Zobrazeno 1 - 10
of 1 575
pro vyhledávání: '"Gilthorpe"'
Autor:
Sandhya Malla, Kanchan Kumari, Carlos A. García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T. T. Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andre Mateus, Dung-Fang Lee, Claudio Cantù, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early embryogenesis and development. Here we show that LSD1 is dispensable for mouse embryonic stem
Externí odkaz:
https://doaj.org/article/2d6f847ecfc84532b688deb0fc0250d8
Autor:
Tennant, Peter W. G., Tomova, Georgia D., Murray, Eleanor J., Arnold, Kellyn F., Fox, Matthew P., Gilthorpe, Mark S.
BACKGROUND: In 1967, Frederick Lord posed a conundrum that has confused scientists for over 50-years. Subsequently named Lord's 'paradox', the puzzle centres on the observation that two common approach to analyses of 'change' between two time-points
Externí odkaz:
http://arxiv.org/abs/2302.01822
Autor:
Berrie, Laurie, Arnold, Kellyn F., Tomova, Georgia D., Gilthorpe, Mark S., Tennant, Peter W. G.
Deterministic variables are variables that are fully explained by one or more parent variables. They commonly arise when a variable has been algebraically constructed from one or more parent variables, as with composite variables, and in compositiona
Externí odkaz:
http://arxiv.org/abs/2211.13201
Autor:
Longjun Pu, Jing Wang, Qiongxuan Lu, Lars Nilsson, Alison Philbrook, Anjali Pandey, Lina Zhao, Robin van Schendel, Alan Koh, Tanara V. Peres, Weheliye H. Hashi, Si Lhyam Myint, Chloe Williams, Jonathan D. Gilthorpe, Sun Nyunt Wai, Andre Brown, Marcel Tijsterman, Piali Sengupta, Johan Henriksson, Changchun Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract G protein-coupled receptors (GPCRs) mediate responses to various extracellular and intracellular cues. However, the large number of GPCR genes and their substantial functional redundancy make it challenging to systematically dissect GPCR fun
Externí odkaz:
https://doaj.org/article/24e1b9e01e0d43e0a19e2412288d53fd
Publikováno v:
Medicina, Vol 60, Iss 8, p 1343 (2024)
Background and Objective: An unexpected batch-dependent safety signal for the BNT162b2 mRNA COVID-19 vaccine was recently identified in a nationwide study from Denmark, but the generalizability of this finding is unknown. Therefore, we compared batch
Externí odkaz:
https://doaj.org/article/8271b09cbe1049a8b3f1cfca8b573833
Autor:
Anna Månberg, Nathan Skene, Folkert Sanders, Anna Szczepinska, Julia Remnestål, Joke De Vocht, Jasper Anink, Hermieneke Vergunst-Bosch, Elena Rodriguez-Vieitez, Jonathan Gilthorpe, Robert Harris, Eleonora Aronica, Philip Van Damme, Albert Ludolph, Jan Veldink, Caroline Ingre, Peter Nilsson KTH, Sebastian Lewandowski
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100049- (2024)
Externí odkaz:
https://doaj.org/article/7b68d73550ef4c519015b43801d16c82
Publikováno v:
BMC Medical Research Methodology, Vol 11, Iss 1, p 82 (2011)
Abstract Background We investigate whether the changing environment caused by rapid economic growth yielded differential effects for successive Taiwanese generations on 8 components of metabolic syndrome (MetS): body mass index (BMI), systolic blood
Externí odkaz:
https://doaj.org/article/ed0f7d768cc94e36a4ace54de1ce15f3
Publikováno v:
BMC Health Services Research, Vol 11, Iss 1, p 53 (2011)
Abstract Background Using routinely collected patient data we explore the utility of multilevel latent class (MLLC) models to adjust for patient casemix and rank Trust performance. We contrast this with ranks derived from Trust standardised mortality
Externí odkaz:
https://doaj.org/article/0aeb52471f6843e5a4729432e0007a65
Publikováno v:
Neural Development, Vol 4, Iss 1, p 27 (2009)
Abstract Background Capricious is a Drosophila adhesion molecule that regulates specific targeting of a subset of motor neurons to their muscle target. We set out to identify whether one of its vertebrate homologues, Lrrn2, might play an analogous ro
Externí odkaz:
https://doaj.org/article/dad5fc3ee13e4b48bbcf6312d919625f
Autor:
Tsioras, Konstantinos, Smith, Kevin C., Edassery, Seby L., Garjani, Mehraveh, Li, Yichen, Williams, Chloe, McKenna, Elizabeth D., Guo, Wenxuan, Wilen, Anika P., Hark, Timothy J., Marklund, Stefan L., Ostrow, Lyle W., Gilthorpe, Jonathan D., Ichida, Justin K., Kalb, Robert G., Savas, Jeffrey N., Kiskinis, Evangelos
Publikováno v:
In Cell Reports 31 October 2023 42(10)