Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Gilles Fischer"'
Autor:
Pablo Villarreal, Samuel O'Donnell, Nicolas Agier, Felipe Muñoz-Guzman, Jose Benavides-Parra, Kami Urbina, Tomas A. Peña, Mark Solomon, Roberto F. Nespolo, Gilles Fischer, Cristian Varela, Francisco A. Cubillos
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTEvaluating domestication signatures beyond model organisms is essential for a thorough understanding of the genotype-phenotype relationship in wild and human-related environments. Structural variations (SVs) can significantly impact phenotype
Externí odkaz:
https://doaj.org/article/5d0e55c2cb304d0ca70fbbb52bba6c72
Autor:
Wladimir Mardones, Carlos A. Villarroel, Kristoffer Krogerus, Sebastian M. Tapia, Kamila Urbina, Christian I. Oporto, Samuel O’Donnell, Romain Minebois, Roberto Nespolo, Gilles Fischer, Amparo Querol, Brian Gibson, Francisco A. Cubillos
Publikováno v:
Microbial Biotechnology, Vol 13, Iss 4, Pp 1012-1025 (2020)
Summary The utilization of S. eubayanus has recently become a topic of interest due to the novel organoleptic properties imparted to beer. However, the utilization of S. eubayanus in brewing requires the comprehension of the mechanisms that underlie
Externí odkaz:
https://doaj.org/article/d883f1aae91544d59315f6c909b09899
Autor:
Rossana Droghetti, Nicolas Agier, Gilles Fischer, Marco Gherardi, Marco Cosentino Lagomarsino
Publikováno v:
eLife, Vol 10 (2021)
Recent results comparing the temporal program of genome replication of yeast species belonging to the Lachancea clade support the scenario that the evolution of the replication timing program could be mainly driven by correlated acquisition and loss
Externí odkaz:
https://doaj.org/article/b85398afda6848d58207bec082e4d85b
Autor:
Héloïse Muller, Vittore F Scolari, Nicolas Agier, Aurèle Piazza, Agnès Thierry, Guillaume Mercy, Stéphane Descorps‐Declere, Luciana Lazar‐Stefanita, Olivier Espeli, Bertrand Llorente, Gilles Fischer, Julien Mozziconacci, Romain Koszul
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 7, Pp 1-19 (2018)
Abstract In chromosome conformation capture experiments (Hi‐C), the accuracy with which contacts are detected varies due to the uneven distribution of restriction sites along genomes. In addition, repeated sequences or homologous regions remain ind
Externí odkaz:
https://doaj.org/article/49438d1599934cefa4a3b55153b9a263
Autor:
Nicolas Agier, Stéphane Delmas, Qing Zhang, Aubin Fleiss, Yan Jaszczyszyn, Erwin van Dijk, Claude Thermes, Martin Weigt, Marco Cosentino-Lagomarsino, Gilles Fischer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Temporal programs of genome replication show different levels of conservation between closely or distantly related species. Here, the authors generate genome-wide replication timing profiles for ten yeast species, and analyze their evolutionary dynam
Externí odkaz:
https://doaj.org/article/f394fafe14464009957b771ab49d4e78
Autor:
Aubin Fleiss, Samuel O'Donnell, Téo Fournier, Wenqing Lu, Nicolas Agier, Stéphane Delmas, Joseph Schacherer, Gilles Fischer
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008332 (2019)
Genome engineering is a powerful approach to study how chromosomal architecture impacts phenotypes. However, quantifying the fitness impact of translocations independently from the confounding effect of base substitutions has so far remained challeng
Externí odkaz:
https://doaj.org/article/26b5802e9fd0491c954331f99f9a0b68
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92621 (2014)
Reconstructing synteny blocks is an essential step in comparative genomics studies. Different methods were already developed to answer various needs such as genome (re-)annotation, identification of duplicated regions and whole genome duplication eve
Externí odkaz:
https://doaj.org/article/a33fdd96c2994c96b6ea219b5cb4014c
Publikováno v:
PLoS Genetics, Vol 4, Iss 9, p e1000175 (2008)
The propensity of segmental duplications (SDs) to promote genomic instability is of increasing interest since their involvement in numerous human genomic diseases and cancers was revealed. However, the mechanism(s) responsible for their appearance re
Externí odkaz:
https://doaj.org/article/7c250aa4b18e46f0aada660b5525390d
Publikováno v:
PLoS Genetics, Vol 2, Iss 3, p e32 (2006)
Hemiascomycete yeasts cover an evolutionary span comparable to that of the entire phylum of chordates. Since this group currently contains the largest number of complete genome sequences it presents unique opportunities to understand the evolution of
Externí odkaz:
https://doaj.org/article/9a5130573e524aeab71ad548fe31a512
Autor:
Pablo Villarreal, Carlos A. Villarroel, Sam O'Donnell, Nicolas Agier, Julian F. Quintero‐Galvis, Tomas A. Peña, Roberto F. Nespolo, Gilles Fischer, Cristian Varela, Francisco A. Cubillos
Publikováno v:
Environmental Microbiology. 24:5615-5629
Most organisms belonging to the Saccharomycotina subphylum have high genetic diversity and a vast repertoire of metabolisms and lifestyles. Lachancea cidri is an ideal yeast model for exploring the interplay between genetics, ecological function and