Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts.

Autor: Gilles M Leclerc, Guy J Leclerc, Jeffim N Kuznetsov, Joanna DeSalvo, Julio C Barredo

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e74420 (2013)

The outcome of patients with resistant phenotypes of acute lymphoblastic leukemia (ALL) or those who relapse remains poor. We investigated the mechanism of cell death induced by metformin in Bp- and T-ALL cell models and primary cells, and show that

Externí odkaz: https://doaj.org/article/fb5938589d304fcdb719320ab64fac0f

All-optical sampling and magnification based on XPM-induced focusing

Autor: Nuno, J., Gilles, M., Guasoni, M., Finot, C., Fatome, J.

We theoretically and experimentally investigate the design of an all-optical noiseless magnification and sampling function free from any active gain medium and associated high-power continuous wave pump source. The proposed technique is based on the

Externí odkaz: http://arxiv.org/abs/1607.04970

Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema

Autor: Herth, F.J.F., Gompelmann, D., Schuhmann, M., Eberhardt, R., Harzheim, D., Rump, B., Slebos, D.J., Ten Hacken, N., Klooster, K., Hartman, J.E., Augustijn, S., Shah, P.L., Caneja, C., McNulty, W., Garner, J., Deslée, G., Vallerand, H., Dury, S., Gras, D., Verdier, M., Marquette, C.H., Sanfiorenzo, C., Clary, C., Leheron, C., Pradelli, J., Korzeniewski, S., Wolter, P., Arfi, T., Macone, F., Poudenx, M., Leroy, S., Guillemart, A., Griffonet, J., Strange, C., Argula, R., Silvestri, G., Huggins, J.T., Pastis, N., Woodford, D., Schwarz, L., Walker, D., Criner, G., Mamary, J., Marchetti, N., Desai, P., Shenoy, K., Garfield, J.L., Travaline, J., Criner, H., Srivastava-Malhotra, S., Tauch, V., Maxfield, R., Brenner, K., Bulman, W., Whippo, B.A., Jellen, P.A., Kalhan, R., Gillespie, C.T., Rosenberg, S., McAvoy DeCamp, M., Rogowski, A.S., Hixon, J., Angel, L.F., Dib, O., Sciurba, F.C., Chandra, D., Crespo, M., Field, J. Bon, Tedrow, J. Rahul, Ledezma, C., Consolaro, P., Beckner, M., Majid, A., Cheng, G., Cardenas-Garcia, J., Beach, D., Folch, E., Agnew, A., Hori, W., Nathanson, A., Wahidi, M., Shofer, S., Hartwig, M., Mahmood, K., Smathers, E., Tillis, W., Verma, K., Taneja, D., Peil, M., Chittivelu, S., Doloszycki, P., Whitten, P.E., Aulakh, B., Ikadios, O., Michel, J., Crabb, J., McVay, B., Scott, A., Pautler, E.A., Connolly, T.A., Santacruz, J.F., Kopas, L., Parham, R., Solid, B., Krimsky, W., Gregoire, F., King, S., Mehta, A., Almeida, F., Gildea, T., Cicenia, J., Machuzak, M., Sethi, S., Meli, Y.M., Baran, J., Rice, R., Faile, D., Rai, N., Jensen, K., Kahlstrom, R., Haroon, A., Ionita, R., White, F., Watkins, D., Moore, B., Soukiasian, H., Merry, H., Mosenifar, Z., Ghandehari, S., Balfe, D., Park, J., Mardirosian, R., Ferguson, J.S., Kanne, J., Sonetti, D., Modi, D., Regan, M., Maloney, J., Hackbarth, M., Gilles, M., Harris, A., Maser, A., Puchalski, J.T., Rochester, C., Possick, J., Johnson, K., Dabre, Z., Kovitz, K., Joo, M., DeLisa, J., Villalan, S.V., Krishna, G., Canfield, J., Marfatia, A., Selley, E., Utz, J., Midthun, D., Kern, R., Edell, E.S., Boras (née Kosok), L.L., Gay, S., Bauman, K.A., King Han, M., Sagana, R.L., Nelson, K., Meldrum, C., Jantz, M., Mehta, H.J., Eagan, C., West, J., Delage, A., Martel, S., LeBlanc, P., Maltais, F., Lacasse, Y., Lampron, N., Laberge, F., Milot, J., Picard, J., Breton, M.J., Dransfield, M., Wells, J.M., Bhatt, S., Smith, P., Seabron-Harris, E.N., Hammond, K., Egidio, C., Slebos, Dirk-Jan, Cicenia, Joseph, Sciurba, Frank C., Criner, Gerard J., Hartman, Jorine E., Garner, Justin, Deslée, Gaëtan, Delage, Antoine, Jantz, Michael, Marquette, Charles-Hugo, Strange, Charlie, Hatipoglu, Umur, Mehta, Atul C., LaPrad, Adam S., Schmid-Bindert, Gerald, Herth, Felix J.F., Shah, Pallav L.

Publikováno v: In Chest May 2019 155(5):928-937

Ocean crustal veins record dynamic interplay between plate-cooling-induced cracking and ocean chemistry

Autor: Evans, Aled D., Coggon, Rosalind M., Harris, Michelle, Carter, Elliot J., Albers, Elmar, Guérin, Gilles M., Belgrano, Thomas M., Jonnalagadda, Mallika, Grant, Lewis J.C., Kempton, Pamela D., Sanderson, David J., Milton, James A., Henstock, Timothy J., Alt, Jeff C., Teagle, Damon A.H.

Publikováno v: In Earth and Planetary Science Letters 15 January 2025 650

THE GREEN OCEAN AMAZON EXPERIMENT (GOAMAZON2014/5) OBSERVES POLLUTION AFFECTING GASES, AEROSOLS, CLOUDS, AND RAINFALL OVER THE RAIN FOREST

Autor: Martin, S. T., Artaxo, P., Machado, L., Manzi, A. O., Souza, R. A. F., Schumacher, C., Wang, J., Biscaro, T., Brito, J., Calheiros, A., Jardine, K., Medeiros, A., Portela, B., de Sá, S. S., Adachi, K., Aiken, A. C., Albrecht, R., Alexander, L., Andreae, M. O., Barbosa, H. M. J., Buseck, P., Chand, D., Comstock, J. M., Day, D. A., Dubey, M., Fan, J., Fast, J., Fisch, G., Fortner, E., Giangrande, S., Gilles, M., Goldstein, A. H., Guenther, A., Hubbe, J., Jensen, M., Jimenez, J. L., Keutsch, F. N., Kim, S., Kuang, C., Laskin, A., McKinney, K., Mei, F., Miller, M., Nascimento, R., Pauliquevis, T., Pekour, M., Peres, J., Petäjä, T., Pöhlker, C., Pöschl, U., Rizzo, L., Schmid, B., Shilling, J. E., Dias, M. A. Silva, Smith, J. N., Tomlinson, J. M., Tóta, J., Wendisch, M.

Publikováno v: Bulletin of the American Meteorological Society, 2017 May 01. 98(5), 981-998.

Externí odkaz: https://www.jstor.org/stable/26243736