Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Gillian Fitzgerald"'
Autor:
Gillian Fitzgerald, Guillermo Turiel, Tatiane Gorski, Inés Soro-Arnaiz, Jing Zhang, Nicola C. Casartelli, Evi Masschelein, Nicola A. Maffiuletti, Reto Sutter, Michael Leunig, Jean Farup, Katrien De Bock
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-21 (2023)
Using single nuclei and single cell RNA-seq, 3 FAP cell subpopulations are identified in human skeletal muscle, with an MME+ subset showing increased adipogenic potential under fatty infiltration conditions.
Externí odkaz:
https://doaj.org/article/6235bdf1b70e4784936defbd604d3383
Autor:
Gommaar D’Hulst, Inés Soro-Arnaiz, Evi Masschelein, Koen Veys, Gillian Fitzgerald, Benoit Smeuninx, Sunghoon Kim, Louise Deldicque, Bert Blaauw, Peter Carmeliet, Leigh Breen, Peppi Koivunen, Shi-Min Zhao, Katrien De Bock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
mTORC1 is an important regulator of muscle mass. Here, the authors show that the PHD1 controls muscle mass in a hydroxylation-independent manner. PHD1 prevents the degradation of leucine sensor LRS during oxygen and amino acid depletion to ensure eff
Externí odkaz:
https://doaj.org/article/57ce964136154da49cd0e8f1b72242c1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Endothelial cells (ECs) make up the lining of our blood vessels and they ensure optimal nutrient and oxygen delivery to the parenchymal tissue. In response to oxygen and/or nutrient deprivation, ECs become activated and sprout into hypo-vascularized
Externí odkaz:
https://doaj.org/article/1bd184e40465457b9f55f60e231fa586
Publikováno v:
Rheumatology International. 42:831-838
The Ankylosing Spondylitis Registry of Ireland (ASRI) captures both radiographic and non-radiographic axial spondyloarthritis (axSpA) in a large, well characterised cohort. This is a valuable resource for studies in therapeutics and burden of disease
Autor:
Gillian Fitzgerald, Guillermo Turiel, Tatiane Gorski, Inés Soro-Arnaiz, Jing Zhang, Nicola C Casartelli, Evi Masschelein, Nicola A Maffiuletti, Reto Sutter, Michael Leunig, Jean Farup, Katrien De Bock
Summary/AbstractFatty infiltration, the ectopic deposition of adipose tissue within skeletal muscle, is mediated via the adipogenic differentiation of fibro-adipogenic progenitors (FAPs). We used single-nuclei and single- cell RNA sequencing to chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39aa0cb4592af3d1468b6626fc4e620
https://doi.org/10.1101/2022.04.22.489158
https://doi.org/10.1101/2022.04.22.489158
Publikováno v:
Clinical Rheumatology. 39:1971-1979
The aim of this study was to investigate the role of quantitative ultrasound (QUS) of the calcaneus in screening for osteoporosis in adults with axial spondyloarthropathy (axSpA). Postmenopausal women and men over 50 years with axSpA were recruited f
Publikováno v:
International Journal of Rheumatic Diseases. 23:358-366
AIM Osteoporosis in axial spondyloarthropathy (axSpA) is difficult to accurately diagnose due to osteoproliferation of the spine interfering with conventional (anteroposterior, AP) dual-energy X-ray absorptiometry (DXA). This study compares AP and la
Autor:
Peter Carmeliet, Louise Deldicque, Sunghoon Kim, Shimin Zhao, Leigh Breen, Gillian Fitzgerald, Koen Veys, Peppi Koivunen, Benoit Smeuninx, Inés Soro-Arnaiz, Katrien De Bock, Bert Blaauw, Gommaar D'Hulst, Evi Masschelein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, vol 11, iss 1
Nature Communications, 11
Nature Communications
Nature Communications, Vol. 11, no. 1, p. 174 (2020)
Nature communications, vol 11, iss 1
Nature Communications, 11
Nature Communications
Nature Communications, Vol. 11, no. 1, p. 174 (2020)
mTORC1 is an important regulator of muscle mass but how it is modulated by oxygen and nutrients is not completely understood. We show that loss of the prolyl hydroxylase domain isoform 1 oxygen sensor in mice (PHD1KO) reduces muscle mass. PHD1KO musc
Autor:
Gillian Fitzgerald, Bart Ghesquière, Evi Masschelein, Christopher M. Adams, Abdiel Alvarado-Diaz, Tatiane Gorski, Paola Gilardoni, Tea Kocijan, Ge Tan, Raphaela Ardicoglu, Moheb Ghobrial, Katrien De Bock, Zheng Fan, Guillermo Turiel, Jing Zhang
Publikováno v:
Cell Metabolism
Cell Metabolism, 33 (9)
Cell Metabolism, 33 (9)
Summary Exercise is a powerful driver of physiological angiogenesis during adulthood, but the mechanisms of exercise-induced vascular expansion are poorly understood. We explored endothelial heterogeneity in skeletal muscle and identified two capilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ec368eb382b6593c359861a237c44f
https://lirias.kuleuven.be/handle/123456789/679037
https://lirias.kuleuven.be/handle/123456789/679037
Publikováno v:
The Journal of rheumatology. 48(12)
We read with interest the recent article from Mease et al1 regarding the analysis of men and women with axial spondyloarthritis (axSpA) captured in the Corrona Psoriatic Arthritis/ Spondyloarthritis Registry. Dedicated comparative analysis in large,