Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gilles P.M. Borrelly"'
Autor:
Nigel J. Robinson, Gilles P.M. Borrelly, Simone Ciofi-Baffoni, Xun-Cheng Su, Lucia Banci, Ivano Bertini
Publikováno v:
Journal of Biological Chemistry. 279:27502-27510
The Atx1 copper metallochaperone from Synechocystis PCC 6803, ScAtx1, interacts with two P(1)-type copper ATPases to supply copper proteins within intracellular compartments, avoiding ATPases for other metals en route. Here we report NMR-derived solu
Publikováno v:
Molecular Microbiology. 53:217-227
Zn(2+)-responsive repressor ZiaR and Co(2+)-responsive activator CoaR modulate production of P(1)-type Zn(2+)- (ZiaA) and Co(2+)- (CoaT) ATPases respectively. What dictates metal selectivity? We show that Delta ziaDeltacoa double mutants had similar
Autor:
Gilles P.M. Borrelly, Stephen E. J. Rigby, Helen K. Leech, Peter Heathcote, Evelyne Raux, Kirsty J. McLean, Dieter Jahn, Martin J. Warren, Nigel J. Robinson, Andrew W. Munro, Marco Malten
Publikováno v:
Journal of Biological Chemistry. 278:41900-41907
CbiX is a cobaltochelatase required for the biosynthesis of vitamin B12 and is found in Archaea as a short form (CbiXS containing 120-145 amino acids) and in some bacteria as a longer version (CbiXL containing 300-350 amino acids). Purification of ei
Autor:
Margaret A. Kihlken, Jennifer S. Cavet, Nick E. Le Brun, Gilles P.M. Borrelly, Colin R. Harwood, David S. Radford
Publikováno v:
FEMS Microbiology Letters. 220:105-112
The structure of the hypothetical copper-metallochaperone CopZ from Bacillus subtilis and its predicted partner CopA have been studied but their respective contributions to copper export, -import, -sequestration and -supply are unknown. DeltacopA was
Autor:
Mark D. Harrison, Simon K. Whitehall, Samuel G. Cox, Gilles P.M. Borrelly, Andrea K. Robinson, Nigel J. Robinson
Publikováno v:
Journal of Biological Chemistry. 277:30394-30400
Homeostatic mechanisms prevent the accumulation of free zinc in the cytoplasm, raising questions regarding where surplus zinc is stored and how it is delivered to and from these stores. A genetic screen for zinc hypersensitivity in Schizosaccharomyce
Autor:
Gilles P.M. Borrelly, Ralf Schmid, Peter J. Sadler, Nigel J. Robinson, Clive S. Butler, Claudia A. Blindauer, Ian Harvey, Chris E. Cooper
Publikováno v:
The Biochemical journal. 378(Pt 2)
The thylakoid lumen of the cyanobacterium Synechocystis PCC 6803 is supplied with copper via two copper-transporting ATPases and a metallochaperone intermediary. We show that the copper site of this metallochaperone is unusual and consists of two cys
Publikováno v:
FEMS microbiology reviews. 27(2-3)
Homeostatic systems for essential and non-essential metals create the cellular environments in which the correct metals are acquired by metalloproteins while the incorrect ones are somehow avoided. Cyanobacteria have metal requirements often absent f
Autor:
Peter R. Rich, Gilles P.M. Borrelly, Stephen Tottey, Nigel J. Robinson, Pamela J. Robinson, Sabine A.M. Rondet
Publikováno v:
The Journal of biological chemistry. 277(7)
A bacterial two-hybrid assay revealed interaction between a protein now designated bacterial Atx1 and amino-terminal domains of copper-transporting ATPases CtaA (cellular import) and PacS (thylakoid import) but not the related zinc (ZiaA) or cobalt (
Autor:
Gilles P.M. Borrelly, Ralf Schmid, Claudia A. Blindauer, Nigel J. Robinson, Peter J. Sadler, Mark D. Harrison
Publikováno v:
Journal of Inorganic Biochemistry. 96:102