Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Gilles Edan"'
Autor:
Chadia Ed‐driouch, Florent Chéneau, Françoise Simon, Guillaume Pasquier, Benoit Combès, Anne Kerbrat, Emmanuelle Le Page, Sophie Limou, Nicolas Vince, David‐Axel Laplaud, Franck Mars, Cédric Dumas, Gilles Edan, Pierre‐Antoine Gourraud
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 12, Pp 1863-1873 (2022)
Abstract Objective Multiple sclerosis (MS) is a multifactorial disease with increasingly complicated management. Our objective is to use on‐demand computational power to address the challenges of dynamically managing MS. Methods A phase 3 clinical
Externí odkaz:
https://doaj.org/article/3aa3aa89d1a642b69c94ddff9b8613b1
Autor:
Audrey Gauthier, Sébastien Viel, Magali Perret, Guillaume Brocard, Romain Casey, Christine Lombard, Sabine Laurent‐Chabalier, Marc Debouverie, Gilles Edan, Sandra Vukusic, Christine Lebrun‐Frénay, Jérôme De Sèze, David Axel Laplaud, Giovanni Castelnovo, Olivier Gout, Aurélie Ruet, Thibault Moreau, Olivier Casez, Pierre Clavelou, Eric Berger, Hélène Zephir, Sophie Trouillet‐Assant, Eric Thouvenot, OFSEP Investigators
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 5, Pp 1141-1150 (2021)
Abstract We compared SimoaTM and EllaTM immunoassays to assess serum neurofilament‐light chain levels in 203 multiple sclerosis patients from the OFSEP HD study. There was a strong correlation (ρ = 0.86, p
Externí odkaz:
https://doaj.org/article/065e81b4c5174e9fa867174580f930de
Autor:
Katline Metzger-Peter, Laurent Daniel Kremer, Gilles Edan, Paulo Loureiro De Sousa, Julien Lamy, Dominique Bagnard, Ayikoe-Guy Mensah-Nyagan, Thibault Tricard, Guillaume Mathey, Marc Debouverie, Eric Berger, Anne Kerbrat, Nicolas Meyer, Jérôme De Seze, Nicolas Collongues
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Central nervous system damage in multiple sclerosis (MS) is responsible for serious deficiencies. Current therapies are focused on the treatment of inflammation; however, there is an urgent need for innovative therapies promoting
Externí odkaz:
https://doaj.org/article/b37de76ed73045908c261ab84e917929
Autor:
Olivier Commowick, Michaël Kain, Romain Casey, Roxana Ameli, Jean-Christophe Ferré, Anne Kerbrat, Thomas Tourdias, Frédéric Cervenansky, Sorina Camarasu-Pop, Tristan Glatard, Sandra Vukusic, Gilles Edan, Christian Barillot, Michel Dojat, Francois Cotton
Publikováno v:
NeuroImage, Vol 244, Iss , Pp 118589- (2021)
MRI plays a crucial role in multiple sclerosis diagnostic and patient follow-up. In particular, the delineation of T2-FLAIR hyperintense lesions is crucial although mostly performed manually - a tedious task. Many methods have thus been proposed to a
Externí odkaz:
https://doaj.org/article/b1a128cbc9dd4283a9f90ceb94aa775c
Autor:
Benoit Combès, Anne Kerbrat, Guillaume Pasquier, Olivier Commowick, Brandon Le Bon, Francesca Galassi, Philippe L'Hostis, Nora El Graoui, Raphael Chouteau, Emmanuel Cordonnier, Gilles Edan, Jean-Christophe Ferré
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Over the last 10 years, the number of approved disease modifying drugs acting on the focal inflammatory process in Multiple Sclerosis (MS) has increased from 3 to 10. This wide choice offers the opportunity of a personalized medicine with the objecti
Externí odkaz:
https://doaj.org/article/44bef6c2faaa4449b0f2c5ea53b26411
Autor:
Laura Couloume, Juliette Ferrant, Simon Le Gallou, Marion Mandon, Rachel Jean, Nadège Bescher, Helene Zephir, Gilles Edan, Eric Thouvenot, Aurelie Ruet, Marc Debouverie, Karin Tarte, Patricia Amé, Mikael Roussel, Laure Michel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple sclerosis (MS) is an immune-driven demyelinating disease of the central nervous system. Immune cell features are particularly promising as predictive biomarkers due to their central role in the pathogenesis but also as drug targets, even if
Externí odkaz:
https://doaj.org/article/bc2d8e837ec74af998627a4cd8b329ab
Publikováno v:
International Journal of Health Geographics, Vol 16, Iss 1, Pp 1-6 (2017)
Abstract Background Despite intensive research over several decades, the etiology of multiple sclerosis (MS) remains poorly understood, although environmental factors are supposedly implicated. Our goal was to identify spatial clusters of MS incident
Externí odkaz:
https://doaj.org/article/86a9faaba89a422ab3d6a6c1cd553cc9
Autor:
Diane Pivot, Marc Debouverie, Michel Grzebyk, David Brassat, Michel Clanet, Pierre Clavelou, Christian Confavreux, Gilles Edan, Emmanuelle Leray, Thibault Moreau, Sandra Vukusic, Guy Hédelin, Francis Guillemin
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167556 (2016)
INTRODUCTION:Geographical variation in the prevalence of multiple sclerosis (MS) is controversial. Heterogeneity is important to acknowledge to adapt the provision of care within the healthcare system. We aimed to investigate differences in prevalenc
Externí odkaz:
https://doaj.org/article/c5b6bb48956640f09950478e85957853
Autor:
Emmanuelle Leray, Sandra Vukusic, Marc Debouverie, Michel Clanet, Bruno Brochet, Jérôme de Sèze, Hélène Zéphir, Gilles Defer, Christine Lebrun-Frenay, Thibault Moreau, Pierre Clavelou, Jean Pelletier, Eric Berger, Philippe Cabre, Jean-Philippe Camdessanché, Shoshannah Kalson-Ray, Christian Confavreux, Gilles Edan
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132033 (2015)
Recent studies in multiple sclerosis (MS) showed longer survival times from clinical onset than older hospital-based series. However estimated median time ranges widely, from 24 to 45 years, which makes huge difference for patients as this neurologic
Externí odkaz:
https://doaj.org/article/a80a4d29282b411ab004686834748e47
Autor:
Alessandro Crimi, Olivier Commowick, Adil Maarouf, Jean-Christophe Ferré, Elise Bannier, Ayman Tourbah, Isabelle Berry, Jean-Philippe Ranjeva, Gilles Edan, Christian Barillot
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93024 (2014)
ObjectivesA novel characterization of Clinically Isolated Syndrome (CIS) patients according to lesion patterns is proposed. More specifically, patients are classified according to the nature of inflammatory lesions patterns. It is expected that this
Externí odkaz:
https://doaj.org/article/147bda123f8f490693590fbeea6b9082