Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gim Hwa Tan"'
Autor:
Gim Hwa Tan, Sheng Chun Chang, Richie Soong, Mohd Feroz Mohd Omar, Daniel Q. Huang, Min Ji Han, Benny Tang, Bhaskar Bhattacharya, Sarah Hong Hui Low, Yock Young Dan, Sanamerjit Singh, Joey Sze Yun Lim
Publikováno v:
Oncotarget
The native hepatocellular cancer (HCC) microenvironment is characterized by more hypoxic, hypoglycemic, and acidic conditions than those used in standard cell culture. This study aimed to investigate whether HCC cells cultured in more native conditio
Autor:
Bhaskar Bhattacharya, Mounia Beloueche-Babari, Richie Soong, Gim Hwa Tan, Mohd Feroz Mohd Omar, Min Ji Han, Ross A. Soo, King Xin Koh, Sarah Hong Hui Low, Barry Iacopetta
Publikováno v:
Oncotarget
Acquired resistance (AQR) to drug treatment occurs frequently in cancer patients and remains an impediment to successful therapy. The aim of this study was to gain insight into how AQR arises following the application of PI3K/mTOR inhibitors. H1975 l
Autor:
Sarah Hong Hui Low, Benny Tang, Gim Hwa Tan, Richie Soong, Mohd Feroz Mohd Omar, Bhaskar Bhattacharya, Sheng Chun Chang
Publikováno v:
Cancer Research. 77:165-165
Background: Hepatocellular carcinoma (HCC) is characterized by hypoxia, hypoglycemia and lactic acidosis within the microenvironment due a highly glycolytic phenotype. However, routine culture conditions of HCC cells employ supra-physiological glucos
Autor:
Gim Hwa Tan, Richie Soong, Sanamerjit S. Mann, Barry E. McGuinness, Alan Wise, Sarah Hh Low, Phillip M. Cowley, Sarah C. Trewick, Min Ji Han, Bhaskar Bhattacharya
Publikováno v:
Cancer Research. 76:1283-1283
Hepatocellular carcinoma (HCC) is an endemic disease globally, with a 5-year survival rate of 15%. Current treatment of late-stage HCC involves the use of chemotherapy and sorafenib, a multi-kinase inhibitor. Metabolic studies have indicated HCC has