Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Gilles Gasser"'
Autor:
Keli Kuang, Chunyan Li, Fatlinda Maksut, Deepanjan Ghosh, Robin Vinck, Maolin Wang, Joël Poupon, Run Xiang, Wen Li, Fei Li, Zhu Wang, Junrong Du, Marie-Paule Teulade-Fichou, Gilles Gasser, Sophie Bombard, Tao Jia
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-21 (2024)
Abstract Background G-quadruplex DNA (G4) is a non-canonical structure forming in guanine-rich regions, which play a vital role in cancer biology and are now being acknowledged in both nuclear and mitochondrial (mt) genome. However, the impact of G4-
Externí odkaz:
https://doaj.org/article/80704c6173974d62a6f7f422874c27d1
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 78, Iss 3, Pp 313-316 (2022)
The title compound, [Co(C72H48N6)](PF6)3·H2O, crystallizes with one tripositive complex molecule, three hexafluorophosphate anions and one solvent molecule of water in the asymmetric unit. The N6 coordination set around the central CoIII atom define
Externí odkaz:
https://doaj.org/article/696b8548e432426cacd84143d122314a
Publikováno v:
CHIMIA, Vol 75, Iss 10, Pp 845-855 (2021)
Photodynamic therapy (PDT) is a remarkable alternative or complementary technique to chemotherapy, radiotherapy or immunotherapy to treat certain forms of cancer. The synergistic effect of light, photosensitizer (PS) and oxygen allows for the treatme
Externí odkaz:
https://doaj.org/article/58e8eb18845d406b9c7adc586016eefa
Autor:
Johannes Karges, Shi Kuang, Federica Maschietto, Olivier Blacque, Ilaria Ciofini, Hui Chao, Gilles Gasser
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Photosensitizers that are stable in biological conditions with absorption in the biological spectral window are needed for photodynamic therapy. Here, the authors report on the development of a Ruthenium complex for 1 and 2-photon therapy to address
Externí odkaz:
https://doaj.org/article/85e88f4cede345a9b46288b6648635b9
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it. We recently demonstrated that ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine
Externí odkaz:
https://doaj.org/article/3bf297b409854993b797ca33fdf09c20
Publikováno v:
Organic Letters. 25:624-629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1c3ebcc531b338b0c002443079c066
https://doi.org/10.1021/acs.orglett.2c04169
https://doi.org/10.1021/acs.orglett.2c04169
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1788 (2021)
Metal complexes based on transition metals have rich photochemical and photophysical properties that are derived from a variety of excited state electronic configurations triggered by visible and near-infrared light. These properties can be exploited
Externí odkaz:
https://doaj.org/article/4d47f3e6afdc4f6f9035d0ce13af5040
Autor:
Igor Pavlovic, Divyeshsinh T. Thakor, Jessica R. Vargas, Colin J. McKinlay, Sebastian Hauke, Philipp Anstaett, Rafael C. Camuña, Laurent Bigler, Gilles Gasser, Carsten Schultz, Paul A. Wender, Henning J. Jessen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Photocaged inositol-pyrophosphates offer a tool to study cellular signalling, but their challenging synthesis has precluded any biological studies so far. Here, the authors report the synthesis and cellular delivery of a photocaged analogue, and show
Externí odkaz:
https://doaj.org/article/a6bac542d07b431a964d07a618a8a4d6
Autor:
Asma Mani, Tao Feng, Albert Gandioso, Robin Vinck, Anna Notaro, Lisa Gourdon, Pierre Burckel, Bruno Saubaméa, Olivier Blacque, Kevin Cariou, Jamel‐Eddine Belgaied, Hui Chao, Gilles Gasser
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202218347⟩
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202218347⟩
International audience; Five osmium(II) polypyridyl complexes of the general formula [Os(4,7-diphenyl-1,10phenanthroline)2L] 2+ were synthesized as photosensitizers for photodynamic therapy by varying the nature of the ligand L. Thanks to the pronoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0218f1987afaf22ccfec6f8c68ccf8e8
https://doi.org/10.1002/ange.202218347
https://doi.org/10.1002/ange.202218347
Autor:
Marta Martínez-Alonso, Albert Gandioso, Chloé Thibaudeau, Xue Qin, Philippe Arnoux, Nurikamal Demeubayeva, Vincent Guérineau, Céline Frochot, Alain C. Jung, Christian Gaiddon, Gilles Gasser
Publikováno v:
ChemBioChem
ChemBioChem, 2023, ⟨10.1002/cbic.202300203⟩
ChemBioChem, 2023, ⟨10.1002/cbic.202300203⟩
International audience; A novel Ru(II) cyclometalated photosensitizer (PS), Ru-NH2, for photodynamic therapy (PDT) of formula [Ru(appy)(bphen)2]PF6 (where appy = 4-amino-2-phenylpyridine and bphen = bathophenanthroline) and its cetuximab (CTX) biocon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2aacf8b50f94408c4788e77a2351478
https://doi.org/10.1002/cbic.202300203
https://doi.org/10.1002/cbic.202300203