Výsledky vyhledávání - "Gillian Sadler"

Characterization of specific binding by mass spectrometry: Associations of E. coli citrate synthase with NADH and 2-azidoATP

Autor: Vincent C. Chen, Gillian Sadler, Harry W. Duckworth, Hélène Perreault, Mark E. McComb

Publikováno v: International Journal of Mass Spectrometry. 305:238-246

Type II citrate synthases (CSs), found in gram-negative bacteria such as Escherichia coli , are subject to strong and specific allosteric inhibition by NADH. Crystallographic studies have shown that the NADH binding sites are located at macromolecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9072dab1d460dede8946fcc9eb853dd6
https://doi.org/10.1016/j.ijms.2010.11.014

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Probing the Roles of Key Residues in the Unique Regulatory NADH Binding Site of Type II Citrate Synthase of Escherichia coli

Autor: David J. Stokell, Philip G. Hultin, Nham T. Nguyen, Robert Maurus, Harry W. Duckworth, Gary D. Brayer, Gillian Sadler, Lynda J. Donald, Kajal Choudhary

Publikováno v: Journal of Biological Chemistry. 278:35435-35443

The citrate synthase of Escherichia coli is an example of a Type II citrate synthase, a hexamer that is subject to allosteric inhibition by NADH. In previous crystallographic work, we defined the NADH binding sites, identifying nine amino acids whose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be16185607743bbf4954e2cf2181dd79
https://doi.org/10.1074/jbc.m302786200

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