Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Gilles Benichou"'
Autor:
Alexandre G. Lellouch, Alec R. Andrews, Gaelle Saviane, Zhi Yang Ng, Ilse M. Schol, Marion Goutard, Amon-Ra Gama, Ivy A. Rosales, Robert B. Colvin, Laurent A. Lantieri, Mark A. Randolph, Gilles Benichou, Curtis L. Cetrulo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundVascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is associated with significant morbidity. Induction of immune tolerance of VCAs would permit
Externí odkaz:
https://doaj.org/article/9edd525b71754b0d840e1d03aaddef28
TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
Autor:
François Cherbonneau, Guoping Li, Priyanka Gokulnath, Parul Sahu, Aurore Prunevieille, Robert Kitchen, Gilles Benichou, Jérôme Larghero, Ibrahim Domian, Saumya Das
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103806- (2022)
Summary: Dynamic profiling of changes in gene expression in response to stressors in specific microenvironments without requiring cellular destruction remains challenging. Current methodologies that seek to interrogate gene expression at a molecular
Externí odkaz:
https://doaj.org/article/844b4fa23be2421cb3296c5036bba01f
Autor:
Wiebke Sommer, MD, Jane M. O, MD, Kurt B. Pruner, BSc, Abbas Dehnadi, DVM, Kyu Ha Huh, MD, Kortney A. Robinson, MD, Isabel Hanekamp, PhD, Ivy Rosales, MD, Alison S. Bean, BSc, Josh Paster, BSc, Tetsu Oura, MD, Rex Neal Smith, MD, Robert Colvin, MD, Gilles Benichou, PhD, Tatsuo Kawai, MD, Joren C. Madsen, MD, DPhil, James S. Allan, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 6, p e705 (2021)
Background. In kidney transplantation, long-term allograft acceptance in cynomolgus macaques was achieved using a mixed-chimerism protocol based on the clinically available reagents, rabbit anti-thymocyte globulin (ATG), and belatacept. Here, we have
Externí odkaz:
https://doaj.org/article/bd669e56c0064385a41b8fca2c2ee16e
Publikováno v:
Transplantation. 107:827-837
The adaptive immune response leading to the rejection of allogeneic transplants is initiated and orchestrated by recipient T cells recognizing donor antigens. T-cell allorecognition is mediated via 3 distinct mechanisms: the direct pathway in which T
Autor:
Alec R. Andrews, BS, Philipp Tratnig-Frankl, MD, Corentin B. Taveau, MD, Michael M. Jonczyk, MD, Laurent A. Lantieri, MD, Mark A. Randolph, MAS, Alexandre G. Lellouch, MD, Gilles Benichou, PhD, Curtis L. Cetrulo, Jr., MD, FACS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 33-33 (2020)
Externí odkaz:
https://doaj.org/article/3cb0cce0b9b04c3c90e4599fb765aeee
Autor:
Alexandre G. Lellouch, MD, Gaelle Saviane, MSc, Laura C. Burlage, MD, Ilse M. Schol, BS, Laurent A. Lantieri, MD, Mark A. Randolph, Msc, Gilles Benichou, PhD, Curtis L. Cetrulo, Jr., MD, FACS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 7, Iss 4S, Pp 48-49 (2019)
Externí odkaz:
https://doaj.org/article/efae17cc549b48b79c09b33f57eeb7a8
Autor:
Nuala Mooney, Gilles Benichou, Bruno Gonzalez-Nolasco, Mohamed H. Babiker-Mohamed, Colleen Aslami, Aurore Prunevieille
Publikováno v:
American Journal of Transplantation
American Journal of Transplantation, Wiley, 2021, 21 (7), pp.2583-2589. ⟨10.1111/AJT.16591⟩
American Journal of Transplantation, Wiley, 2021, 21 (7), pp.2583-2589. ⟨10.1111/AJT.16591⟩
Extracellular vesicles, including exosomes, are regularly released by allogeneic cells after transplantation. Recipient antigen-presenting cells (APCs) capture these vesicles and subsequently display donor MHC molecules on their surface. Recent evide
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the adaptive inflammatory immune response leading to the rejection of allogeneic transplants. Allospecific T cells become activated through interaction of their
Externí odkaz:
https://doaj.org/article/b37343f51e5b415fa95c647c87ce9dca
Publikováno v:
American Journal of Transplantation. 20:2551-2558
Alloreactive memory T cells play a key role in transplantation by accelerating allograft rejection and preventing tolerance induction. Some studies using µMT mice, which are constitutionally devoid of B cells, showed that B cells were required for t
Autor:
Alexandre G, Lellouch, Alec R, Andrews, Gaelle, Saviane, Zhi Yang, Ng, Ilse M, Schol, Marion, Goutard, Amon-Ra, Gama, Ivy A, Rosales, Robert B, Colvin, Laurent A, Lantieri, Mark A, Randolph, Gilles, Benichou, Curtis L, Cetrulo
Publikováno v:
Frontiers in immunology. 13
Vascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is associated with significant morbidity. Induction of immune tolerance of VCAs would permit widespread