Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Gilles Kaplanski"'
Autor:
Audrey Cambon, Charlotte Rebelle, Richard Bachelier, Laurent Arnaud, Stéphane Robert, Marie Lagarde, Romain Muller, Edwige Tellier, Yéter Kara, Aurélie Leroyer, Catherine Farnarier, Loris Vallier, Corinne Chareyre, Karine Retornaz, Anne-Laure Jurquet, Tu-Anh Tran, Romaric Lacroix, Françoise Dignat-George, Gilles Kaplanski
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveIL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA). Leukocyte microvesi
Externí odkaz:
https://doaj.org/article/ff2d2c95d2b743a68a3fa2aad6e86172
Autor:
Robin Arcani, Louise Rey, Alice Mazziotto, Daniel Bertin, Gilles Kaplanski, Pierre-André Jarrot, Pierre Lafforgue, Geoffroy Venton, Xavier Heim, Patrick Villani, Jean-Louis Mège, Alexandre Brodovitch, Nathalie Bardin
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-9 (2023)
Abstract Background Anti-Jo-1 autoantibodies represent essential markers in the diagnosis of antisynthetase syndrome (ASS). In this retrospective study, we aimed to investigate whether their concentrations and fluctuations could both respectively ref
Externí odkaz:
https://doaj.org/article/06fbc7f5842245c2b3f6405f5b864165
Autor:
Robin Arcani, Florian Correard, Pierre Suchon, Gilles Kaplanski, Rodolphe Jean, Raphael Cauchois, Marine Leprince, Vincent Arcani, Julie Seguier, Benjamin De Sainte Marie, Baptiste Andre, Marie Koubi, Pascal Rossi, Stéphane Gayet, Nirvina Gobin, Victoria Garrido, Joris Weiland, Elisabeth Jouve, Anne-Laure Couderc, Patrick Villani, Aurélie Daumas
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTocilizumab and anakinra are anti-interleukin drugs to treat severe coronavirus disease 2019 (COVID-19) refractory to corticosteroids. However, no studies compared the efficacy of tocilizumab versus anakinra to guide the choice of the thera
Externí odkaz:
https://doaj.org/article/4fc10343fb484f138e16cd6442659fb8
Autor:
Pierre-André Jarrot, Adrien Mirouse, Sébastien Ottaviani, Simon Cadiou, Jean-Hugues Salmon, Eric Liozon, Simon Parreau, Martin Michaud, Benjamin Terrier, Pierre-Edouard Gavand, Ludovic Trefond, Virginie Lavoiepierre, Jeremy Keraen, Daniel Rekassa, Bastien Bouldoires, Thierry Weitten, Damien Roche, Antoine Poulet, Caroline Charpin, Vincent Grobost, Marion Hermet, Magali Pallure, Chloe Wackenheim, Ludovic Karkowski, Pierre Grumet, Thomas Rogier, Nabil Belkefi, Vincent Pestre, Emilie Broquet, Amélie Leurs, Sophie Gautier, Valérie Gras, Pierre Gilet, Jan Holubar, Nadia Sivova, Nicolas Schleinitz, Jean-Marc Durand, Brice Castel, Alexandre Petrier, Robin Arcani, Baptiste Gramont, Philippe Guilpain, Hubert Lepidi, Pierre-Jean Weiller, Joelle Micallef, David Saadoun, Gilles Kaplanski
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTWe conducted a national in-depth analysis including pharmacovigilance reports and clinical study to assess the reporting rate (RR) and to determine the clinical profile of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in COVID-1
Externí odkaz:
https://doaj.org/article/970ddb7d49c04bd4a900d1b8a0d87da2
Autor:
Edwige Tellier, Agnès Widemann, Raphaël Cauchois, Julien Faccini, Marie Lagarde, Marion Brun, Philippe Robert, Stéphane Robert, Richard Bachelier, Pascale Poullin, Elien Roose, Karen Vanhoorelbeke, Paul Coppo, Françoise Dignat-George, Gilles Kaplanski
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by a severe ADAMTS13 deficiency due to the presence of anti-ADAMTS13 auto-antibodies, with subsequent accumulation of circulating ultra-large von Willebrand factor (VWF) mult
