Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gillian C.A. Taylor"'
Publikováno v:
Wellcome Open Research, Vol 2 (2021)
Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional co
Externí odkaz:
https://doaj.org/article/820787b92f434a54a700e77f1112df08
Publikováno v:
Wellcome Open Research, Vol 2 (2021)
Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional co
Externí odkaz:
https://doaj.org/article/bdc675960f3e416cbb4e7fbe6ad19d7c
Autor:
Ioannis Christodoulou, Gillian C.A. Taylor, Andrew J. Wood, Jimi Wills, Dimitrios K. Papadopoulos, Lewis A Macdonald, Matilda Bui, Lucy Scott
Withdrawal Note:The authors have withdrawn their manuscript due to the discovery of artifacts that call into question key findings from the study. Both artifacts originate from cell-type differences that arose during sample processing, creating the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be57af74f123cbfb7f3c856fa0b4dff
https://doi.org/10.1101/2020.11.04.367847
https://doi.org/10.1101/2020.11.04.367847
Publikováno v:
Wellcome Open Research
Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fafd54fcf97410e8ab0faa32adc060
https://doi.org/10.12688/wellcomeopenres.11589.3
https://doi.org/10.12688/wellcomeopenres.11589.3
Autor:
Andrew J. Wood, Gillian C.A. Taylor, Erin E. Cutts, Jimi Wills, Alessandro Vannini, Jyoti S. Choudhary, Lu Yu, Mercedes Pardo
Publikováno v:
Wellcome Open Research
SummaryCondensin complexes compact and disentangle chromosomes in preparation for cell division. Commercially available antibodies raised against condensin subunits have been widely used to characterise their cellular interactome. Here we have assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fae8cab8ed246d8c35ef81b24da90ee
https://doi.org/10.12688/wellcomeopenres.16482.1
https://doi.org/10.12688/wellcomeopenres.16482.1
Autor:
Karen Blyth, Shelagh Boyle, Milica Vukovic, Juan Carlos Acosta, Mark J. Arends, Kirsteen J. Campbell, Andrew J. Wood, Dinesh C. Soares, Bauke Ylstra, Gillian C.A. Taylor, Keerthi T. Chathoth, Wendy A. Bickmore, Núria Tarrats, David Read, Andrew P. Jackson, Jessica Woodward, David Jamieson, Daoud Sie, Kamil R. Kranc
Publikováno v:
Genes and Development, 30(19), 2173-2186. Cold Spring Harbor Laboratory Press
Woodward, J, Taylor, G C, Soares, D C, Boyle, S, Sie, D, Read, D, Chathoth, K, Vukovic, M, Tarrats, N, Jamieson, D, Campbell, K J, Blyth, K, Acosta, J C, Ylstra, B, Arends, M J, Kranc, K R, Jackson, A P, Bickmore, W A & Wood, A J 2016, ' Condensin II mutation causes T cell lymphoma through tissue-specific genome instability ', Genes and Development, vol. 30, no. 19, pp. 2173-2186 . https://doi.org/10.1101/gad.284562.116
Woodward, J, Taylor, G C, Soares, D C, Boyle, S, Sie, D, Read, D, Chathoth, K, Vukovic, M, Tarrats, N, Jamieson, D, Campbell, K J, Blyth, K, Acosta, J C, Ylstra, B, Arends, M J, Kranc, K R, Jackson, A P, Bickmore, W A & Woods, A J 2016, ' Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability ', Genes and Development, vol. 30, no. 19, pp. 2173-2186 . https://doi.org/10.1101/gad.284562.116
Woodward, J, Taylor, G C, Soares, D C, Boyle, S, Sie, D, Read, D, Chathoth, K, Vukovic, M, Tarrats, N, Jamieson, D, Campbell, K J, Blyth, K, Acosta, J C, Ylstra, B, Arends, M J, Kranc, K R, Jackson, A P, Bickmore, W A & Wood, A J 2016, ' Condensin II mutation causes T cell lymphoma through tissue-specific genome instability ', Genes and Development, vol. 30, no. 19, pp. 2173-2186 . https://doi.org/10.1101/gad.284562.116
Woodward, J, Taylor, G C, Soares, D C, Boyle, S, Sie, D, Read, D, Chathoth, K, Vukovic, M, Tarrats, N, Jamieson, D, Campbell, K J, Blyth, K, Acosta, J C, Ylstra, B, Arends, M J, Kranc, K R, Jackson, A P, Bickmore, W A & Woods, A J 2016, ' Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability ', Genes and Development, vol. 30, no. 19, pp. 2173-2186 . https://doi.org/10.1101/gad.284562.116
Chromosomal instability is a hallmark of cancer, but mitotic regulators are rarely mutated in tumors. Mutations in the condensin complexes, which restructure chromosomes to facilitate segregation during mitosis, are significantly enriched in cancer g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1309b56f27b0467ccfd9f6ef79ff6b0a
https://doi.org/10.1101/gad.284562.116
https://doi.org/10.1101/gad.284562.116
Autor:
Gillian C.A. Taylor, Gabrielle Olley, Graeme R. Grimes, Yatendra Kumar, Madapura M. Pradeepa, Wendy A. Bickmore, Robert Schneider
Publikováno v:
Nature genetics
Pradeepa, M M, Grimes, G R, Kumar, Y, Olley, G, Taylor, G C A, Schneider, R & Bickmore, W A 2016, ' Histone H3 globular domain acetylation identifies a new class of enhancers ', Nature Genetics, vol. 48, no. 6, pp. 681–686 . https://doi.org/10.1038/ng.3550
Pradeepa, M M, Grimes, G R, Kumar, Y, Olley, G, Taylor, G C A, Schneider, R & Bickmore, W A 2016, ' Histone H3 globular domain acetylation identifies a new class of enhancers ', Nature Genetics, vol. 48, no. 6, pp. 681–686 . https://doi.org/10.1038/ng.3550
Histone acetylation is generally associated with active chromatin, but most studies have focused on the acetylation of histone tails. Various histone H3 and H4 tail acetylations mark the promoters of active genes. These modifications include acetylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3350a1de2d42f679050add21d21e2c
http://europepmc.org/articles/PMC4886833
http://europepmc.org/articles/PMC4886833
Autor:
Alison M. Meynert, Andrew J. Wood, Martijn J. E. Kelder, Robert Feil, Tracy Ballinger, Keerthi T. Chathoth, Ildem Sanli, Eirini M. Kallimasioti-Pazi, Sébastien Lalevée, Gillian C.A. Taylor
CRISPR-Cas9 genome editing occurs in the context of chromatin, which is heterogeneous in structure and function across the genome. Chromatin heterogeneity is thought to affect genome editing efficiency, but this has been challenging to quantify due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ca727ec93106708b2122e5b68936ca
Publikováno v:
Wellcome Open Research. 2:83
Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64b3c0c1276e95e2d19ac129dab3dc72
https://doi.org/10.12688/wellcomeopenres.11589.2
https://doi.org/10.12688/wellcomeopenres.11589.2
Publikováno v:
Wellcome Open Research. 2:83
Background: Trimethylation at histone H3 at lysine 36 (H3K36me3) is associated with expressed gene bodies and recruit proteins implicated in transcription, splicing and DNA repair. PC4 and SF2 interacting protein (PSIP1/LEDGF) is a transcriptional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05eedfcbf11147bc43848f2952012833
https://doi.org/10.12688/wellcomeopenres.11589.1
https://doi.org/10.12688/wellcomeopenres.11589.1