Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection.

Autor: Alcorn MDH; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261., Sun C; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261., Gilliland TC Jr; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261., Lukash T; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261., Crasto CM; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA., Raju S; Department of Medicine and Pathology & Immunology, Washington University in St. Louis, St. Louis, MO 63110., Diamond MS; Department of Medicine and Pathology & Immunology, Washington University in St. Louis, St. Louis, MO 63110.; Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110., Weaver SC; Institute for Human Infections and Immunity and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555., Klimstra WB; Department of Immunology and Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA 15261.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 04. Date of Electronic Publication: 2024 Nov 04.

Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope.

Autor: Kim AS; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Kafai NM; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Winkler ES; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Gilliland TC Jr; Center for Vaccine Research and Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Cottle EL; Center for Vaccine Research and Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Earnest JT; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Jethva PN; Department of Chemistry, Washington University in St. Louis, Saint Louis, MO 63130, USA., Kaplonek P; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA., Shah AP; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Fong RH; Integral Molecular, Inc., Philadelphia, PA 19104, USA., Davidson E; Integral Molecular, Inc., Philadelphia, PA 19104, USA., Malonis RJ; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Quiroz JA; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Williamson LE; Vanderbilt Vaccine Center and Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Vang L; Emergent BioSolutions, Gaithersburg, MD 20879, USA., Mack M; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany., Crowe JE Jr; Vanderbilt Vaccine Center and Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Doranz BJ; Integral Molecular, Inc., Philadelphia, PA 19104, USA., Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA., Gross ML; Department of Chemistry, Washington University in St. Louis, Saint Louis, MO 63130, USA., Klimstra WB; Center for Vaccine Research and Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Fremont DH; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA; Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: diamond@wusm.wustl.edu.

Publikováno v: Cell [Cell] 2021 Aug 19; Vol. 184 (17), pp. 4414-4429.e19.

Immunogenicity and protective efficacy of recombinant Campylobacter jejuni flagellum-secreted proteins in mice.

Autor: Baqar S; Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910-7500, USA. shahida.baqar@med.navy.mil, Applebee LA, Gilliland TC Jr, Lee LH, Porter CK, Guerry P

Publikováno v: Infection and immunity [Infect Immun] 2008 Jul; Vol. 76 (7), pp. 3170-5. Date of Electronic Publication: 2008 Apr 21.