Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Gillian C, Lowe"'
Autor:
Samantha J. Montague, Christopher W. Smith, Clare S. Lodwick, Charlotte Stoneley, Matthew Roberts, Gillian C. Lowe, William A. Lester, Steve P. Watson, Phillip L. R. Nicolson
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 3, Pp n/a-n/a (2022)
Abstract Background Anti‐platelet factor 4 (PF4) antibodies that activate platelets via FcγRIIA drive the pathophysiology of vaccine‐induced immune thrombocytopenia and thrombosis (VITT). Evolution of these antibodies and their ability to activa
Externí odkaz:
https://doaj.org/article/66bf351f0ec74913826ce427be977694
Autor:
Gillian C. Lowe, Roksana Fickowska, Rashid Al Ghaithi, Annabel Maclachlan, Paul Harrison, Will Lester, Steve P. Watson, Bethan Myers, Justin Clark, Neil V. Morgan
Publikováno v:
Platelets, Vol 30, Iss 1, Pp 56-65 (2019)
Heavy menstrual bleeding (HMB) is often undiagnosed in women and can cause discomfort and distress. A haemostatic cause for excessive bleeding is often not routinely investigated and can lead to hysterectomy at an early age. A prospective cohort stud
Externí odkaz:
https://doaj.org/article/d11bdd4c9d984438a723af57a7ee7b04
Autor:
Abdullah O. Khan, Annabel Maclachlan, Gillian C. Lowe, Phillip L.R. Nicolson, Rashid Al Ghaithi, Steven G. Thomas, Steve P. Watson, Jeremy A. Pike, Neil V. Morgan
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/841b56189aed4bee91ddf86401a6496e
Autor:
John-Paul Westwood, Mari Thomas, Ferras Alwan, Vickie McDonald, Sylvia Benjamin, William A. Lester, Gillian C. Lowe, Tina Dutt, Quentin A. Hill, Marie Scully
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1159-1166 (2017)
Abstract: Acute antibody-mediated thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy with high morbidity and mortality. Rituximab is highly effective as prophylaxis in patients at risk of acute TTP relapse, but the ideal dosing
Externí odkaz:
https://doaj.org/article/039675966e174eba8bed33687e100d8d
Autor:
Ben Johnson, Gillian C. Lowe, Jane Futterer, Marie Lordkipanidzé, David MacDonald, Michael A. Simpson, Isabel Sanchez-Guiú, Sian Drake, Danai Bem, Vincenzo Leo, Sarah J. Fletcher, Ban Dawood, José Rivera, David Allsup, Tina Biss, Paula HB Bolton-Maggs, Peter Collins, Nicola Curry, Charlotte Grimley, Beki James, Mike Makris, Jayashree Motwani, Sue Pavord, Katherine Talks, Jecko Thachil, Jonathan Wilde, Mike Williams, Paul Harrison, Paul Gissen, Stuart Mundell, Andrew Mumford, Martina E. Daly, Steve P. Watson, Neil V. Morgan
Publikováno v:
Haematologica, Vol 101, Iss 10 (2016)
Inherited thrombocytopenias are a heterogeneous group of disorders characterized by abnormally low platelet counts which can be associated with abnormal bleeding. Next-generation sequencing has previously been employed in these disorders for the conf
Externí odkaz:
https://doaj.org/article/832905450f7e4e20b9fb9ac64c324ba8
Autor:
Michael Makris, Jecko Thachil, Michael Laffan, Drew Provan, Michael F. Murphy, Sue Pavord, Quentin A. Hill, Beverley J. Hunt, John D. Grainger, Gillian C. Lowe, Adrian C. Newland
Publikováno v:
British Journal of Haematology
Summary This document aims to provide practical guidance for the assessment and management of patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP), during the COVID‐19 pandemic. The intention is to support clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eea0afda73e04e4e59581b235663c7d
https://doi.org/10.1111/bjh.16775
https://doi.org/10.1111/bjh.16775
Autor:
Samantha J. Montague, Christopher W. Smith, Clare S. Lodwick, Charlotte Stoneley, Matthew Roberts, Gillian C. Lowe, William A. Lester, Steve P. Watson, Phillip L.R. Nicolson
Publikováno v:
Research and practice in thrombosis and haemostasis. 6(3)
Anti-platelet factor 4 (PF4) antibodies that activate platelets via FcγRIIA drive the pathophysiology of vaccine-induced immune thrombocytopenia and thrombosis (VITT). Evolution of these antibodies and their ability to activate platelets after initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb68f7f759da5f9f2b88f19ac7d0e92
https://pubmed.ncbi.nlm.nih.gov/35515079
https://pubmed.ncbi.nlm.nih.gov/35515079
Autor:
Julia Anderson, Sean Platton, Peter J. Baker, Keith Gomez, Ian Jennings, Tina T. Biss, Gillian C. Lowe
Publikováno v:
British journal of haematologyReferences. 195(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70da29a87e5bbabb47b0f034871e1ea7
https://pubmed.ncbi.nlm.nih.gov/34494258
https://pubmed.ncbi.nlm.nih.gov/34494258
Autor:
Charlotte Stoneley, Phillip L R Nicolson, Christopher W Smith, William Lester, Matthew Roberts, Gillian C. Lowe, Samantha J. Montague, Clare S Lodwick, Steve P. Watson
BackgroundAnti-Platelet Factor 4 (PF4) IgG antibodies that activate platelets via FcγRIIa have been shown to be an important part of the pathophysiology of vaccine-induced immune thrombocytopenia and thrombosis (VITT). There is now extensive literat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813a2203948b67b51c257a6ec187294a
https://doi.org/10.1101/2021.08.17.21262138
https://doi.org/10.1101/2021.08.17.21262138
Autor:
Gillian C. Lowe, Steven G. Thomas, Amanda Dalby, Paul Harrison, Yotis A. Senis, Steve P. Watson, Phillip L R Nicolson, Sam Kemble
Circulating large “preplatelets” undergo fission via barbell platelet intermediates into two smaller, mature platelets. In this study, we determine whether preplatelets and/or barbells are equivalent to reticulated/immature platelets by using Ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09f82f27b10ca1da31251a81eb4167f
https://doi.org/10.1101/2021.07.30.454421
https://doi.org/10.1101/2021.07.30.454421