Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gilson J. Sanchez"'
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/85b114e73f3b4744bce6921530f3eab5
Publikováno v:
Transcription
Nascent transcription assays, such as global run-on sequencing (GRO-seq) and precision run-on sequencing (PRO-seq), have uncovered a myriad of unstable RNAs being actively produced from numerous sites genome-wide. These transcripts provide a more com
Autor:
Jennifer M. Skidmore, Hui Yao, Ricardo D’Oliveira Albanus, Gilson J. Sanchez, Alina Saiakhova, Stephanie L. Bielas, Stephen C. J. Parker, Mats Ljungman, Peter C. Scacheri, Donna M. Martin, Douglas F Hannum, Wenjia Lou, Yiwen Zhai, Sophie F. Hill
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
CHARGE syndrome, a rare multiple congenital anomaly condition, is caused by haploinsufficiency of the chromatin remodeling protein gene CHD7 (Chromodomain helicase DNA binding protein 7). Brain abnormalities and intellectual disability are commonly o
Autor:
Joseph Azofeifa, Phillip A. Richmond, Qinghong Zhang, Xuedong Liu, Cathryn M Toomey, Graycen Wheeler, Robin D. Dowell, Eric Bunker, Samuel S Karman, Aaron T. Garnett, Gilson J Sanchez, Quanbin Xu
Publikováno v:
Nucleic Acids Research
Histone deacetylase inhibitors (HDACIs) are known to alter gene expression by both up- and down-regulation of protein-coding genes in normal and cancer cells. However, the exact regulatory mechanisms of action remain uncharacterized. Here we investig
Publikováno v:
The FASEB Journal. 32
Autor:
Hui Yao, Donald L. Swiderski, Yehoash Raphael, Gilson J. Sanchez, Shigeki Iwase, Sophie F. Hill, Ethan D. Sperry, Cynthia F. Bartels, Peter C. Scacheri, Donna M. Martin, Jennifer M. Skidmore
Publikováno v:
JCI Insight, Vol 3, Iss 4 (2018)
CHD7, an ATP-dependent chromatin remodeler, is disrupted in CHARGE syndrome, an autosomal dominant disorder characterized by variably penetrant abnormalities in craniofacial, cardiac, and nervous system tissues. The inner ear is uniquely sensitive to
Autor:
Deepayan Sarkar, Jerry Davison, Martin Morgan, Maura H. Parker, Gilson J. Sanchez, Michael S. Lawrence, Stephen J. Tapscott, Kyle L. MacQuarrie, Walter L. Ruzzo, Zizhen Yao, Yi Cao, Robert Gentleman
Publikováno v:
Developmental Cell. 18(4):662-674
SummaryRecent studies have demonstrated that MyoD initiates a feed-forward regulation of skeletal muscle gene expression, predicting that MyoD binds directly to many genes expressed during differentiation. We have used chromatin immunoprecipitation a