Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gilles S. van Tienderen"'
Autor:
Kimberley Ober, Floris J.M. Roos, Gilles S. van Tienderen, Kübra Köten, Annelot Klaassen, Wunan Mi, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102431- (2023)
Summary: Bile ducts are essential for bile transport and consist of complex branching tubular networks. Human patient-derived cholangiocyte develops a cystic rather than branching duct morphology. Here, we present a protocol to establish branching mo
Externí odkaz:
https://doaj.org/article/84a4580cad5643e5aaecc2b8f27e89c6
Autor:
Gilles S. van Tienderen, Marije E. A. van Beek, Ivo J. Schurink, Oskar Rosmark, Henk P. Roest, Jantine Tieleman, Jeroen Demmers, Iain Muntz, James Conboy, Gunilla Westergren-Thorsson, Gijsje Koenderink, Luc JW van der Laan, Monique M. A. Verstegen
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Cholangiocarcinoma (CCA) is a type of liver cancer with an aggressive phenotype and dismal outcome in patients. The metastasis of CCA cancer cells to distant organs, commonly lung and lymph nodes, drastically reduces overall survival. However, mechan
Externí odkaz:
https://doaj.org/article/c5fdd88c25154968aee0ea46f6da7c1e
Autor:
Gilles S. van Tienderen, Jorke Willemse, Bas van Loo, Eline V. A. van Hengel, Jeroen de Jonge, Luc J. W. van der Laan, Jeroen Leijten, Monique M. A. Verstegen
Publikováno v:
Cells, Vol 11, Iss 22, p 3657 (2022)
Advances in biomaterials, particularly in combination with encapsulation strategies, have provided excellent opportunities to increase reproducibility and standardization for cell culture applications. Herein, hybrid microcapsules are produced in a f
Externí odkaz:
https://doaj.org/article/5faab3788a1b42398cbc800d1170178b
Autor:
Gilles S van Tienderen, Oskar Rosmark, Ruby Lieshout, Jorke Willemse, Floor de Weijer, Linda Elowsson Rendin, Gunilla Westergren-Thorsson, Michail Doukas, Bas Groot Koerkamp, Martin E van Royen, Luc JW van der Laan, Monique MA Verstegen
Publikováno v:
Acta Biomaterialia, 158, 115-131. Elsevier
Patient-derived tumor organoids have been established as promising tools for in vitro modelling of multiple tumors, including cholangiocarcinoma (CCA). However, organoids are commonly cultured in basement membrane extract (BME) which does not recapit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449c27609dd5f77df951c7d0a695e416
https://doi.org/10.1016/j.actbio.2022.11.038
https://doi.org/10.1016/j.actbio.2022.11.038
Autor:
Gilles S. van Tienderen, Ling Li, Laura Broutier, Yoshimasa Saito, Patricia Inacio, Meritxell Huch, Florin M. Selaru, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
Cancer Cell, 40(3), 226-230. Cell Press
Reliable establishment of tumor organoids is paramount to advance applications of organoid technology for personalized medicine. Here, we share our multi-center experience on initiation and tumorigenic confirmation of hepatobiliary cancer organoids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bcd4e7c7be6a2c13b9648ec71a6b72
https://doi.org/10.1016/j.ccell.2022.02.001
https://doi.org/10.1016/j.ccell.2022.02.001
Autor:
Floris J.M. Roos, Gilles S. van Tienderen, Haoyu Wu, Ignacio Bordeu, Dina Vinke, Laura Muñoz Albarinos, Kathryn Monfils, Sabrah Niesten, Ron Smits, Jorke Willemse, Oskar Rosmark, Gunilla Westergren-Thorsson, Daniel J. Kunz, Maurice de Wit, Pim J. French, Ludovic Vallier, Jan N.M. IJzermans, Richard Bartfai, Hendrik Marks, Ben D. Simons, Martin E. van Royen, Monique M.A. Verstegen, Luc J.W. van der Laan
Publikováno v:
Cell Stem Cell, 29, 5, pp. 776-794
Cell Stem Cell, 29(5), 776-794.e13. Cell Press
Cell Stem Cell, 29, 776-794
Cell Stem Cell, 29(5), 776-794.e13. Cell Press
Cell Stem Cell, 29, 776-794
Human cholangiocyte organoids show great promise for regenerative therapies and in vitro modeling of bile duct development and diseases. However, the cystic organoids lack the branching morphology of intrahepatic bile ducts (IHBDs). Here, we report e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4a78da49405cec33445247405f73c2
Autor:
Gilles S. van Tienderen, James Conboy, Iain Muntz, Jorke Willemse, Jantine Tieleman, Kathryn Monfils, Ivo J. Schurink, Jeroen A.A. Demmers, Michail Doukas, Gijsje H. Koenderink, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
Biomaterials Advances, 146
Biomaterials Advances, 146:213289. Elsevier Ltd.
