Výsledky vyhledávání - "Gillian M. Foley"

16p11.2 Deletion Syndrome Mice Display Sensory and Ultrasonic Vocalization Deficits During Social Interactions

Autor: Ricardo E. Dolmetsch, Christine V. Portfors, Thomas Portmann, Elena J. Mahrt, Freeman Lewis, Jacqueline N. Crawley, Gillian M. Foley, Mu Yang

Publikováno v: Autism Research. 8:507-521

Recurrent deletions and duplications at chromosomal region 16p11.2 are variably associated with speech delay, autism spectrum disorder, developmental delay, schizophrenia, and cognitive impairments. Social communication deficits are a primary diagnos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66e76e84c4665f35fab7b23fb381f27d
https://doi.org/10.1002/aur.1465

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16p11.2 Deletion mice display cognitive deficits in touchscreen learning and novelty recognition tasks

Autor: Gillian M. Foley, Freeman Lewis, Michael S. Sarvi, Mu Yang, Jacqueline N. Crawley

Publikováno v: Learning & memory (Cold Spring Harbor, N.Y.), vol 22, iss 12

Chromosomal 16p11.2 deletion syndrome frequently presents with intellectual disabilities, speech delays, and autism. Here we investigated the Dolmetsch line of 16p11.2 heterozygous (+/−) mice on a range of cognitive tasks with different neuroanatom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10755a41c4a9b038e88c0b1dadc297a
https://europepmc.org/articles/PMC4749736/

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Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan-McDermid Syndrome and autism

Autor: Nycole A. Copping, Jill L. Silverman, Beth L. Onaga, Nathalie Buscher, Gillian M. Foley, Melanie D. Schaffler, Elizabeth L. Berg, Mu Yang

Publikováno v: Neuroscience. 345

SHANK3 is a synaptic scaffolding protein localized in the postsynaptic density and has a crucial role in synaptogenesis and neural physiology. Deletions and point mutations in SHANK3 cause Phelan-McDermid Syndrome (PMS), and have also been implicated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945583050bfb8f8b5691826ba824316d
https://pubmed.ncbi.nlm.nih.gov/27189882

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In tribute to Bob Blanchard: Divergent behavioral phenotypes of 16p11.2 deletion mice reared in same-genotype versus mixed-genotype cages

Autor: Jacqueline N. Crawley, Freeman Lewis, Mu Yang, Gillian M. Foley

Publikováno v: Physiologybehavior. 146

Mouse models offer indispensable heuristic tools for studying genetic and environmental causes of neuropsychiatric disorders, including autism. Development of useful animal models of complex human behaviors depends not only on extensive knowledge of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d9c42e46de219e6e2a222485195a3f
https://pubmed.ncbi.nlm.nih.gov/26066718

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