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Akademický článek

In Vivo Imaging of Apoptosis in Oncology: An Update

Autor: Christel Vangestel, Marc Peeters, Gilles Mees, Ruth Oltenfreiter, Hendrikus H. Boersma, Philip H. Elsinga, Chris Reutelingsperger, Nancy Van Damme, Bart De Spiegeleer, Christophe Van de Wiele

Publikováno v: Molecular Imaging, Vol 10 (2011)

In this review, data on noninvasive imaging of apoptosis in oncology are reviewed. Imaging data available are presented in order of occurrence in time of enzymatic and morphologic events occurring during apoptosis. Available studies suggest that vari

Externí odkaz: https://doaj.org/article/67308971883f4308b18d05042c9638d2

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Tc-99m-Labeled Tricarbonyl His-CNA35 as an Imaging Agent for the Detection of Tumor Vasculature

Autor: Christophe Van de Wiele, Yves D'Asseler, Kathelijne Peremans, Chris P. M. Reutelingsperger, Nancy Van Damme, Magali Van Steenkiste, Simon Vermeire, Koen Mertens, Gilles Mees, Rudi Dierckx

Publikováno v: Journal of Nuclear Medicine, 53(3), 464-471. SOC NUCLEAR MEDICINE INC
Journal of Nuclear Medicine, 53(3), 464-471. Society of Nuclear Medicine and Molecular Imaging

Given the importance of angiogenesis for a tumor's survival and growth, several therapeutic strategies rely on the selective inhibition of angiogenesis and the destruction of existing tumor vasculature. These strategies raise the need for a noninvasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775fb29a0caf4513efb90f8137df088b
https://doi.org/10.2967/jnumed.111.095794

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Single-Photon Emission Computed Tomographic Imaging of the Early Time Course of Therapy-Induced Cell Death Using Technetium 99m Tricarbonyl His-Annexin A5 in a Colorectal Cancer Xenograft Model

Autor: Christophe Van de Wiele, Christel Vangestel, Nancy Van Damme, Steven Staelens, Patrick Pauwels, Chris P. M. Reutelingsperger, Koen Mertens, Marc Peeters, Gilles Mees

Publikováno v: Molecular Imaging, 11(2), 135-147. Decker Publishing
Molecular imaging
Molecular imaging, 11(2), 135-147
Molecular Imaging, Vol 11 (2012)

As apoptosis occurs over an interval of time after administration of apoptosis-inducing therapy in tumors, the changes in technetium 99m (99mTc)-tricarbonyl (CO)3 His-annexin A5 (His-ann A5) accumulation over time were examined. Colo205-bearing mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287f94f6dc41b35ffd59fbf3a454cf62
https://cris.maastrichtuniversity.nl/en/publications/c6a0a7f8-f59d-4f52-bcbf-8e72a0804b87

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[18F]FDG PET/CT for the assessment of the volume of the spleen

Autor: Peter, Smeets, Gilles, Mees, Hamphrey, Ham, Alex, Maes, Koenraad, Verstraete, Christophe, Van De Wiele

Publikováno v: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 60(1)

The aim of this study was to report on the feasibility and accuracy of spleen volume determination on FDG PET/CT imaging using region growing and the CT part of the PET/CT examination as anatomical landmark (PET-CT based spleen volume method PBM) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81b3aecabcf2ed5868cbc70356c75caa
https://pubmed.ncbi.nlm.nih.gov/26672630

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Metabolic correlates of tumour hypoxia in malignant canine mammary carcinoma

Autor: B. Van Goethem, Kathelijne Peremans, H. de Rooster, R. Ducatelle, Rudi Dierckx, Christel Vangestel, C. Van de Wiele, Gilles Mees, S. Loomans, Patrick Pauwels, N. Van Damme

Publikováno v: Research in Veterinary Science. 91:e125-e128

Given its importance in human and canine tumour biology, a profound understanding of tumour hypoxia is of paramount importance. Therefore, the aim of this work was to investigate the relationship between tumour hypoxia and the expression of a number

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f64bf603f3308bb699c7580299a05aa
https://doi.org/10.1016/j.rvsc.2011.01.014

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Editorial (Thematic Issue: Personalized Medicine in Oncology, the Potential Role of Nuclear Medicine Imaging)

Autor: Christophe Van de Wiele, Gilles Mees

Publikováno v: Current Pharmaceutical Design. 20:2231-2233

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7583ac3eb12c056fa1e3d3cc4b4b172
https://doi.org/10.2174/13816128113196660669

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Forcing Cancer Cells to Commit Suicide

Autor: Christophe Van de Wiele, Christel Vangestel, Marc Peeters, Gilles Mees

Publikováno v: CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS. 24(4):395-407

Apoptosis plays a crucial role in the normal development, homeostasis of multicellular organisms, carcinogenic process, and response of cancer cells to anticancer drugs. It is a genetically strictly regulated process, controlled by the balance betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695eeab0e2fdc8d0637c20b397347ddf
https://doi.org/10.1089/cbr.2008.0598

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Molecular imaging of hypoxia with radiolabelled agents

Autor: Christophe Van De Wiele, Christel Vangestel, Gilles Mees, Rudi Dierckx

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging

Tissue hypoxia results from an inadequate supply of oxygen (O(2)) that compromises biological functions. Structural and functional abnormalities of the tumour vasculature together with altered diffusion conditions inside the tumour seem to be the mai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89725923b5827bffe1f9d386037a809d
https://doi.org/10.1007/s00259-009-1195-9

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