Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gillian McEachern"'
Publikováno v:
Human Molecular Genetics. 9:1041-1048
Human pyruvate dehydrogenase (PDH) complex deficiency is an extremely heterogeneous disease in its presentation and clinical course. We have characterized novel mutations that affect the C-terminal portion of the PDH-E(1)alpha-coding sequence. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed47d3c883c7b9d9500e0aa39a893fb
https://doi.org/10.1093/hmg/9.7.1041
https://doi.org/10.1093/hmg/9.7.1041
Publikováno v:
Free radical biologymedicine. 29(2)
In this report we show that ubiquinone cytochrome c reductase (complex III) from isolated rat heart mitochondria when inhibited with antimycin A, produces a large amount of superoxide as measured by the chemiluminescent probe coelenterazine. When mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf3ec3eb0900d3694b39e886d6cbefd
https://pubmed.ncbi.nlm.nih.gov/10980405
https://pubmed.ncbi.nlm.nih.gov/10980405
Autor:
Jacqueline M. Bourgeois, Sandeep Raha, Gillian McEachern, Brian H. Robinson, Sacha Kassovska-Bratinova, Mark A. Tarnopolsky, John Turnbull
Publikováno v:
Biochemical and biophysical research communications. 273(1)
The most frequent genetic causes of amyotrophic lateral sclerosis (ALS) determined so far are mutations occurring in the gene for copper/zinc superoxide dismutase (CuZnSOD). The mechanism may involve inappropriate formation of hyroxyl radicals, perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5608163d4c122a3a6ded07697dcd6b
https://pubmed.ncbi.nlm.nih.gov/10873611
https://pubmed.ncbi.nlm.nih.gov/10873611