Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Gilles Sauve"'
Publikováno v:
Revue Forestière Française, Vol 74, Iss 2 (2023)
Les forêts dans la région Grand Est représentent un enjeu économique et territorial considérable. Les dépérissements subis par ces forêts depuis 2018 ont décimé des milliers d’hectares et concernent la plupart des essences présentes, à
Externí odkaz:
https://doaj.org/article/1aa9b571caa54438860afa9019c74ed6
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1509-1513
A screening assay program on HIV-protease was carried out on more than fifty commercially available N-protected amino acids and has revealed that those with a long side chain such as lysine, ornithine and arginine exhibited significant inhibition of
Publikováno v:
AAPS PharmSci. 4:34-44
We have evaluated the specificity and the variation in activity against human immunodeficiency virus (HIV) infection of antisense oligodeoxynucleotides (ODNs) with regard to factors such as dose-response range, number and choice of experimental contr
Autor:
Gilles Sauve, Abderrahim Bouzide
Publikováno v:
Tetrahedron Letters. 43:1961-1964
N-Acyl-β-aminoalcohols were obtained efficiently via a highly endocyclic cleavage of N-acyloxazolidinones mediated by sodium azide in methanol at 40°C.
Publikováno v:
Analytical Biochemistry. 284:169-172
Autor:
Gilles Sauve, Abderrahim Bouzide
Publikováno v:
Tetrahedron Letters. 38:5945-5948
Treatment of symmetrical diol with Ag 2 O and alkyl halide gave the monoprotected derivative in good to excellent yield.
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 14:421-428
The structure of acetyl-pepstatin has been investigated in solution by two-dimensional NMR spectroscopy and molecular modeling. The analysis of DQFCOSY, TOCSY and NOESY spectra lead to a full assignment of the -NMR signals both in DMSO-d6 and in TFE-
Publikováno v:
Journal of Enzyme Inhibition. 9:217-233
The inhibitory behavior of simple N-protected amino acids containing a dysfunctional enol group was analyzed. Pseudo-Hill coefficients below 0.5 were obtained for the enol compounds. The active moiety of the enols described herein is involved in an e
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:343-355
A series of enol HIV-1 protease inhibitors which show competitive inhibition and the structure-activity relationship study which led to the design of these compounds are reported. By systematically modifying simple amino acids, Boc-Phe enol and Boc-T
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:619-624
A methodology for the specific site incorporation of thioamide linkages into a growing peptide under mild conditions using thioacylating agent 1 is described. Thus, the synthesis of the four monothioanalogues of thymopentin (TP-5): [Valt4]- 18, [Aspt