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pro vyhledávání: '"Gillian M. Fraser"'
Autor:
Owain J. Bryant, Gillian M. Fraser
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Type III secretion systems (T3SSs) are essential for motility and virulence in many bacterial pathogens. Proteins destined for the flagellar T3SS contain at least two export signals in their N-terminal D0 domain. Here, we describe a third ca
Externí odkaz:
https://doaj.org/article/e5aa43f3233244aaa25c8e39ad151569
Autor:
Charlotte A. Green, Nitin S. Kamble, Elizabeth K. Court, Owain J. Bryant, Matthew G. Hicks, Christopher Lennon, Gillian M. Fraser, Phillip C. Wright, Graham P. Stafford
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background Many valuable biopharmaceutical and biotechnological proteins have been produced in Escherichia coli, however these proteins are almost exclusively localised in the cytoplasm or periplasm. This presents challenges for purification
Externí odkaz:
https://doaj.org/article/e452668ad75543f096a42f8f752f7056
Publikováno v:
Microbial Cell, Vol 1, Iss 2, Pp 64-66 (2014)
Flagella, the rotary propellers on the surface of bacteria, present a paradigm for how cells build and operate complex molecular ‘nanomachines’. Flagella grow at a constant rate to extend several times the length of the cell, and this is achieved
Externí odkaz:
https://doaj.org/article/669a52e586944d99862c3f300b4ea613
Publikováno v:
eLife, Vol 11 (2022)
Type III Secretion Systems (T3SS) deliver subunits from the bacterial cytosol to nascent cell surface flagella. Early flagellar subunits that form the rod and hook substructures are unchaperoned and contain their own export signals. A gate recognitio
Externí odkaz:
https://doaj.org/article/132d6625fc9049bcbb9c2fd91b86da01
Publikováno v:
Molecular Microbiology. 116:538-549
Bacterial flagellar subunits are exported across the cell membrane by the flagellar Type III Secretion System (fT3SS), powered by the proton motive force (pmf) and a specialized ATPase that enables the flagellar export gate to utilize the pmf electri
Autor:
Owain J. Bryant, Gillian M. Fraser
Publikováno v:
The FEBS journalReferences. 289(9)
Type III Secretion Systems (T3SS) transport proteins from the bacterial cytosol for assembly into cell surface nanomachines or direct delivery into target eukaryotic cells. At the core of the flagellar T3SS, the FlhAB-FliPQR export gate regulates pro
Autor:
Owain J. Bryant, Gillian M. Fraser
Type III Secretion Systems (T3SS) transport proteins from the bacterial cytosol for assembly into cell surface nanomachines or for direct delivery into target eukaryotic cells. At the core of the flagellar T3SS, the FlhAB-FliPQR export gate regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a3efe9e272957de95e0861e8eac1113
https://doi.org/10.1101/2021.01.17.426956
https://doi.org/10.1101/2021.01.17.426956