Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gillian T. Herbert"'
Autor:
Alexis R. Gibson, Mattie C. Pawlowic, Mastanbabu Somepalli, Gillian T. Herbert, Lizbeth Hedstrom, Gregory D. Cuny, Boris Striepen, Adam Sateriale
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Nucleotides are the activated building blocks for DNA and RNA as well as the major form of energy in all living organisms. Cells need to synthesize nucleotides to grow. Interference with this synthesis is thus widely used to treat infect
Autor:
Carrie F. Brooks, Julie B. Engiles, Boris Striepen, Christopher A. Hunter, Jan Šlapeta, Gillian T. Herbert, Emily M. Kugler, Jodi A. Gullicksrud, Jessica C. Kissinger, Adam Sateriale, Rodrigo P. Baptista
Publikováno v:
SSRN Electronic Journal.
Cryptosporidium is a leading cause of diarrheal disease and an important contributor to early childhood mortality, malnutrition, and growth faltering. Older children in high endemicity regions appear resistant to infection, while previously unexposed
Autor:
Alejandro Castellanos-Gonzalez, Wesley C. Van Voorhis, Lynn K. Barrett, Samuel L.M. Arnold, Sumiti Vinayak, Dana P. Betzer, Michael W. Riggs, Dustin J. Maly, Kasey Rivas, Boris Striepen, Gillian T. Herbert, Kayode K. Ojo, Carrie F. Brooks, Rama Subba Rao Vidadala, Ryan Choi, A. Clinton White, Grant R. Whitman, Deborah A. Schaefer, Hayley Sparks, Matthew A. Hulverson
Publikováno v:
The Journal of infectious diseases. 215(8)
Bumped kinase inhibitors (BKIs) of Cryptosporidium parvum calcium-dependent protein kinase 1 (CpCDPK1) are leading candidates for treatment of cryptosporidiosis-associated diarrhea. Potential cardiotoxicity related to anti-human ether-a-go-go potassi
Autor:
Gillian T. Herbert, Emily M. Kugler, Rodrigo P. Baptista, Adam Sateriale, Christopher A. Hunter, Jodi A. Gullicksrud, Boris Striepen, Carrie F. Brooks, Jessica C. Kissinger, Jan Šlapeta, Julie B. Engiles
Publikováno v:
Cell Host & Microbe. 26:135-146.e5
Summary Cryptosporidium is a leading cause of diarrheal disease and an important contributor to early childhood mortality, malnutrition, and growth faltering. Older children in high endemicity regions appear resistant to infection, while previously u
Autor:
Thierry T. Diagana, Suresh B. Lakshminarayana, Susan Noh, Francesca Blasco, Carrie F. Brooks, Jennifer A. Zambriski, Laura B. Goodman, Gu Feng, Sumiti Vinayak, Gillian T. Herbert, Peter Gedeck, Lijun Zhang, Jayesh Tandel, Siau H. Lim, Christian G. Noble, F. Joel Leong, Alex Chao, Juergen Wagner, Bin Zou, Boris Striepen, Tracy Sy, Ravinder Reddy Kondreddi, Christophe Bodenreider, Ujjini H. Manjunatha, Ghislain M. C. Bonamy, Adam Sateriale
Publikováno v:
Nature
Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a leading cause of paediatric diarrhoea, with particularly grave impact on infants and immunocompr