Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Gillian C. Lynch"'
Autor:
Abimbola O. Kolawole, Hong Q. Smith, Sophia A. Svoboda, Madeline S. Lewis, Michael B. Sherman, Gillian C. Lynch, B. Montgomery Pettitt, Thomas J. Smith, Christiane E. Wobus
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Ideal antiviral vaccines elicit antibodies (Abs) with broad strain recognition that bind to regions that are difficult to mutate for escape. Using 10 murine norovirus (MNV) strains and 5 human norovirus (HuNoV) virus-like particles (VLPs), w
Externí odkaz:
https://doaj.org/article/8c3e915739ee40cdb50d1aac4ea2b75c
Publikováno v:
Biophysical Journal. 121:527a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1850:923-931
Background Solvation density locations are important for protein dynamics and structure. Knowledge of the preferred hydration sites at biomolecular interfaces and those in the interior of cavities can enhance understanding of structure and function.
Autor:
B. Montgomery Pettitt, Melinda Rezeli, Paul A. Wadsworth, Ákos Végvári, Frederick F. Lang, György Marko-Varga, Gillian C. Lynch, Erik P. Sulman, Ekaterina Mostovenko, Carol L. Nilsson, Cheryl F. Lichti, Qianghu Wang
Publikováno v:
Journal of Proteome Research
Novel proteoforms with single amino acid variations represent proteins that often have altered biological functions but are less explored in the human proteome. We have developed an approach, searching high quality shotgun proteomic data against an e
Publikováno v:
Biopolymers. 99:448-459
Factor VIII (FVIII) is the blood coagulation protein which when defective or deficient causes for hemophilia A, a severe hereditary bleeding disorder. Activated FVIII (FVIIIa) is the cofactor to the serine protease factor IXa (FIXa) within the membra
Publikováno v:
The Journal of Physical Chemistry B. 115:547-556
We calculate the water and ion spatial distributions around charged oligonucleotides using a renormalized three-dimensional reference interaction site theory coupled with the HNC closure. Our goal is to understand the balance between inter-DNA strand
Publikováno v:
Protein Science. 19:1011-1022
The transfer model implying additivity of the peptide backbone free energy of transfer is computationally tested. Molecular dynamics simulations are used to determine the extent of change in transfer free energy (ΔGtr) with increase in chain length
Publikováno v:
The Journal of Physical Chemistry B. 113:9472-9478
The capability to manipulate proteins/peptide fragments at liquid-solid interfaces has led to tremendous applications in detectors and biotechnology. Therefore, understanding the detailed molecular behavior of proteins and peptides tethered on a hard
Autor:
Matthew A. Franchek, Kirill V. Larin, Gillian C. Lynch, X. Zhang, Pradeep Sharma, S. Anandampillai
Publikováno v:
Computer Methods in Applied Mechanics and Engineering. 197:3378-3385
In recent years, quantum dots have generated enormous interest from the life sciences community due to their (largely) untapped potential in biomedical applications; particularly in bio-labeling and sensing. While empirical work already exists on the
Autor:
Donald G. Truhlar, Yuri L. Volobuev, Ronald J. Duchovic, Thomas C. Allison, Bruce C. Garrett, Albert F. Wagner, José C. Corchado, Gillian C. Lynch
Publikováno v:
Computer Physics Communications. 156:319-322
Program summary Program Title: POTLIB 2001, version 1.0 Catalogue identifier: ADPJ Program summary URL: http://cpc.cs.qub.ac.uk/summaries/ADPJ Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland