Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Gilles Fillion"'
Publikováno v:
Behavioural Brain Research. 158:339-348
5-HT-moduline is an endogenous tetrapeptide, which acts specifically as an antagonist of 5-HT1B auto- and heteroreceptors. HG1 is an ethyl arylmethyloxypiperidine acetate and an antagonist of 5-HT-moduline, which has no 5-HT-moduline agonist effect.
Autor:
Jacques Lambrozo, Magali Kochanek, Jean-Marc Bailly, O. Massot, B. Grimaldi, Francois Deschamps, Gilles Fillion
Publikováno v:
Brain Research. 858:143-150
It was previously suggested that exposure to magnetic fields (MFs) could generate dysfunction of the CNS. The physiological manifestations described lead us to postulate that these symptoms might be related to a dysfunction of the serotonergic system
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 359:40-47
The effect of the selective r5-HT1B agonist 3-(1,2,5,6-tetrahydro)-4-pyridil-5-pyrrolo [3,2-b] pyril-5-one (CP93,129) on the K(+)-evoked overflow of [3H]dopamine was studied in rat striatal synaptosomes loaded with [3H]dopamine. The aim of the study
Autor:
Jean-Claude Rousselle, O. Massot, Jean-Michel Reymann, Hervé Allain, Michel Bourin, Danièle Bentué-Ferrer, Gilles Fillion
Publikováno v:
European Journal of Pharmacology. 358:129-137
5-Hydroxytryptamine-moduline (5-HT-moduline) is an endogenous tetrapeptide (Leu-Ser-Ala-Leu) recently isolated and characterized from mammalian brain. This compound interacts with 5-HT1B receptors as a non-competitive, high-affinity antagonist and ha
Autor:
Hala Sarhan, Gilles Fillion
Publikováno v:
CNS Spectrums. 3:50-58
The endogenous peptide 5-HT–moduline has been characterized as a novel neuropeptide that binds to 5-HT1B receptors in the brain areas in which it is released. By inducing structural changes in these receptors, this peptide prevents 5-HT binding, th
Autor:
Lena Edelman, Gilles Fillion, Ana Cardona, Jean-Claude Rousselle, O. Massot, Isabelle Cloëz-Tayarani
Publikováno v:
Proceedings of the National Academy of Sciences. 94:9899-9904
5-HT-moduline is an endogenous tetrapeptide [Leu-Ser-Ala-Leu (LSAL)] that was first isolated from bovine brain tissue. To understand the physiological role of this tetrapeptide, we studied the localization of 5-HT-moduline binding sites in rat and mo
Publikováno v:
Brain Research Protocols. 1:145-151
The interleukin-1 family of polypeptides (IL-1 alpha, IL-1 beta and IL-1 receptor antagonist (RA)) induces various centrally mediated host defense responses to infectious pathogens. Considerable interest has focussed on IL-1 as a mediator in disease
Autor:
M.P. Fillion, Gilles Fillion, Abderrahim Merzak, Geoffrey J. Pilkington, Shahriar Koochekpour
Publikováno v:
Molecular Brain Research. 41:1-7
Expression of seven serotonin or 5-hydroxytryptamine (5-HT) receptors (5-HT1D alpha, 5-HT1E, 5-HT2, 5-HT1A, 5-HT1C, 5-HT1D beta, and 5-HT6) was investigated in human normal fetal astrocytes and eight glioma cell lines by reverse transcription and pol
Publikováno v:
Journal of Neuroimmunology. 66:65-70
The expression of transcripts for Interleukin-1 (IL-1) type I and type II receptors (IL-1R1, IL-1R2) was investigated in the mouse brain and spleen using reverse transcription-polymerase chain reaction techniques under basal conditions and following
Publikováno v:
Molecular Brain Research. 36:337-342
In situ hybridization with a 5-HT 1B receptor probe and immunocytochemistry with γ-aminobutyric acid (GABA) antibody performed on adjacent sections of rat brains reveal that GABAergic cell bodies, which represent 10–15% of the cellular population,