Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Ginés M. Salido"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7641 (2020)
Progesterone receptor membrane component 1 (PGRMC1) has been shown to regulate some cancer hallmarks. Progesterone (P4) evokes intracellular calcium (Ca2+) changes in the triple-negative breast cancer cell lines (MDA-MB-231, MDA-MB-468, and BT-20) an
Externí odkaz:
https://doaj.org/article/f4422be0b0ae45fca271e3139476d201
Autor:
Carlos Cantonero, Jose Sánchez-Collado, Jose J. Lopez, Ginés M. Salido, Juan A. Rosado, Pedro C. Redondo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3315 (2020)
Arachidonic acid (AA) is a phospholipase A2 metabolite that has been reported to mediate a plethora of cellular mechanisms involved in healthy and pathological states such as platelet aggregation, lymphocyte activation, and tissue inflammation. AA ha
Externí odkaz:
https://doaj.org/article/0f93b48c37c54e618e5c3de1354d4ed2
Autor:
Jose J. Lopez, Isaac Jardin, Jose Sanchez-Collado, Ginés M. Salido, Tarik Smani, Juan A. Rosado
Publikováno v:
Cells, Vol 9, Iss 1, p 126 (2020)
Transient receptor potential (TRP) proteins form non-selective Ca2+ permeable channels that contribute to the modulation of a number of physiological functions in a variety of cell types. Since the identification of TRP proteins in Drosophila, it is
Externí odkaz:
https://doaj.org/article/b819076ab38b44a8a79c0834af9b1429
Autor:
Isaac Jardín, José J. López, Raquel Diez, José Sánchez-Collado, Carlos Cantonero, Letizia Albarrán, Geoffrey E. Woodard, Pedro C. Redondo, Ginés M. Salido, Tarik Smani, Juan A. Rosado
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
According to the International Association for the Study of Pain (IASP) pain is characterized as an “unpleasant sensory and emotional experience associated with actual or potential tissue damage”. The TRP super-family, compressing up to 28 isofor
Externí odkaz:
https://doaj.org/article/4d32a674e4e14723a9a41d5307330727
Autor:
Lucia Gonzalez-Gutierrez, Isaac Jardin, Ginés M. Salido, Juan A. Rosado, Jose J. Lopez, Carlos Cantonero, Jose Sanchez-Collado
Publikováno v:
Biochemical Journal. 477:3183-3197
TRPC6 forms non-selective cation channels activated by a variety of stimuli that are involved in a wide number of cellular functions. In estrogen receptor-positive (ER+) breast cancer cells, the store-operated Ca2+ entry has been reported to be depen
Autor:
María Prado Míguez, Diego Lopez, Antonio González, Matias Estaras, Alfredo Garcia, Daniel Vara, Remigio Martínez, Mario Estévez, Gerardo Blanco, Marcos Pérez-López, Jose M. Mateos, Miguel Fernandez-Bermejo, Ginés M. Salido, Salomé Martínez-Morcillo, V. Roncero
Publikováno v:
Biology of the Cell. 112:280-299
Background information Pancreatic stellate cells play a key role in the fibrosis that develops in diseases such as pancreatic cancer. In the growing tumour, a hypoxia condition develops under which cancer cells are able to proliferate. The growth of
Autor:
Miguel Fernandez-Bermejo, Ana M. Marchena, Jose M. Mateos, Antonio González, Matias Estaras, V. Roncero, Daniel Vara, Ginés M. Salido
Publikováno v:
Journal of Applied Toxicology. 40:1554-1565
In this study, we have examined the effects of luzindole, a melatonin receptor-antagonist, on cultured pancreatic stellate cells. Intracellular free-Ca2+ concentration, production of reactive oxygen species (ROS), activation of mitogen-activated prot
Autor:
Carlos Cantonero, M.A. Gonzalez-Nuñez, Jose J. Lopez, Ginés M. Salido, Jose Sanchez-Collado, Isaac Jardin, Juan A. Rosado
Publikováno v:
Cell Calcium. 80:1-7
Ca2+ channels play an important role in the development of different types of cancer, and considerable progress has been made to understand the pathophysiological mechanisms underlying the role of Ca2+ influx in the development of different cancer ha
Autor:
Ginés M. Salido, Juan Ortega-Vidal, Joaquín Altarejos, M. El Haouari, Jose J. Lopez, Raquel Diez-Bello, Isaac Jardin, Sofía Salido, Juan A. Rosado
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:474-485
Triple negative breast cancer is an aggressive type of cancer that does not respond to hormonal therapy and current therapeutic strategies are accompanied by side effects due to cytotoxic actions on normal tissues. Therefore, there is a need for the
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7641, p 7641 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7641, p 7641 (2020)
Progesterone receptor membrane component 1 (PGRMC1) has been shown to regulate some cancer hallmarks. Progesterone (P4) evokes intracellular calcium (Ca2+) changes in the triple-negative breast cancer cell lines (MDA-MB-231, MDA-MB-468, and BT-20) an