Reactive oxygen species (ROS) play an important role in angiogenesis in endothelial cells (ECs) in vitro and neovascularization in vivo. However, little is known about the role of endogenous vascular hydrogen peroxide (H2O2) in postnatal n
Externí odkaz:
https://doaj.org/article/90dc05f3453c46418fbf492c1e68001a
Autor:
Zhongjie Sun, Peter Gin Fu Chen
Publikováno v:
Human Gene Therapy. 28:190-199
Cold temperatures are associated with increased prevalence of hypertension. Cold exposure increases endothelin-1 (ET1) production. The purpose of this study is to determine whether upregulation of ET1 contributes to cold-induced hypertension (CIH). I
Autor:
Gin-Fu Chen1, Sudhahar, Varadarajan1,2,3 mfukai@uic.edu, Seock-Won Youn2,4, Das, Archita2, Jaehyung Cho4, Tetsuro Kamiya1,2, Norifumi Urao4, McKinney, Ronald D.1,3,4, Surenkhuu, Bayasgalan1, Takao Hamakubo5, Hiroko Iwanari5, Senlin Li6, Christman, John W.7, Shantikumar, Saran8, Angelini, Gianni D.8,9, Emanueli, Costanza8,9, Masuko Ushio-Fukai2,4, Tohru Fukai1,2,3,4 tfukai@uic.edu
Publikováno v:
Scientific Reports. 10/9/2015, p1-20. 20p.
Autor:
Jones, Hazel C.1 hjones@ufl.edu, Gin-Fu Chen1, Yehia, Baligh R.1, Carter, Barbara J.1, Akins, Elizabeth J.1, Wolpin, Logan C.1
Publikováno v:
Mammalian Genome. Apr2005, Vol. 16 Issue 4, p251-261. 11p.
Autor:
Varadarajan Sudhahar, Ha Won Kim, Stefan Vogt, Junghun Kweon, Tohru Fukai, Archita Das, Bayasgalan Surenkhuu, Masuko Ushio-Fukai, Lydia Finney, Jay Yang, Gin Fu Chen, Seock Won Youn
Publikováno v:
Scientific Reports
Copper (Cu), an essential nutrient, promotes wound healing, however, target of Cu action and underlying mechanisms remain elusive. Cu chaperone Antioxidant-1 (Atox1) in the cytosol supplies Cu to the secretory enzymes such as lysyl oxidase (LOX), whi
Autor:
Tohru Fukai, Masuko Ushio-Fukai, Varadarajan Sudhahar, Takashi Kohno, Lydia Finney, Gin Fu Chen, Ha Won Kim, Stefan Vogt, Ronald D McKinney, Kiyoshi Ozumi
Publikováno v:
Hypertension. 60:476-486
Extracellular superoxide dismutase (SOD3) is a secretory copper enzyme involved in protecting angiotensin II (Ang II)–induced hypertension. We found previously that Ang II upregulates SOD3 expression and activity as a counterregulatory mechanism; h
Autor:
Archita Das, Sudhahar Varadarajan, Gin-Fu Chen, Bayasgalan Surenkhuu, Jun Tian, Masuko Ushio-Fukai, Tohru Fukai
Publikováno v:
Circulation. 132
Tumor necrosis factor-TNFα plays a key role in atherosclerosis via NADPH oxidase-derived reactive oxygen species (ROS) and its downstream redox-sensitive inflammatory responses. Copper (Cu) has been implicated in atherosclerosis and inflammation wit
Autor:
Lydia Finney, Seock Won Youn, Tohru Fukai, Gin-Fu Chen, Archita Das, Ha Won Kim, Jay Yang, Masuko Ushio-Fukai, Sudhahar Varadarajan
Publikováno v:
Circulation. 132
Copper (Cu) facilitates wound healing and angiogenesis with unknown mechanism. Bioavailability of Cu is controlled by transport-proteins, including cytosolic Cu-chaperone Atox1, which is required for activation of secretory Cu enzymes. Atox1 also fun
Autor:
Gin Fu Chen, Jennifer M. Sasser, László Wagner, Natasha C. Moningka, Sergey Zharikov, Chris Baylis
Publikováno v:
Nephrology Dialysis Transplantation. 25:3518-3525
Background. The fawn-hooded hypertensive (FHH) rat develops spontaneous glomerulosclerosis that is ameliorated by inhibition of the angiotensin II type 1 receptor (AT1). Since kidney damage is associated with nitric oxide (NO) deficiency, we investig
Autor:
Gin-Fu Chen, Chris Baylis
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F95-F102
The kidney is a major site of arginine synthesis where citrulline is converted to arginine via argininosuccinate synthase (ASS) and lyase (ASL). The rate-limiting step in arginine synthesis by the normal kidney is the rate of citrulline delivery and