Externí odkaz:
https://doaj.org/article/268edbcaee32430189336f9989489db4
Autor:
Adrien Joseph, Martin Eloit, Elie Azoulay, Gilles Kaplanski, François Provot, Claire Presne, Alain Wynckel, Steven Grangé, Éric Rondeau, Frédéric Pène, Yahsou Delmas, Alexandre Lautrette, Christelle Barbet, Christiane Mousson, Jean‐Philippe Coindre, Pierre Perez, Matthieu Jamme, Jean‐François Augusto, Pascale Poullin, Frédéric Jacobs, Khalil El Karoui, Cécile Vigneau, Marc Ulrich, Tarik Kanouni, Moglie Le Quintrec, Mohamed Hamidou, Simon Ville, Anne Charvet‐Rumpler, Mario Ojeda‐Uribe, Pascal Godmer, Véronique Fremeaux‐Bacchi, Agnès Veyradier, Jean‐Michel Halimi, Paul Coppo
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Background The prevalence, prognostic role, and diagnostic value of blood pressure in immune‐mediated thrombotic thrombocytopenic purpura (iTTP) and other thrombotic microangiopathies (TMAs) remain unclear. Methods Using a national cohort
Externí odkaz:
https://doaj.org/article/0bd0757c396849008e228ac2e5bc41be
Autor:
Isabelle Kone-Paut, Stéphane Barete, Bahram Bodaghi, Kumaran Deiva, Anne-Claire Desbois, Caroline Galeotti, Julien Gaudric, Gilles Kaplanski, Alfred Mahr, Nicolas Noel, Maryam Piram, Tu-Anh Tran, Bertrand Wechsler, David Saadoun, Collaborators
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss S1, Pp 1-28 (2021)
Abstract Behçet’s disease (BD) is a systemic variable vessel vasculitis that involves the skin, mucosa, joints, eyes, arteries, veins, nervous system and gastrointestinal system, presenting with remissions and exacerbations. It is a multifactorial
Externí odkaz:
https://doaj.org/article/320c5431755b47ffad08c83cf89a4879
Autor:
Raphael Cauchois, Romain Muller, Marie Lagarde, Françoise Dignat-George, Edwige Tellier, Gilles Kaplanski
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 3, p 758 (2023)
Thrombotic thrombocytopenic purpura (TTP) is a severe thrombotic microangiopathy. The current pathophysiologic paradigm suggests that the ADAMTS13 deficiency leads to Ultra Large-Von Willebrand Factor multimers accumulation with generation of dissemi
Externí odkaz:
https://doaj.org/article/1bd4f232b91947baa9b51b1f085de2a2
Autor:
Raphael Cauchois, Lea Pietri, Jean-Baptiste Dalmas, Marie Koubi, Thibaut Capron, Nadim Cassir, Nicola Potere, Ildo Polidoro, Rodolphe Jean, Pierre-André Jarrot, Baptiste Andre, Veronique Veit, Julien Carvelli, Vanessa Pauly, Pascal Chanez, Laurent Papazian, Gilles Kaplanski
Publikováno v:
Microorganisms, Vol 10, Iss 12, p 2423 (2022)
During SARS-CoV-2 infection, eosinopenia may reflect a hyperactive immune response. In this study of hospitalized COVID-19 patients, we aimed to better understand the prognostic value of severe eosinopenia (absolute eosinophil count = 0 G/L) and deci
Externí odkaz:
https://doaj.org/article/ab3dfe0a2b6748a29cdd63416d094d0a
Autor:
Kadri Kangro, Elien Roose, An‐Sofie Schelpe, Edwige Tellier, Gilles Kaplanski, Jan Voorberg, Simon F. De Meyer, Andres Männik, Karen Vanhoorelbeke
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 918-930 (2020)
Abstract Background In immune‐mediated thrombotic thrombocytopenic purpura (iTTP), patients develop an immune response against the multidomain enzyme ADAMTS13. ADAMTS13 consists of a metalloprotease (M) and disintegrin‐like (D) domain, 8 thrombos
Externí odkaz:
https://doaj.org/article/1b08d655e5664beab1e9d966ee70984e