Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gillian, Blancke"'
Autor:
Ioanna Petta, Marie Thorp, Maarten Ciers, Gillian Blancke, Louis Boon, Tim Meese, Filip Van Nieuwerburgh, Andy Wullaert, Richard Grencis, Dirk Elewaut, Geert van Loo, Lars Vereecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundProtective immunity against intestinal helminths requires induction of robust type-2 immunity orchestrated by various cellular and soluble effectors which promote goblet cell hyperplasia, mucus production, epithelial proliferation, and smoo
Externí odkaz:
https://doaj.org/article/4430a9dec9a04b37b1e9e9b55eb09f9c
Autor:
Lien Verboom, Christopher J. Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi S. Ravichandran, Lars Vereecke, Geert van Loo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-13 (2023)
Abstract The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues. In inflammatory bowel disease (IBD) in humans, as well as in experimenta
Externí odkaz:
https://doaj.org/article/7eadb0df90114b9c9cc7180ab08eeb46
Autor:
Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, Tino Hochepied, Christian Vanhove, Eric Gracey, Emilie Dumas, Teddy Manuelo, Ivan Josipovic, Geert vanLoo, Dirk Elewaut, Lars Vereecke
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Arthritis is the most common extra‐intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shar
Externí odkaz:
https://doaj.org/article/6cc505e181ba4edfa275d745f425476b
Autor:
Sofie Martens, Nozomi Takahashi, Gillian Blancke, Niels Vandamme, Hanne Verschuere, Tatyana Divert, Marnik Vuylsteke, Geert Berx, Peter Vandenabeele
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract Cancers acquire several capabilities to survive the multistep process in carcinogenesis. Resisting cell death is one of them. Silencing of the necroptosis initiator Ripk3 occurs in a wide variety of cancer types including melanoma. Little is
Externí odkaz:
https://doaj.org/article/77587f1f6b4b4d57a3677719136c1aaf
Autor:
Bart Neyns, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Modulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg populatio
Externí odkaz:
https://doaj.org/article/f3b73327b159432399d5c58c01682dd6
Autor:
Victor H. Villar, Maria Francesca Allega, Ruhi Deshmukh, Tobias Ackermann, Mark A. Nakasone, Johan Vande Voorde, Thomas M. Drake, Janina Oetjen, Algernon Bloom, Colin Nixon, Miryam Müller, Stephanie May, Ee Hong Tan, Lars Vereecke, Maude Jans, Gillian Blancke, Daniel J. Murphy, Danny T. Huang, David Y. Lewis, Thomas G. Bird, Owen J. Sansom, Karen Blyth, David Sumpton, Saverio Tardito
Publikováno v:
NATURE CHEMICAL BIOLOGY
Villar, V H, Allega, M F, Deshmukh, R, Ackermann, T, Nakasone, M A, Voorde, J V, Drake, T, Oetjen, J, Bloom, A, Nixon, C, Vereecke, L, Jans, M, Blancke, G, Bird, T G, Lewis, D, Sansom, O J, Blyth, K, Sumpton, D & Tardito, S 2022, ' Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer ', Nature Chemical Biology . https://doi.org/10.1038/s41589-022-01154-9
Villar, V H, Allega, M F, Deshmukh, R, Ackermann, T, Nakasone, M A, Voorde, J V, Drake, T, Oetjen, J, Bloom, A, Nixon, C, Vereecke, L, Jans, M, Blancke, G, Bird, T G, Lewis, D, Sansom, O J, Blyth, K, Sumpton, D & Tardito, S 2022, ' Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer ', Nature Chemical Biology . https://doi.org/10.1038/s41589-022-01154-9
Glutamine synthetase (GS) activity is conserved from prokaryotes to humans, where the ATP-dependent production of glutamine from glutamate and ammonia is essential for neurotransmission and ammonia detoxification. Here, we show that mammalian GS uses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d644a6f88baef6ab2fcb6f68543200e9
https://doi.org/10.1038/s41589-022-01154-9
https://doi.org/10.1038/s41589-022-01154-9
Autor:
Richard de Reuver, Simon Verdonck, Evelien Dierick, Josephine Nemegeer, Eline Hessmann, Sadeem Ahmad, Maude Jans, Gillian Blancke, Filip Van Nieuwerburgh, Alexander Botzki, Lars Vereecke, Geert van Loo, Wim Declercq, Sun Hur, Peter Vandenabeele, Jonathan Maelfait
Publikováno v:
NATURE
The RNA-editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) limits the accumulation of endogenous immunostimulatory double-stranded RNA (dsRNA)(.) In humans, reduced ADAR1 activity causes the severe inflammatory disease Aicardi-Goutieres syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bc1b7d4ce863a53860735b7d60899a
https://doi.org/10.1038/s41586-022-04974-w
https://doi.org/10.1038/s41586-022-04974-w
Autor:
Geert Berx, Yvan Saeys, Philippe Tummers, Bart N. Lambrecht, Koen Van de Vijver, Hannelore Denys, Steven Weyers, Jo Van Dorpe, Ruth Seurinck, Kevin Verstaen, Sofie De Prijck, Kelly Lemeire, Steven Goossens, Sven Jonckheere, Gillian Blancke, Kato De Clercq, Joachim Taminau, Jordy De Coninck, Niels Vandamme, Nele Loret
High-grade serous ovarian cancer (HGSOC) is responsible for the largest number of ovarian cancer deaths. The frequent therapy-resistant relapses necessitate a better understanding of mechanisms driving therapy resistance. Therefore, we mapped more th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15007e53a992021f57aea94c220574dc
https://doi.org/10.1158/1541-7786.c.6545409.v1
https://doi.org/10.1158/1541-7786.c.6545409.v1
Autor:
Geert Berx, Yvan Saeys, Philippe Tummers, Bart N. Lambrecht, Koen Van de Vijver, Hannelore Denys, Steven Weyers, Jo Van Dorpe, Ruth Seurinck, Kevin Verstaen, Sofie De Prijck, Kelly Lemeire, Steven Goossens, Sven Jonckheere, Gillian Blancke, Kato De Clercq, Joachim Taminau, Jordy De Coninck, Niels Vandamme, Nele Loret
Supplementary Figure from Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d5c2ac2657e8e2e88a32608dfe6cca
https://doi.org/10.1158/1541-7786.22527378.v1
https://doi.org/10.1158/1541-7786.22527378.v1
Autor:
Geert Berx, Yvan Saeys, Philippe Tummers, Bart N. Lambrecht, Koen Van de Vijver, Hannelore Denys, Steven Weyers, Jo Van Dorpe, Ruth Seurinck, Kevin Verstaen, Sofie De Prijck, Kelly Lemeire, Steven Goossens, Sven Jonckheere, Gillian Blancke, Kato De Clercq, Joachim Taminau, Jordy De Coninck, Niels Vandamme, Nele Loret
Supplementary Table from Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187eccd1d50e8f336e3ff79095dff82e
https://doi.org/10.1158/1541-7786.22527372
https://doi.org/10.1158/1541-7786.22527372