Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gilles, Dadaglio"'
Autor:
Antoine Domenger, Caroline Choisy, Ludivine Baron, Véronique Mayau, Emeline Perthame, Ludovic Deriano, Bertrand Arnulf, Jean‐Christophe Bories, Gilles Dadaglio, Caroline Demangel
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp 1-17 (2022)
Abstract Multiple myeloma (MM) is an incurable malignancy characterized by the uncontrolled expansion of plasma cells in the bone marrow. While proteasome inhibitors like bortezomib efficiently halt MM progression, drug resistance inevitably develop,
Externí odkaz:
https://doaj.org/article/22da9be175514a33a0ab22c7d255aaf8
Autor:
Antoine Domenger, Daniela Ricci, Véronique Mayau, Laleh Majlessi, Christophe Marcireau, Gilles Dadaglio, Caroline Demangel
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Multiple Myeloma (MM) is an incurable neoplasm of mature B cells and the second most prevalent hematological malignancy worldwide. While combinations of proteasome inhibitors like bortezomib (Bz) and immunomodulators (IMiDs) like lenalinomide (Len) a
Externí odkaz:
https://doaj.org/article/4bf93cccf969455d81bfe0750633a531
Autor:
Gilles Dadaglio, Catherine Fayolle, Marine Oberkampf, Alexandre Tang, Francesc Rudilla, Isabelle Couillin, Eirik A. Torheim, Pierre Rosenbaum, Claude Leclerc
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Antitumor immunity is mediated by Th1 CD4+ and CD8+ T lymphocytes, which induce tumor-specific cytolysis, whereas Th17 CD4+ T cells have been described to promote tumor growth. Here, we explored the influence of IL-17 on the ability of therapeutic va
Externí odkaz:
https://doaj.org/article/5233de5bf6bf40c49d8d32de56bb46e2
Autor:
Marine Oberkampf, Camille Guillerey, Juliette Mouriès, Pierre Rosenbaum, Catherine Fayolle, Alexandre Bobard, Ariel Savina, Eric Ogier-Denis, Jost Enninga, Sebastian Amigorena, Claude Leclerc, Gilles Dadaglio
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cross-presentation allows exogenous antigens to be presented by the major histocompatibility I pathway. Here the authors show that the inducible cross-presentation by plasmacytoid dendritic cells is modulated by mitochondria-originated reactive oxyge
Externí odkaz:
https://doaj.org/article/10dc91008a66480690b43c080dae3057
Autor:
Céline Cousin, Marine Oberkampf, Tristan Felix, Pierre Rosenbaum, Robert Weil, Sylvie Fabrega, Valeria Morante, Donatella Negri, Andrea Cara, Gilles Dadaglio, Claude Leclerc
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1242-1257.e7 (2019)
Summary: Lentiviruses are among the most promising viral vectors for in vivo gene delivery. To overcome the risk of insertional mutagenesis, integrase-deficient lentiviral vectors (IDLVs) have been developed. We show here that strong and persistent s
Externí odkaz:
https://doaj.org/article/066c2f9a277e49c2bf270907fe48d352
Autor:
Claude Leclerc, Gilles Dadaglio, Camille Guillerey, Pierre Rosenbaum, Catherine Fayolle, Marine Oberkampf, Mariana Terra
A growing number of observations has suggested that plasmacytoid dendritic cells (pDC) play a critical role in tumor biology. In patients, infiltration of tumors by pDCs generally correlates with a poor prognosis, suggesting that pDCs may play an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708e4739b2c88e8a248c444256e41b08
https://doi.org/10.1158/0008-5472.c.6510660.v1
https://doi.org/10.1158/0008-5472.c.6510660.v1
Autor:
Claude Leclerc, Gilles Dadaglio, Camille Guillerey, Pierre Rosenbaum, Catherine Fayolle, Marine Oberkampf, Mariana Terra
Supplementary Figures S1 through S9. (1) Supplementary Figure S1: Phenotypical characterization of pDCs in the spleen of TC-1 and B16-OVA tumor-bearing mice. (2) Supplementary Figure S2. Purification of pDCs and gene family analysis. (3) Supplementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfb54fb17db3f2c576f333566c186ef
https://doi.org/10.1158/0008-5472.22420470.v1
https://doi.org/10.1158/0008-5472.22420470.v1
Autor:
Antoine Domenger, Daniela Ricci, Véronique Mayau, Laleh Majlessi, Christophe Marcireau, Gilles Dadaglio, Caroline Demangel
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, 2023, 13, pp.1110916. ⟨10.3389/fonc.2023.1110916⟩
Frontiers in Oncology, 2023, 13, pp.1110916. ⟨10.3389/fonc.2023.1110916⟩
Purpose Multiple Myeloma (MM) is an incurable neoplasm of mature B cells and the second most prevalent hematological malignancy worldwide. While combinations of proteasome inhibitors like bortezomib (Bz) and immunomodulators (IMIDs) like lenalinomide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cdd2e059fce3d942038201661495c4
https://doi.org/10.21203/rs.3.rs-2237633/v1
https://doi.org/10.21203/rs.3.rs-2237633/v1
Autor:
Bertrand Arnulf, Gilles Dadaglio, Véronique Mayau, Antoine Domenger, Ludivine Baron, Jean-Christophe Bories, Caroline Choisy, Ludovic Deriano, Caroline Demangel
Multiple Myeloma (MM) is an incurable malignancy characterized by the uncontrolled expansion of plasma cells in the bone marrow. While proteasome inhibitors like bortezomib efficiently halt MM progression, drug resistance or toxicity inevitably devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9c971aa5eb30308bf857ce9162bcb5c
https://doi.org/10.1101/2021.09.05.459026
https://doi.org/10.1101/2021.09.05.459026
Autor:
Nada Chaoul, Gilles Dadaglio
Publikováno v:
Methods in molecular biology (Clifton, N.J.)
Cytotoxic T-Cells: methods and protocols
Margherita Gigante; Elena Ranieri. Cytotoxic T-Cells: methods and protocols, 2325, Sringer, pp.55-64, 2021, Methods in Molecular Biology, 978-1-0716-1507-2 (e-book). ⟨10.1007/978-1-0716-1507-2_4⟩
Methods in Molecular Biology ISBN: 9781071615065
Methods in Molecular Biology
Cytotoxic T-Cells: methods and protocols
Margherita Gigante; Elena Ranieri. Cytotoxic T-Cells: methods and protocols, 2325, Sringer, pp.55-64, 2021, Methods in Molecular Biology, 978-1-0716-1507-2 (e-book). ⟨10.1007/978-1-0716-1507-2_4⟩
Methods in Molecular Biology ISBN: 9781071615065
Methods in Molecular Biology
International audience; The in vivo killing assay allows the quantification of the antigen-specific killing capacity of Cytotoxic CD8+ T Lymphocytes (CTLs) in mice. CTLs are indeed known for the lysis of cells expressing foreign or modified antigen p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d229253f9bede3646abb616ae9706fe9
https://hal-pasteur.archives-ouvertes.fr/pasteur-03261883
https://hal-pasteur.archives-ouvertes.fr/pasteur-03261883