Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gillian Douce"'
Autor:
Caitlin A. Jukes, Umer Zeeshan Ijaz, Anthony Buckley, Janice Spencer, June Irvine, Denise Candlish, Jia V. Li, Julian R. Marchesi, Gillian Douce
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 481-496 (2020)
Susceptibility of patients to antibiotic-associated C. difficile disease is intimately associated with specific changes to gut microbiome composition. In particular, loss of microbes that modify bile salt acids (BSA) play a central role; primary bile
Externí odkaz:
https://doaj.org/article/835a8c4f15e743a9840b266c44c0c688
Autor:
Nuria Carpena, Kerry Richards, Teresita D. J. Bello Gonzalez, Alberto Bravo-Blas, Nicholas G. Housden, Konstantinos Gerasimidis, Simon W. F. Milling, Gillian Douce, Danish J. Malik, Daniel Walker
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models ar
Externí odkaz:
https://doaj.org/article/221a8f21675c4c71bcd4759b011ab381
Autor:
Carolina Albuquerque, Davide Pagnossin, Kirsten Landsgaard, Jessica Simpson, Derek Brown, June Irvine, Denise Candlish, Alison E Ridyard, Gillian Douce, Caroline Millins
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0245949 (2021)
Clostridioides difficile is a leading cause of human antibiotic-associated diarrhoeal disease globally. Zoonotic reservoirs of infection are increasingly suspected to play a role in the emergence of this disease in the community and dogs are consider
Externí odkaz:
https://doaj.org/article/a9a89dc43cef4c12a320dab01e953faf
Autor:
Alejandro Huerta-Uribe, Zoe Marjenberg, Nao Yamaguchi, Stephen Fitzgerald, James Patrick Connolly, Nuria Carpena, Hanna Uvell, Gillian Douce, Mikael Elofsson, Olwyn Byron, Rudi Marquez, David Gally, Andrew James Roe
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Infections caused by Shiga toxin-producing E. coli strains constitute a health problem, as they are problematic to treat. Shiga toxin (Stx) production is a key virulence factor associated with the pathogenicity of enterohaemorrhagic E. coli (EHEC) an
Externí odkaz:
https://doaj.org/article/59dfd3ccf9bc4531b18dc9eb88bf126a
Autor:
Raymond Kiu, Alexander G. Shaw, Kathleen Sim, Antia Acuna-Gonzalez, Christopher A. Price, Harley Bedwell, Sally A. Dreger, Wesley J. Fowler, Emma Cornwell, Derek Pickard, Gusztav Belteki, Jennifer Malsom, Sarah Phillips, Gregory R. Young, Zoe Schofield, Cristina Alcon-Giner, Janet E. Berrington, Christopher J. Stewart, Gordon Dougan, Paul Clarke, Gillian Douce, Stephen D. Robinson, J. Simon Kroll, Lindsay J. Hall
Clostridium perfringens is an anaerobic toxin-producing bacterium associated with intestinal diseases, particularly in neonatal humans and animals. Infant gut microbiome studies have recently indicated a link between C. perfringens and the preterm in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99cb2b07e2fd2a5bdf9eb9e6d97321b
https://www.repository.cam.ac.uk/handle/1810/350553
https://www.repository.cam.ac.uk/handle/1810/350553
Autor:
Jia V. Li, Janice Spencer, Julian R. Marchesi, Caitlin A Jukes, Anthony M. Buckley, June Irvine, Gillian Douce, Umer Zeeshan Ijaz, Denise Candlish
Publikováno v:
Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, Vol 11, Iss 3, Pp 481-496 (2020)
article-version (VoR) Version of Record
Gut Microbes, Vol 11, Iss 3, Pp 481-496 (2020)
Susceptibility of patients to antibiotic-associated C. difficile disease is intimately associated with specific changes to gut microbiome composition. In particular, loss of microbes that modify bile salt acids (BSA) play a central role; primary bile
Publikováno v:
Vaccine. 37:7300-7306
Clostridium difficile associated disease is fundamentally associated with dysbiosis of the gut microbiome as a consequence of antibiotic use. This is because this sporulating, obligate anaerobe germinates and proliferates rapidly in the dysbiotic gut
Autor:
Simon Milling, Danish J. Malik, Alberto Bravo-Blas, Daniel Walker, Kerry Richards, Konstantinos Gerasimidis, Nicholas G. Housden, Teresita D. J. Bello Gonzalez, Nuria Carpena, Gillian Douce
