Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Gilles, Pagès"'
Autor:
Christopher Montemagno, Arnaud Jacquel, Charlotte Pandiani, Olivia Rastoin, Rosie Dawaliby, Thomas Schmitt, Maxence Bourgoin, Héliciane Palenzuela, Anne-Laure Rossi, Damien Ambrosetti, Jerome Durivault, Frederic Luciano, Delphine Borchiellini, Julie Le Du, Leticia Christina Pires Gonçalves, Patrick Auberger, Rachid Benhida, Lisa Kinget, Benoit Beuselinck, Cyril Ronco, Gilles Pagès, Maeva Dufies
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background In clear cell renal cell carcinoma (ccRCC), first-line treatment combines nivolumab (anti-PD-1) and ipilimumab (anti-CTLA4), yielding long-term remissions but with only a 40% success rate. Our study explored the potential of enhan
Externí odkaz:
https://doaj.org/article/2ff8f539d4e9454cb864905303b22e6e
Autor:
Christopher Montemagno, Jérôme Durivault, Cécile Gastaldi, Maeva Dufies, Valérie Vial, Xingkang He, Damien Ambrosetti, Anna Kamenskaya, Sylvie Negrier, Jean‐Christophe Bernhard, Delphine Borchiellini, Yihai Cao, Gilles Pagès
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1379-1401 (2023)
The efficacy of anti‐angiogenic treatment by targeting VEGF/VEGF receptors in metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. Discovering the reasons behind this variability could lead to the identification of rel
Externí odkaz:
https://doaj.org/article/831e3d4234ea451a9319c291c28cd020
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 385 (2024)
This review explores treating metastatic clear cell renal cell carcinoma (ccRCC) through current therapeutic modalities—anti-angiogenic therapies and immunotherapies. While these approaches represent the forefront, their limitations and variable pa
Externí odkaz:
https://doaj.org/article/6fde240d2ced4e5bb02804562660fc11
We solve a family of fractional Riccati differential equations with constant (possibly complex) coefficients. These equations arise, e.g., in fractional Heston stochastic volatility models, that have received great attention in the recent financial l
Externí odkaz:
http://arxiv.org/abs/1805.12587
Autor:
Lindsay S. Cooley, Justine Rudewicz, Wilfried Souleyreau, Andrea Emanuelli, Arturo Alvarez-Arenas, Kim Clarke, Francesco Falciani, Maeva Dufies, Diether Lambrechts, Elodie Modave, Domitille Chalopin-Fillot, Raphael Pineau, Damien Ambrosetti, Jean-Christophe Bernhard, Alain Ravaud, Sylvie Négrier, Jean-Marc Ferrero, Gilles Pagès, Sebastien Benzekry, Macha Nikolski, Andreas Bikfalvi
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Abstract Background Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated biomarkers and scarce knowledge of the biological processes occurring
Externí odkaz:
https://doaj.org/article/cee420b826cb4bfbb98850145497e573
Autor:
Maeva Dufies, Annelies Verbiest, Lindsay S. Cooley, Papa Diogop Ndiaye, Xingkang He, Nicolas Nottet, Wilfried Souleyreau, Anais Hagege, Stephanie Torrino, Julien Parola, Sandy Giuliano, Delphine Borchiellini, Renaud Schiappa, Baharia Mograbi, Jessica Zucman-Rossi, Karim Bensalah, Alain Ravaud, Patrick Auberger, Andréas Bikfalvi, Emmanuel Chamorey, Nathalie Rioux-Leclercq, Nathalie M. Mazure, Benoit Beuselinck, Yihai Cao, Jean Christophe Bernhard, Damien Ambrosetti, Gilles Pagès
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Dufies et al. find high Plk1 expression levels in aggressive clear cell renal cell carcinoma and discover that Plk1 is transcriptionally upregulated in a manner dependent on HIF-2. They also find that high Plk1 expression is correlated to a poor prog
Externí odkaz:
https://doaj.org/article/9cd5ec5c631f454a824bec657b006c8d
Autor:
Aurore Dumond, Etienne Brachet, Jérôme Durivault, Valérie Vial, Anna K. Puszko, Yves Lepelletier, Christopher Montemagno, Marina Pagnuzzi-Boncompagni, Olivier Hermine, Christiane Garbay, Nathalie Lagarde, Matthieu Montes, Luc Demange, Renaud Grépin, Gilles Pagès
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Despite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) rema
Externí odkaz:
https://doaj.org/article/4462a16912a7494aaca4c614ed37b5dd
Autor:
Manon Penco-Campillo, Clément Molina, Patricia Piris, Nouha Soufi, Manon Carré, Marina Pagnuzzi-Boncompagni, Vincent Picco, Maeva Dufies, Cyril Ronco, Rachid Benhida, Sonia Martial, Gilles Pagès
Publikováno v:
Cells, Vol 11, Iss 23, p 3933 (2022)
Medulloblastoma (MB) is the most common and aggressive paediatric brain tumour. Although the cure rate can be as high as 70%, current treatments (surgery, radio- and chemotherapy) excessively affect the patients’ quality of life. Relapses cannot be
Externí odkaz:
https://doaj.org/article/0abc9954f580428890efc79261309e44
Autor:
Christopher Montemagno, Benjamin Serrano, Jérôme Durivault, Valérie Nataf, François Mocquot, Régis Amblard, Valérie Vial, Cyril Ronco, Rachid Benhida, Maeva Dufies, Marc Faraggi, Gilles Pagès
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101098- (2021)
The chemokine receptors CXCR1/2 play a key role in the aggressiveness of several types of cancers including head and neck squamous cell carcinomas (HNSCCs). In HNSCCs, CXCR1/2 signaling promotes cell proliferation and angiogenesis leading to tumor gr
Externí odkaz:
https://doaj.org/article/0de8f2a07b134e0aa3203e7045cbdfa2
Autor:
Marie Fabre, Lou Mateo, Diana Lamaa, Stéphanie Baillif, Gilles Pagès, Luc Demange, Cyril Ronco, Rachid Benhida
Publikováno v:
Molecules, Vol 27, Iss 16, p 5089 (2022)
Age-related macular degeneration (AMD) was described for the first time in the 1840s and is currently the leading cause of blindness for patients over 65 years in Western Countries. This disease impacts the eye’s posterior segment and damages the m
Externí odkaz:
https://doaj.org/article/801ad72ccc4648a6b6ef0972087a45af