Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gillian D. Pullinger"'
Autor:
Honorata M. Ropiak, Simon King, Marc Guimerà Busquets, Kerry Newbrook, Gillian D. Pullinger, Hannah Brown, John Flannery, Simon Gubbins, Carrie Batten, Paulina Rajko-Nenow, Karin E. Darpel
Publikováno v:
Viruses, Vol 13, Iss 9, p 1781 (2021)
Since the 2000s, the distribution of bluetongue virus (BTV) has changed, leading to numerous epidemics and economic losses in Europe. Previously, we found a BTV-4 field strain with a higher infection rate of a Culicoides vector than a BTV-1 field str
Externí odkaz:
https://doaj.org/article/8c9b8aea32954ed48055874165dfec1a
Autor:
Marc Guimerà Busquets, Gillian D. Pullinger, Karin E. Darpel, Lyndsay Cooke, Stuart Armstrong, Jennifer Simpson, Massimo Palmarini, Rennos Fragkoudis, Peter P. C. Mertens
Publikováno v:
Viruses, Vol 13, Iss 5, p 919 (2021)
Arboviruses such as bluetongue virus (BTV) replicate in arthropod vectors involved in their transmission between susceptible vertebrate-hosts. The “classical” BTV strains infect and replicate effectively in cells of their insect-vectors (Culicoid
Externí odkaz:
https://doaj.org/article/7b5d8abdf3584095923df9b42a366489
Autor:
Gillian D Pullinger, Marc Guimerà Busquets, Kyriaki Nomikou, Mark Boyce, Houssam Attoui, Peter P Mertens
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149709 (2016)
Bluetongue virus (BTV) can infect most ruminant species and is usually transmitted by adult, vector-competent biting midges (Culicoides spp.). Infection with BTV can cause severe clinical signs and can be fatal, particularly in naïve sheep and some
Externí odkaz:
https://doaj.org/article/ba4ba71d361c4500a862aeb754997b2d
Autor:
J.H. Williamson, S.J. Lacy-Hulbert, Raymond T. Cursons, Gillian D. Pullinger, Lopez-Benavides Mg, James A. Leigh
Publikováno v:
Journal of Dairy Science. 90:5558-5566
Microbiological and molecular tools were used to monitor Streptococcus uberis populations on farm tracks and paddocks on a dairy farm during different seasons of a year to identify and profile potential environmental niches of Strep. uberis in a past
Autor:
Alistair J. Lax, Gillian D. Pullinger
Publikováno v:
The Open Biochemistry Journal
We have investigated histidine residues near the active site of the mitogenic Pasteurella multocida toxin. Mutation of H1202 or H1228 had little effect, while the effect of mutation on H1223 depended on the amino acid substituted. Mutation of H1205 c
Autor:
Tracey J. Coffey, James A. Leigh, Gillian D. Pullinger, Stephen M. Wilson, Keith A. Jolley, Martin C. J. Maiden, Rachel Urwin
Publikováno v:
Applied and Environmental Microbiology. 72:1420-1428
Intramammary infection with Streptococcus uberis is a common cause of bovine mastitis throughout the world. Several procedures to differentiate S. uberis isolates have been proposed. However, all are prone to interlaboratory variation, and none is su
Autor:
Jane Lacy-Hulbert, Martin C. J. Maiden, Raymond T. Cursons, Tracey J. Coffey, James A. Leigh, Emma Louise Summers, John H. Williamson, Gillian D. Pullinger, Lopez-Benavides Mg
Publikováno v:
Applied and Environmental Microbiology. 72:1429-1436
We recently developed a multilocus sequence typing (MLST) scheme to differentiate S. uberis isolates and facilitate an understanding of the population biology of this pathogen. The scheme was initially used to study a collection of 160 bovine milk is
Autor:
Jeremy H. Lakey, Alistair J. Lax, D Harmey, Michael R. Baldwin, Agamemnon E. Grigoriadis, Gillian D. Pullinger
Publikováno v:
International Journal of Medical Microbiology. 293:505-512
Some years ago we showed that the Pasteurella multocida toxin (PMT) is a potent mitogen for cells in culture. It is an intracellularly acting toxin that stimulates several signal transduction pathways. The heterotrimeric G-protein, Gq, is stimulated,
Publikováno v:
Molecular Microbiology. 51:255-269
Toxigenic strains of Pasteurella multocida produce a 146 kDa toxin (PMT) that acts as a potent mitogen. Sequence analysis of the structural gene for PMT, toxA, previously suggested it was horizontally acquired, because it had a low G + C content rela
Publikováno v:
Acta Veterinaria Hungarica. 48:397-406
The effect of dermonecrotic toxin (DNT) expression of Bordetella bronchiseptica was studied in mice by comparing the pathology induced by a wild type strain with that induced by an isogenic DNT- strain in which part of the structural gene has been re