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Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

Autor: Qiao, Xiaohang, van der Zanden, Sabina Y., Wander, Dennis P. A., Borràs, Daniel M., Song, Ji-Ying, Li, Xiaoyang, van Duikeren, Suzanne, van Gils, Noortje, Rutten, Arjo, van Herwaarden, Tessa, van Tellingen, Olaf, Giacomelli, Elisa, Bellin, Milena, Orlova, Valeria, Tertoolen, Leon G. J., Gerhardt, Sophie, Akkermans, Jimmy J., Bakker, Jeroen M., Zuur, Charlotte L., Pang, Baoxu, Smits, Anke M., Mummery, Christine L., Smith, Linda, Arens, Ramon, Li, Junmin, Overkleeft, Hermen S., Neefjes, Jacques

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun . 117(26), 15182-15192.

Externí odkaz: https://www.jstor.org/stable/26935068

IGFBP7 Induces Differentiation and Loss of Survival of Human Acute Myeloid Leukemia Stem Cells without Affecting Normal Hematopoiesis

Autor: Verhagen, Han J.M.P., van Gils, Noortje, Martiañez, Tania, van Rhenen, Anna, Rutten, Arjo, Denkers, Fedor, de Leeuw, David C., Smit, Marjon A., Tsui, Mei-Ling, de Vos Klootwijk, Louise L.E., Menezes, Renee X., Çil, Meyram, Roemer, Margaretha G.M., Vermue, Eline, Heukelom, Stan, Zweegman, Sonja, Janssen, Jeroen J.W.M., Ossenkoppele, Gert J., Schuurhuis, Gerrit Jan, Smit, Linda

Publikováno v: In Cell Reports 11 December 2018 25(11):3021-3035

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Therapeutic target identification and drug-target validation for acute myeloid leukemia

Autor: van Gils, Noortje

Publikováno v: van Gils, N 2022, ' Therapeutic target identification and drug-target validation for acute myeloid leukemia ', Doctor of Philosophy, Vrije Universiteit Amsterdam, Leiden . < https://hdl.handle.net/1871.1/42db4527-8009-406a-9069-bf0871c991c8 >
van Gils, N 2022, ' Therapeutic target identification and drug-target validation for acute myeloid leukemia ', PhD, Vrije Universiteit Amsterdam, Leiden .

Acute myeloid leukemia (AML) is a hematological malignancy characterized by accumulation of immature myeloid cells with aberrant proliferation, differentiation and survival capacity in the patient’s bone marrow (BM) and peripheral blood. Most AML p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9a6b2f8c45d702c3e31c854b149019ff
https://research.vu.nl/en/publications/42db4527-8009-406a-9069-bf0871c991c8