Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gillian R. Douce"'
Autor:
Paola Lanzoni-Mangutchi, Oishik Banerji, Jason Wilson, Anna Barwinska-Sendra, Joseph A. Kirk, Filipa Vaz, Shauna O’Beirne, Arnaud Baslé, Kamel El Omari, Armin Wagner, Neil F. Fairweather, Gillian R. Douce, Per A. Bullough, Robert P. Fagan, Paula S. Salgado
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The S-layer is a two-dimensional protein array that covers the cell surface of many bacteria and archaea. Here, the authors use high-resolution X-ray crystallography and electron microscopy to provide detailed insights into S-layer organisation and a
Externí odkaz:
https://doaj.org/article/060e552494ad40e5a8e3a8037d7d898a
Autor:
James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation o
Externí odkaz:
https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
Autor:
Annie Aubry, Wei Zou, Evguenii Vinogradov, Dean Williams, Wangxue Chen, Greg Harris, Hongyan Zhou, Melissa J. Schur, Michel Gilbert, Gillian R. Douce, Susan M. Logan
Publikováno v:
Vaccines, Vol 8, Iss 1, p 73 (2020)
Abstract: The BclA3 glycoprotein is a major component of the exosporangial layer of Clostridium difficile spores and in this study we demonstrate that this glycoprotein is a major spore surface associated antigen. Here, we confirm the role of SgtA gl
Externí odkaz:
https://doaj.org/article/1c1b0413725e462bbe605af367d105fa
Autor:
James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author David Ruano-Gallego, which was incorrectly given as David R. Gallego. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3c7d3a9004e84e9fa8e7699baf6f939b
Autor:
Michael J Ormsby, Filipa Vaz, Joseph A Kirk, Anna Barwinska-Sendra, Jennifer C Hallam, Paola Lanzoni-Mangutchi, John Cole, Roy R Chaudhuri, Paula S Salgado, Robert P Fagan, Gillian R Douce
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011015 (2023)
Clostridioides difficile is responsible for substantial morbidity and mortality in antibiotically-treated, hospitalised, elderly patients, in which toxin production correlates with diarrhoeal disease. While the function of these toxins has been studi
Externí odkaz:
https://doaj.org/article/29ae89a68e0640afb2755f72cda25492
Autor:
Nicky O’Boyle, Gillian R. Douce, Gillian Farrell, Nicholas J. W. Rattray, Mark A. Schembri, Andrew J. Roe, James P. R. Connolly
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The ability of bacterial pathogens to adapt to host niches is driven by the carriage and regulation of genes that benefit pathogenic lifestyles. Genes that encode virulence or fitness-enhancing factors must be regulated in response to changing host e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69bda65e3cbeb476eb4e8d75c913ec59
https://doi.org/10.1073/pnas.2212175120
https://doi.org/10.1073/pnas.2212175120
Autor:
Michael J. Ormsby, Filipa Vaz, Joseph A. Kirk, Anna Barwinska-Sendra, Jennifer C. Hallam, Paola Lanzoni-Mangutchi, John Cole, Roy R. Chaudhuri, Paula S. Salgado, Robert P. Fagan, Gillian R Douce
Clostridioides difficileis responsible for substantial morbidity and mortality in antibiotically-treated, hospitalised, elderly patients, in which toxin production correlates with diarrhoeal disease. While the function of these toxins has been studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b1d4dd2aa6da04add1e8f03717be880
https://doi.org/10.1101/2022.11.22.517470
https://doi.org/10.1101/2022.11.22.517470
Autor:
Paola, Lanzoni-Mangutchi, Oishik, Banerji, Jason, Wilson, Anna, Barwinska-Sendra, Joseph A, Kirk, Filipa, Vaz, Shauna, O'Beirne, Arnaud, Baslé, Kamel, El Omari, Armin, Wagner, Neil F, Fairweather, Gillian R, Douce, Per A, Bullough, Robert P, Fagan, Paula S, Salgado
Publikováno v:
Nature communications. 13(1)
Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers the cell surface and plays crucial roles in cell physiology. Here, we report the crystal structure of SlpA, the main S-layer protein of the bacterial pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db4c5f14d356b221a51d35d006e58f9e
https://pubmed.ncbi.nlm.nih.gov/35217634
https://pubmed.ncbi.nlm.nih.gov/35217634
Autor:
Joseph A, Kirk, Dana, Gebhart, Anthony M, Buckley, Stephen, Lok, Dean, Scholl, Gillian R, Douce, Gregory R, Govoni, Robert P, Fagan
Publikováno v:
Science translational medicine. 9(406)
Avidocin-CDs are a new class of precision bactericidal agents that do not damage resident gut microbiota and are unlikely to promote the spread of antibiotic resistance. The precision killing properties result from the fusion of bacteriophage recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::904f51b8ee0854eb5b666d943119f492
https://pubmed.ncbi.nlm.nih.gov/28878013
https://pubmed.ncbi.nlm.nih.gov/28878013
Autor:
Alexandra, Faulds-Pain, Susan M, Twine, Evgeny, Vinogradov, Philippa C R, Strong, Anne, Dell, Anthony M, Buckley, Gillian R, Douce, Esmeralda, Valiente, Susan M, Logan, Brendan W, Wren
Publikováno v:
Molecular Microbiology
Clostridium difficile is a prominent nosocomial pathogen, proliferating and causing enteric disease in individuals with a compromised gut microflora. We characterized the post-translational modification of flagellin in C. difficile 630. The structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e89da2b9e25f6911b5cd89ba4ca299fe
https://pubmed.ncbi.nlm.nih.gov/25135277
https://pubmed.ncbi.nlm.nih.gov/25135277