BUB-1 promotes amphitelic chromosome biorientation via multiple activities at the kinetochore

Autor: Frances Edwards, Gilliane Maton, Nelly Gareil, Julie C Canman, Julien Dumont

Publikováno v: eLife, Vol 7 (2018)

Accurate chromosome segregation relies on bioriented amphitelic attachments of chromosomes to microtubules of the mitotic spindle, in which sister chromatids are connected to opposite spindle poles. BUB-1 is a protein of the Spindle Assembly Checkpoi

Externí odkaz: https://doaj.org/article/f554c047da1f4544ae5454f701ef3d16

Author response: Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly

Autor: Frances Edwards, Kimberley Laband, Laura Bellutti, Nicolas Macaisne, Laras Pitayu-Nugroho, Alison Gervais, Thadshagine Ganeswaran, Hélène Geoffroy, Gilliane Maton, Julie C Canman, Benjamin Lacroix, Julien Dumont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdf4de915d1460a7b231a7ab5a19c123
https://doi.org/10.7554/elife.82579.sa2

Physiological involvement of presynaptic L-type voltage-dependent calcium channels in GABA release of cerebellar molecular layer interneurons

Autor: Dalton James Surmeier, Soosung Kang, Richard B. Silverman, Thibault Collin, Stéphanie Rey, Shin’Ichiro Satake, Gilliane Maton, Isabel Llano

Publikováno v: Journal of neurochemistryREFERENCES. 155(4)

Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152acde5029b576da1b83aeebb02dadc
https://pubmed.ncbi.nlm.nih.gov/32491217

Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing

Autor: Nicolas Minc, Gaëlle Letort, Laras Pitayu, Julie C. Canman, Benjamin Lacroix, Anne Marie Ladouceur, Marine Stefanutti, Paul S. Maddox, Amy Shaub Maddox, François Nédélec, Julien Dumont, Gilliane Maton, Jérémy Sallé

Publikováno v: Developmental Cell
Developmental Cell, Elsevier, 2018, 45 (4), pp.496-511.e6. ⟨10.1016/j.devcel.2018.04.022⟩
Developmental Cell, 2018, 45 (4), pp.496-511.e6. ⟨10.1016/j.devcel.2018.04.022⟩

International audience; Successive cell divisions during embryonic cleavage create increasingly smaller cells, so intracellular structures must adapt accordingly. Mitotic spindle size correlates with cell size, but the mechanisms for this scaling rem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79c32facb0aef9463e66f526f4d83fc
https://www.repository.cam.ac.uk/handle/1810/316718

Versatile kinetochore components control central spindle assembly

Autor: Gilliane Maton, Frances Edwards, Julien Dumont

Defects in cell division can lead to genomic instability and aneuploidy, both hallmarks of many cancers. During mitosis, sister chromatids are segregated on a microtubule-based spindle. Concomitant to spindle assembly, proteinaceous structures termed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f3499a5e19ae0750c144c35143b055
https://europepmc.org/articles/PMC4614393/