Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gilnam Lee"'
Induction of immunoglobulin transcription factor 2 and resistance to MEK inhibitor in melanoma cells
Autor:
Juhyun Moon, Gilnam Lee, Suk Young Cho, Yunsuk Choi, Jene Choi, Choung-Soo Kim, Sang-Hwa Yang, Kyun-Seop Bae, Jeongbeob Seo, Je-Hwan Lee, Bon-Kwan Goo, Jung Jin Hwang, Eun-Hye Hur
Publikováno v:
Oncotarget
Primary or acquired resistance to MEK inhibitors has been a barrier to successful treatment with MEK inhibitors in many tumors. In this study, we analyzed genome-wide gene expression profiling data from 6 sensitive and 6 resistant cell lines to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e708adb934013711f3efe42dff0c69c6
http://europepmc.org/articles/PMC5522248
http://europepmc.org/articles/PMC5522248
Autor:
Suk Young Cho, Woori Jo, Young Hee Yoon, Gilnam Lee, Eun Kyung Choi, Jung Jin Hwang, Hyun-Ji Choi, Bongcheol Kim, Woo-Chan Son, Joo Yong Lee, Hyun-Kyu Park, Jeongbeob Seo, Choung-Soo Kim
Publikováno v:
Journal of Applied Toxicology. 35:199-204
Many systemic drugs can induce ocular toxicity and several ocular side-effects have been identified in clinical studies. However, it is difficult to detect ocular toxicity in preclinical studies because of the lack of appropriate evaluation methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480e0151c955ff07926dcd78d516de0d
https://doi.org/10.1002/jat.3009
https://doi.org/10.1002/jat.3009
Autor:
Hyun-Kyu, Park, Woori, Jo, Hyun-Ji, Choi, Bongcheol, Kim, Gilnam, Lee, Jeongbeob, Seo, Suk Young, Cho, Choung-Soo, Kim, Eun Kyung, Choi, Jung Jin, Hwang, Joo Yong, Lee, Young Hee, Yoon, Woo-Chan, Son
Publikováno v:
Journal of applied toxicology : JAT. 35(2)
Many systemic drugs can induce ocular toxicity and several ocular side-effects have been identified in clinical studies. However, it is difficult to detect ocular toxicity in preclinical studies because of the lack of appropriate evaluation methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b03b956c35b1dc5759f981d0ebbfcdf3
https://pubmed.ncbi.nlm.nih.gov/24677158
https://pubmed.ncbi.nlm.nih.gov/24677158
Autor:
Suk Young Cho, Je-Hwan Lee, Gilnam Lee, Jung Jin Hwang, Choung-Soo Kim, Se Jin Jang, Jeongbeob Seo, Sang-wook Lee, Chulsoo Lim, Jene Choi, Ji-young Song
Publikováno v:
Investigational new drugs. 31(6)
Epidermal growth factor receptor (EGFR) gene mutations activate the KRAS-RAF-MEK-ERK pathway in lung cancer cells. EGFR tyrosine kinase inhibitors (TKIs) such as gefitinib induce apoptosis of cancer cells, but prolonged treatment is often associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f14818c6d0a2674af6b6cdbb136da05
https://pubmed.ncbi.nlm.nih.gov/24068620
https://pubmed.ncbi.nlm.nih.gov/24068620