Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gilles D. Tamagnan"'
Autor:
Shu-Ying Liu, Hong-Wen Qiao, Tian-Bin Song, Xiu-Lin Liu, Yun-Xia Yao, Chun-Song Zhao, Olivier Barret, Sheng-Li Xu, Yan-Ning Cai, Gilles D. Tamagnan, Vesna Sossi, Jie Lu, Piu Chan
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract Background Abnormal activation of immune system is an important pathogenesis of Parkinson’s disease, but the relationship between peripheral inflammation, central microglia activation and dopaminergic degeneration remains unclear. Objectiv
Externí odkaz:
https://doaj.org/article/c609bd1c3e0b4251b727768e1d66d36a
Autor:
Xiu-Lin Liu, Shu-Ying Liu, Olivier Barret, Gilles D. Tamagnan, Hong-Wen Qiao, Tian-Bin Song, Jie Lu, Piu Chan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/e65c623fb3164ad5b1f7c73bd6dbee87
Autor:
Xiu-Lin Liu, Shu-Ying Liu, Olivier Barret, Gilles D. Tamagnan, Hong-Wen Qiao, Tian-Bin Song, Jie Lu, Piu Chan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Background18F-FP-DTBZ has been proven as a biomarker for quantifying the concentration of presynaptic vesicular monoamine transporter 2 (VMAT2). However, its clinical application is still limited.ObjectivesTo evaluate the difference in dopaminergic i
Externí odkaz:
https://doaj.org/article/f8db20daab86445891682b2ebdb49ae6
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The advent of preclinical research scanners for in vivo imaging of small animals has added confidence into the multi-step decision-making process of radiotracer discovery and development. Furthermore, it has expanded the utility of imaging techniques
Externí odkaz:
https://doaj.org/article/7211be439beb423f9f52f92ed7ebf502
Autor:
Olivier, Barret, David, Alagille, Sandra, Sanabria, Robert A, Comley, Robby M, Weimer, Edilio, Borroni, Mark, Mintun, Nicholas, Seneca, Caroline, Papin, Thomas, Morley, Ken, Marek, John P, Seibyl, Gilles D, Tamagnan, Danna, Jennings
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e52a1ed416996cef33d80eeee500e565
https://pubmed.ncbi.nlm.nih.gov/27908967
https://pubmed.ncbi.nlm.nih.gov/27908967
Autor:
David, Thomae, Thomas J, Morley, Hsiaoju S, Lee, Olivier, Barret, Cristian, Constantinescu, Caroline, Papin, Ronald M, Baldwin, Gilles D, Tamagnan, David, Alagille
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 59(5)
Phosphodiesterase (PDE) 4 is the most prevalent PDE in the central nervous system (CNS) and catalyzes hydrolysis of intracellular cAMP, a secondary messenger. By therapeutic inhibition of PDE4, intracellular cAMP levels can be stabilized, and the sym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b27d29866063eff6d133d129bd1f98f0
https://pubmed.ncbi.nlm.nih.gov/27006107
https://pubmed.ncbi.nlm.nih.gov/27006107
Autor:
Adriana Alexandre S, Tavares, Fabien, Caillé, Olivier, Barret, Caroline, Papin, Hsiaoju, Lee, Thomas J, Morley, Krista, Fowles, Daniel, Holden, John P, Seibyl, David, Alagille, Gilles D, Tamagnan
Publikováno v:
Nuclear medicine and biology. 41(5)
A new radiotracer for imaging the serotonin 4 receptors (5-HT4) in brain, [¹⁸F]MNI-698, was recently developed by our group. Evaluation in nonhuman primates indicates the novel radiotracer holds promise as an imaging agent of 5-HT4 in brain. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::308fcbe60e8711e61c49c3a40e36f8bd
https://pubmed.ncbi.nlm.nih.gov/24674817
https://pubmed.ncbi.nlm.nih.gov/24674817
Autor:
David, Alagille, Herve, DaCosta, Yelin, Chen, Kamondanai, Hemstapat, Alice, Rodriguez, Ronald M, Baldwin, P Jeffrey, Conn, Jeffrey P, Conn, Gilles D, Tamagnan
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(11)
We report the synthesis of four series of 3,5-disubstituted-phenyl ligands targeting the metabotropic glutamate receptor subtype 5: (2-methylthiazol-4-yl)ethynyl (1a–j,), (6-methylpyridin-2-yl)ethynyl (2a–j), (5-methylpyridin-2-yl)ethynyl (3a–j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd6cde2085cb57bcc9c427568d8c6d3
https://pubmed.ncbi.nlm.nih.gov/21546249
https://pubmed.ncbi.nlm.nih.gov/21546249
Autor:
Julie K, Staley, Christopher H, van Dyck, David, Weinzimmer, Eric, Brenner, Ronald M, Baldwin, Gilles D, Tamagnan, Patrizia, Riccardi, Effie, Mitsis, John P, Seibyl
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 46(9)
(123)I-5-IA-85380 ((123)I-5-IA; [(123)I]-5-iodo-3-[2(S)-azetidinylmethoxy]pyridine) is a promising SPECT radiotracer for imaging beta(2)-containing nicotinic acetylcholine receptors (beta(2)-nAChRs) in brain. Beta(2)-nAChRs are the initial site of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf6d61eee4837d5b55a0dc94e123201a
https://pubmed.ncbi.nlm.nih.gov/16157529
https://pubmed.ncbi.nlm.nih.gov/16157529
Autor:
Fanxing Zeng, Jiyoung Mun, Nachwa Jarkas, Jeffrey S. Stehouwer, Ronald J. Voll, Gilles D. Tamagnan, Leonard Howell, John R. Votaw, Clinton D. Kilts, Charles B. Nemeroff, Mark M. Goodman
Publikováno v:
Journal of Medicinal Chemistry; Jan2009, Vol. 52 Issue 1, p62-73, 12p