Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gillian Payne"'
Autor:
Véronique Blanc, Lydie Mangatal-Wade, Julien Adam, Matteo Fassan, Raffaele Baffa, Marie Maguin, Stéphane Guérif, Chantal Carrez, Gillian Payne, Jan Pinkas, Marc Trombe, Alexia Tellier, Anne Caron, Céline Nicolazzi
IHC detection in normal human tissues of MUC1 glycoprotein and CA6 glycotope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a483bfce289322a76a8f4d1f989f7995
https://doi.org/10.1158/1535-7163.22520850
https://doi.org/10.1158/1535-7163.22520850
Autor:
Véronique Blanc, Lydie Mangatal-Wade, Julien Adam, Matteo Fassan, Raffaele Baffa, Marie Maguin, Stéphane Guérif, Chantal Carrez, Gillian Payne, Jan Pinkas, Marc Trombe, Alexia Tellier, Anne Caron, Céline Nicolazzi
Internalization of huDS6-Alexa 488 into tumor cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1206a3c78b3f35d6ae82d07124e11c9b
https://doi.org/10.1158/1535-7163.22520874.v1
https://doi.org/10.1158/1535-7163.22520874.v1
Autor:
Véronique Blanc, Lydie Mangatal-Wade, Julien Adam, Matteo Fassan, Raffaele Baffa, Marie Maguin, Stéphane Guérif, Chantal Carrez, Gillian Payne, Jan Pinkas, Marc Trombe, Alexia Tellier, Anne Caron, Céline Nicolazzi
Representative photomicrographs of different patterns of CA6 staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3294aea0d5bfe2bc0de0cb06a67b5a94
https://doi.org/10.1158/1535-7163.22520883
https://doi.org/10.1158/1535-7163.22520883
Autor:
Véronique Blanc, Lydie Mangatal-Wade, Julien Adam, Matteo Fassan, Raffaele Baffa, Marie Maguin, Stéphane Guérif, Chantal Carrez, Gillian Payne, Jan Pinkas, Marc Trombe, Alexia Tellier, Anne Caron, Céline Nicolazzi
Glycosylation is a complex multienzyme-related process that is frequently deregulated in cancer. Aberrant glycosylation can lead to the generation of novel tumor surface–specific glycotopes that can be targeted by antibodies. Murine DS6 mAb (muDS6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37241a54d688b6e25d64068a603daa08
https://doi.org/10.1158/1535-7163.c.6542814
https://doi.org/10.1158/1535-7163.c.6542814
Autor:
John M. Lambert, Thomas Chittenden, Victor S. Goldmacher, Jan Pinkas, Robert J. Lutz, Gillian Payne, Alyssa LaBelle, Daniel Tavares, Rajeeva Singh, Xiuxia Sun, Laura M. Bartle, Kathleen R. Whiteman, Olga Ab
Supplemental Figure S1. Activity of anti-FRα clones in an indirect cytotoxicity assay. Supplemental Figure S2. The antigen-dependent cell-mediated cytotoxic activity of M9346A antibody against Igrov-1 cells. Supplemental Figure S3. Activity of the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b36735412d2d96a25eefaa5052db13
https://doi.org/10.1158/1535-7163.22502020
https://doi.org/10.1158/1535-7163.22502020
Autor:
Virginia Liu-Compton, Yiwei Zhao, Gillian Payne, Ying Chen, Wesley Chen, Xinrong Liu, Alexandru C. Lazar
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 174:500-508
Host cell proteins (HCPs) are process-related impurities derived from the host organism such as Chinese hamster ovary (CHO) cells used for the production of therapeutic mAbs in biopharmaceuticals and potentially pose a risk to patient safety and prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050cd992aafb6386c856b4fe61b8ab5f
https://doi.org/10.1016/j.jpba.2019.06.021
https://doi.org/10.1016/j.jpba.2019.06.021
Autor:
Megan Bogalhas, Gillian Payne, Sven Loebrich, Erika Cohen, Yiwei Zhao, Mingfang Shen, Ying Chen
Publikováno v:
The AAPS Journal. 19:1223-1234
Antibody-drug-conjugates (ADCs) are an emerging class of biological therapeutics. Mirvetuximab soravtansine is a novel folate receptor alpha (FRα)-targeting ADC which represents a potential new treatment for patients with ovarian and other FRα-posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b588958d3dc3879a98f3a71fa1284394
https://doi.org/10.1208/s12248-017-0098-0
https://doi.org/10.1208/s12248-017-0098-0
Autor:
Gillian Payne, Lydie Mangatal-Wade, Alexia Tellier, Veronique Blanc, Julien Adam, Marc Trombe, Céline Nicolazzi, Raffaele Baffa, Anne Caron, Marie Maguin, Jan Pinkas, Stephane Guerif, Matteo Fassan, Chantal Carrez
Publikováno v:
Molecular cancer therapeutics. 19(8)
Glycosylation is a complex multienzyme-related process that is frequently deregulated in cancer. Aberrant glycosylation can lead to the generation of novel tumor surface–specific glycotopes that can be targeted by antibodies. Murine DS6 mAb (muDS6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf04e491099c0f3231ede2383e62e80
https://pubmed.ncbi.nlm.nih.gov/32451330
https://pubmed.ncbi.nlm.nih.gov/32451330
Publikováno v:
British Journal of Hospital Medicine. 76:196-199
Incidental left bundle–branch block occurs in up to 1.5% of healthy adults without symptoms or signs of cardiovascular disease. It may be found during investigation for non-cardiac disease, during preoperative assessment, private health screening o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f56ccd7846d965aacf5fe5761601fb
https://doi.org/10.12968/hmed.2015.76.4.196
https://doi.org/10.12968/hmed.2015.76.4.196
Autor:
Victor S. Goldmacher, Olga Ab, Gillian Payne, Laura M. Bartle, Thomas Chittenden, John M. Lambert, Kathleen R. Whiteman, Xiuxia Sun, Jan Pinkas, Robert J. Lutz, Daniel Tavares, Rajeeva Singh, Alyssa LaBelle
Publikováno v:
Molecular cancer therapeutics. 14(7)
A majority of ovarian and non–small cell lung adenocarcinoma cancers overexpress folate receptor α (FRα). Here, we report the development of an anti-FRα antibody–drug conjugate (ADC), consisting of a FRα-binding antibody attached to a highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10913254af5c0a4088dfab4ec1bf4544
https://pubmed.ncbi.nlm.nih.gov/25904506
https://pubmed.ncbi.nlm.nih.gov/25904506