Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gillian O'Hurley"'
Autor:
Gillian O'Hurley, Christer Busch, Linn Fagerberg, Björn M Hallström, Charlotte Stadler, Anna Tolf, Emma Lundberg, Jochen M Schwenk, Karin Jirström, Anders Bjartell, William M Gallagher, Mathias Uhlén, Fredrik Pontén
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133449 (2015)
To better understand prostate function and disease, it is important to define and explore the molecular constituents that signify the prostate gland. The aim of this study was to define the prostate specific transcriptome and proteome, in comparison
Externí odkaz:
https://doaj.org/article/59ff769d9ca449d28ad14f11428ec800
Autor:
William M. Gallagher, Darran P. O'Connor, Carlos Caldas, Karin Jirstrom, Sabine Linn, Thierry Dubois, John Crown, Elena Provenzano, Helen A. Bardwell, Suet-Feung Chin, Alexander Gaber, Emer Conroy, Finbarr Tarrant, Jesuchristopher Joseph, Girish Mallya Udupi, Gillian O'Hurley, Louise Walsh, Aisling E. O'Connor, Rut Klinger, Stephen F. Madden, Yue Fan, Triona Ni Chonghaile, Bo Li
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6953c09fe92bff1bb88ca3fce96c1c
https://doi.org/10.1158/0008-5472.22414061.v1
https://doi.org/10.1158/0008-5472.22414061.v1
Autor:
William M. Gallagher, Darran P. O'Connor, Carlos Caldas, Karin Jirstrom, Sabine Linn, Thierry Dubois, John Crown, Elena Provenzano, Helen A. Bardwell, Suet-Feung Chin, Alexander Gaber, Emer Conroy, Finbarr Tarrant, Jesuchristopher Joseph, Girish Mallya Udupi, Gillian O'Hurley, Louise Walsh, Aisling E. O'Connor, Rut Klinger, Stephen F. Madden, Yue Fan, Triona Ni Chonghaile, Bo Li
Antibody optimization for immunohistochemical assessment of CDK7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59284cb2fd87fd4233cbeecd30fc85dc
https://doi.org/10.1158/0008-5472.22414076
https://doi.org/10.1158/0008-5472.22414076
Autor:
William M. Gallagher, Darran P. O'Connor, Carlos Caldas, Karin Jirstrom, Sabine Linn, Thierry Dubois, John Crown, Elena Provenzano, Helen A. Bardwell, Suet-Feung Chin, Alexander Gaber, Emer Conroy, Finbarr Tarrant, Jesuchristopher Joseph, Girish Mallya Udupi, Gillian O'Hurley, Louise Walsh, Aisling E. O'Connor, Rut Klinger, Stephen F. Madden, Yue Fan, Triona Ni Chonghaile, Bo Li
Triple-negative breast cancer (TNBC) patients commonly exhibit poor prognosis and high relapse after treatment, but there remains a lack of biomarkers and effective targeted therapies for this disease. Here, we report evidence highlighting the cell-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0623ce1fb768e3d4d1ca507891dbb456
https://doi.org/10.1158/0008-5472.c.6508880
https://doi.org/10.1158/0008-5472.c.6508880
Autor:
Gillian O'Hurley, Maria Prencipe, William M. Gallagher, Aurelie Fabre, Elaine W. Kay, Lan K. Nguyen, Amanda O'Neill, R. William G. Watson, Colm Morrissey, Anders Bjartell
Publikováno v:
The Prostate. 75:1704-1717
BACKGROUND. Serum response factor (SRF) is an important transcription factor in castrate-resistant prostate cancer (CRPC). Since CRPC is associated with androgen receptor (AR) hypersensitivity, we investigated the relationship between SRF and AR. MAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64e839a60d2d83f7c1c219ca49f3790
https://doi.org/10.1002/pros.23051
https://doi.org/10.1002/pros.23051
Autor:
Louise Walsh, Bo Li, John Crown, Karin Jirström, Helen Bardwell, Alexander Gaber, Yue Fan, Thierry Dubois, Suet-Feung Chin, Carlos Caldas, Stephen F. Madden, Elena Provenzano, Aisling O'Connor, Sabine C. Linn, Gillian O'Hurley, Girish Mallya Udupi, Triona Ni Chonghaile, William M. Gallagher, Jesuchristopher Joseph, Darran P. O'Connor, Emer Conroy, Finbarr Tarrant, Rut Klinger
Publikováno v:
Cancer Research, 77(14), 3834. American Association for Cancer Research Inc.
Triple-negative breast cancer (TNBC) patients commonly exhibit poor prognosis and high relapse after treatment, but there remains a lack of biomarkers and effective targeted therapies for this disease. Here, we report evidence highlighting the cell-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a467fd772b6b0c675614209f3d89c0
https://dspace.library.uu.nl/handle/1874/355880
https://dspace.library.uu.nl/handle/1874/355880
Autor:
Fredrik Pontén, Caroline Kampf, Evelina Sjöstedt, Gillian O'Hurley, Cecilia Lindskog, Bo Li, Arman Rahman, William M. Gallagher
Publikováno v:
Molecular Oncology
The use of immunohistochemistry (IHC) in clinical cohorts is of paramount importance in determining the utility of a biomarker in clinical practice. A major bottleneck in translating a biomarker from bench‐to‐bedside is the lack of well character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f814e550a55c81261486f78648811c7e
http://europepmc.org/articles/PMC5528533
http://europepmc.org/articles/PMC5528533
Autor:
Anders Bjartell, Jochen M. Schwenk, Claudia Fredolini, Mathias Uhlén, Peter Nilsson, Gillian O'Hurley, Fredrik Wiklund, Henrik Johannesson, Ulrika Qundos, Rui M. M. Branca
Publikováno v:
Translational Proteomics, Vol 2, Iss C, Pp 14-24 (2014)
There is a need for a better differentiation of aggressive tumors in prostate cancer to design a tailored treatment for each patient, preferably by a minimally invasive analysis of blood samples. In a previous study, we discovered a decrease of plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d90d7914138ca52121fe92111e57348
Autor:
R. William G. Watson, Colm Morrissey, Maria Prencipe, Dara Lundon, Elaine W. Kay, Gillian O'Hurley, Susie Boyce, Amanda O'Neill, William M. Gallagher, Anthony O'Grady
Publikováno v:
The Prostate. 74:306-313
BACKGROUND Castration-resistant prostate cancer (CRPC) represents a challenge to treat with no effective treatment options available. We recently identified serum response factor (SRF) as a key transcription factor in an in vitro model of castration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1df0314e07a07da2c715c57f6297f36
https://doi.org/10.1002/pros.22752
https://doi.org/10.1002/pros.22752
Autor:
Robert Cummins, Cecily Quinn, Etáin Daly, Aisling Pierce, Michael J. Duffy, Elaine W. Kay, Yue Fan, Mairin Rafferty, Dara M. FitzGerald, Miriam A Lynn, Fredrik Pontén, Louise Flanagan, Anthony O'Grady, Gillian O'Hurley, Karin Jirström, William M. Gallagher
Publikováno v:
Histopathology. 64:660-670
Aims Triple-negative breast cancer (TNBC) is responsible for a disproportionate number of breast cancer (BC) deaths, owing to its intrinsic aggressiveness and a lack of treatment options, especially targeted therapies. Thus, there is an urgent need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e97c5ed864bbaf8b9d1afb27c17eb3
https://doi.org/10.1111/his.12313
https://doi.org/10.1111/his.12313