Biomaterials Advances, 146:213289. Elsevier Ltd.
Tumor initiation and progression are critically dependent on interaction of cancer cells with their cellular and extracellular microenvironment. Alterations in the composition, integrity, and mechanical properties of the extracellular matrix (ECM) di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798ce8e4500b3bb0d820f3e58075b01d
http://resolver.tudelft.nl/uuid:57a7a46f-b889-4ee4-acf1-c5910d81eee4
http://resolver.tudelft.nl/uuid:57a7a46f-b889-4ee4-acf1-c5910d81eee4
Autor:
Guoying Zhou, Ruby Lieshout, Gilles S. van Tienderen, Valeska de Ruiter, Martin E. van Royen, Patrick P. C. Boor, Luc Magré, Jyaysi Desai, Kübra Köten, Yik Yang Kan, Zhouhong Ge, Lucia Campos Carrascosa, Cecile Geuijen, Dave Sprengers, Luc J. W. van der Laan, Monique M. A. Verstegen, Jaap Kwekkeboom
Publikováno v:
British Journal of Cancer, 127(4), 649-660. Nature Publishing Group
Background Immunotherapy with immune checkpoint inhibitors (ICIs) is being explored to improve cholangiocarcinoma (CCA) therapy. However, it remains difficult to predict which ICI will be effective for individual patients. Therefore, the aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5340ce172736b9d215c163420c585b2d
https://pure.eur.nl/en/publications/ff7205ea-851c-4c52-af5e-7b7ea9523b03
https://pure.eur.nl/en/publications/ff7205ea-851c-4c52-af5e-7b7ea9523b03
Autor:
Ruby Lieshout, Chen Chen, Natalia Sánchez-Romero, Kerstin Schneeberger, Iris Pla Palacin, Louis C. Penning, Joery De Kock, Hans Clevers, Sabine A. Fuchs, Bart Spee, Monique E van Wolferen, Loes A Oosterhoff, Haaike Colemonts-Vroninks, Imre F. Schene, Ruurdtje Hoekstra, Pedro M. Baptista, Shicheng Ye, Luc J. W. van der Laan, Monique M A Verstegen, Gilles S van Tienderen, Frank G. van Steenbeek
Publikováno v:
Hepatology, 72(1), 257-270. John Wiley & Sons Ltd.
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Hepatology (Baltimore, Md.)
Hepatology
Hepatology. American Association for the Study of Liver Diseases (AASLD)
Hepatology (Baltimore, Md.), 72(1), 257-270. John Wiley and Sons Ltd
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Hepatology (Baltimore, Md.)
Hepatology
Hepatology. American Association for the Study of Liver Diseases (AASLD)
Hepatology (Baltimore, Md.), 72(1), 257-270. John Wiley and Sons Ltd
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Background and Aims: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)–positive adult stem cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fad3b8a1076fd1098e69342ff04b7e7
https://doi.org/10.1002/hep.31037
https://doi.org/10.1002/hep.31037
Autor:
Luc J. W. van der Laan, Monique M A Verstegen, Jan N. M. IJzermans, Bas Groot Koerkamp, Gilles S van Tienderen
Publikováno v:
Cancers
Cancers, Vol 11, Iss 11, p 1706 (2019)
Cancers, 11(11):1706. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, Vol 11, Iss 11, p 1706 (2019)
Cancers, 11(11):1706. Multidisciplinary Digital Publishing Institute (MDPI)
Primary liver cancer, consisting predominantly of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), remains one of the most lethal malignancies worldwide. This high malignancy is related to the complex and dynamic interactions between tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49a34e56e9b05d1ba28eb708cd63651
https://doi.org/10.3390/cancers11111706
https://doi.org/10.3390/cancers11111706