Microwave promoted C–O coupling for synthesizing O-aryloxytriazole nucleoside analogues

Autor: Mei Cong, Juan L. Iovanna, Laurence Borge, Yi Xia, Palma Rocchi, Ling Peng, Jingjie Tang, Gilles Quéléver

Publikováno v: New Journal of Chemistry. 39:3889-3893

Synthetic nucleoside analogues with novel structural entities are of considerable importance in the search for new structural paradigms with biologically interesting activities. We report in this work that microwave promoted C–O coupling reaction i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae6285d73b8571744152b13f6255e844
https://doi.org/10.1039/c4nj02284j

Structural characterization of poly(amino)ester dendrimers and related impurities by electrospray tandem mass spectrometry

Autor: Laurence Charles, Valérie Monnier, Rémi Giordanengo, Gilles Quéléver, Ling Peng, Camille Bouillon, Aura Tintaru

Publikováno v: Rapid Communications in Mass Spectrometry. 24:2207-2216

An acid-terminated poly(amino)ester dendrimer was studied by electrospray ionization tandem mass spectrometry to establish its fragmentation pathways, with the aim of using them to investigate the structure of any defective molecules generated during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3d9ad7f8977e3815171e84983bef645
https://doi.org/10.1002/rcm.4628

1,1′-Xylyl bis-1,4,8,11-tetraaza cyclotetradecane: A new potential copper chelator agent for neuroprotection in Alzheimer’s disease. Its comparative effects with clioquinol on rat brain copper distribution

Autor: Jean-Chrétien Norreel, Jean-Louis Kraus, Gilles Quéléver, Younes Laras, Bernard Mallet, Amandine Rolland, Cédrik Garino, Vincent Moret, Nicolas Pietrancosta

Publikováno v: HAL
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2006, 16, pp.3298-3301
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2006, 16, pp.3298-3301
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (12), pp.3298-3301. ⟨10.1016/j.bmcl.2006.03.026⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2006, 16 (12), pp.3298-3301. ⟨10.1016/j.bmcl.2006.03.026⟩

Dysfunction of copper metabolism leading to its excess or deficiency results in severe ailments. Recently, neurodegenerative disorders such as Alzheimer’s disease have been associated with copper metabolism. Compounds having the ability to reduce c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf55f9bbb52ddc43ab7e522f31a77d4
https://doi.org/10.1016/j.bmcl.2006.03.026

Parallel synthesis of new phenylalanino-2-(phenylthio)pyrrolidin-3-one scaffold-based analogues

Autor: M. Bouygues, Gilles Quéléver, Jean Louis Kraus

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :1181-1189

Based on the specific PhePro proteolytic cleavage of the HIV-protease, we synthesized short pseudopeptides incorporating a 2-(phenylthio)pyrrolidin-3-one ring. We previously described various analogues based on this scaffold. We report herein a paral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc97046909457da5029ce75af497c31e
https://doi.org/10.1039/b201147f

ChemInform Abstract: C-S Coupling Using a Mixed-Ligand Pd Catalyst: A Highly Effective Strategy for Synthesizing Arylthio-Substituted Heterocycles

Autor: Fanqi Qu, Gilles Quéléver, Yuting Fan, Ling Peng, Yi Xia, Mei Cong, Yang Liu, Jean-Manuel Raimundo

Publikováno v: ChemInform. 45

For the first time a mixed-ligand system, which can also activate C—Cl bonds in heteroaryl rings for C—S bond formation, is used in the title reaction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85da0aef77b4d2ac502b580b79000b2e
https://doi.org/10.1002/chin.201420127