Výsledky vyhledávání - "Gilles H. Tapolsky"

Abstract 4437: BXQ-350: A novel biologic with an innovative mechanism of action targeting sphingolipid metabolism that induces cancer cell death and repolarizes the tumor microenvironment

Autor: Gilles H. Tapolsky, Tim Stephens, Nikhil Wilkins, Robin Furnish, Charlie Cruze, Ray Takigiku

Publikováno v: Cancer Research. 83:4437-4437

Background: Antineoplastic agents seem to affect tumors by targeting cancer cells via cytotoxic mechanism (traditional cytotoxic agents), an oncogenic pathway that promotes cancer cells proliferation (targeted agents), or immune pathways that are dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::adea2e29bb829df7e77e36afdb109a3b
https://doi.org/10.1158/1538-7445.am2023-4437

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Abstract 3042: BXQ-350 may protect peripheral nerves from the direct cytotoxicity of chemotherapeutic agents leading to chemotherapy induced peripheral neuropathy

Autor: Nikhil Wilkins, Tim Stephens, Robin Furnish, Charlie Cruze, Darren Wolfe, Gilles H. Tapolsky, Ray Takigiku

Publikováno v: Cancer Research. 83:3042-3042

Background: Chemotherapy Induced Peripheral Neuropathy (CIPN) is a debilitating side effect associated with many antineoplastic chemotherapeutic agents including cytotoxic and targeted agents. It significantly impacts cancer patients’ quality of li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c74b76e09a2164140792ad82488c69b0
https://doi.org/10.1158/1538-7445.am2023-3042

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Radiolabeling of magnetic particles with rhenium-188 for cancer therapy

Autor: Gayle J.T. Pauer, Sarah Nicole Failing, Gilles H. Tapolsky, Urs O. Häfeli

Publikováno v: Journal of Magnetism and Magnetic Materials. 225:73-78

A one-step radiolabeling procedure of highly magnetic particles with the therapeutic -emitter rhenium-188 (Re) has been developed. Magnetic targeted carriers (MTCs) are composites of metallic iron and activated carbon that can be labeled in the prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d91fa07e4645bc21fddf9e9a317ebca5
https://doi.org/10.1016/s0304-8853(00)01230-0

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Radiolabeling of magnetic targeted carriers (MTC) with indium-111

Autor: Gilles H. Tapolsky, Junfeng Yu, Li Yuhua, Urs O. Häfeli, Farhad Farudi

Publikováno v: Nuclear medicine and biology. 30(7)

Magnetic targeted carriers (MTC) are magnetically susceptible microparticles that can be physically targeted to a specific site. MTC were radiolabeled with In-111 using three different methods. Reaction parameters were investigated in order to optimi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef1da1ca09336919eb69110d4a8c418
https://pubmed.ncbi.nlm.nih.gov/14499335

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