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, 12
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology 12 (2021)
Frontiers in Microbiology, 12
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology 12 (2021)
Bacteriocins are narrow-spectrum protein antibiotics that could potentially be used to engineer the human gut microbiota. However, technologies for targeted delivery of proteins to the lower gastrointestinal (GI) tract in preclinical animal models ar
Autor:
Victor H. Villar, Lynsey M. Meikle, Sheila Brown, Josephine Bunch, Emily K. Osterweil, Richard J. A. Goodwin, Maya Kamat, RuAngelie Edrada-Ebel, Justin J. J. van der Hooft, Michael J. Ormsby, Alex Dexter, Daniel Walker, Gillian Douce, Nicole Strittmatter, Julia M. Edgar, John G. Swales, Saverio Tardito, Jasper C. Komen, Ryan A. Bragg, Daniel M. Wall, Andrew S. MacDonald, Christopher J. Schofield, Heather Hulme, Stephanie A. Barnes, Richard Burchmore, Simon Milling
Publikováno v:
Hulme, H, Meikle, L M, Strittmatter, N, van der Hooft, J J J, Swales, J, Bragg, R A, Villar, V H, Ormsby, M J, Barnes, S, Brown, S L, Dexter, A, Kamat, M T, Komen, J C, Walker, D, Milling, S, Osterweil, E K, MacDonald, A S, Schofield, C J, Tardito, S, Bunch, J, Douce, G, Edgar, J M, Edrada-Ebel, R, Goodwin, R J A, Burchmore, R & Wall, D M 2020, ' Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication ', Science Advances, vol. 6, no. 11, eaax6328, pp. 1-10 . https://doi.org/10.1126/sciadv.aax6328
Science Advances 6 (2020) 11
Science Advances
Science Advances, 6(11)
Hulme, H, Meikle, L M, Strittmatter, N, van der Hooft, J J J, Swales, J, Bragg, R A, Villar, V H, Ormsby, M J, Barnes, S, Brown, S L, Dexter, A, Kamat, M T, Komen, J C, Walker, D, Milling, S, Osterweil, E K, MacDonald, A S, Schofield, C J, Tardito, S, Bunch, J, Douce, G, Edgar, J M, Edrada-Ebel, R, Goodwin, R J A, Burchmore, R & Wall, D M 2020, ' Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication ', Science Advances, vol. 6, no. 11, pp. eaax6328 . https://doi.org/10.1126/sciadv.aax6328
Science Advances 6 (2020) 11
Science Advances
Science Advances, 6(11)
Hulme, H, Meikle, L M, Strittmatter, N, van der Hooft, J J J, Swales, J, Bragg, R A, Villar, V H, Ormsby, M J, Barnes, S, Brown, S L, Dexter, A, Kamat, M T, Komen, J C, Walker, D, Milling, S, Osterweil, E K, MacDonald, A S, Schofield, C J, Tardito, S, Bunch, J, Douce, G, Edgar, J M, Edrada-Ebel, R, Goodwin, R J A, Burchmore, R & Wall, D M 2020, ' Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication ', Science Advances, vol. 6, no. 11, pp. eaax6328 . https://doi.org/10.1126/sciadv.aax6328
Discovery of novel bacterial metabolites reveals an unprecedented role for the microbiome in gut-brain axis communication.
Alterations to the gut microbiome are associated with various neurological diseases, yet evidence of causality and identit
Alterations to the gut microbiome are associated with various neurological diseases, yet evidence of causality and identit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6425116aa951a24b358ad25d9af7f085
https://doi.org/10.1126/sciadv.aax6328
https://doi.org/10.1126/sciadv.aax6328
Autor:
Kathleen Sim, Harley Bedwell, Gillian Douce, Sarah Philips, Lindsay J. Hall, Christopher J. Stewart, Gusztav Belteki, Gregory R Young, Zoe Schofield, Derek Pickard, J. Simon Kroll, Raymond Kiu, Cristina Alcon-Giner, Paul Clarke, Alexander G. Shaw, Janet E. Berrington, Jennifer Malsom, Gordon Dougan, Emma Cornwell
BackgroundClostridium perfringens is an anaerobic toxin-producing bacterium that has long been associated with intestinal diseases, particularly in neonatal humans and animals. More recently, infant gut microbiome studies have suggested an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2700b9e88faaf67d1445e4b2dc1348ef
https://doi.org/10.1101/2021.08.03.454877
https://doi.org/10.1101/2021.08.03.454877