Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gilla, Goverdhan"'
Autor:
Mittapalli, Sudhir, Doke, Suresh, Sawant, Pramod, Nagaprasada Rao, L., Ghosh, Santosh, Gilla, Goverdhan, Nambiar, Sudhir
Publikováno v:
In Journal of Molecular Structure 5 March 2020 1203
Publikováno v:
Journal of Saudi Chemical Society, Vol 18, Iss 2, Pp 129-138 (2014)
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, eight process related impurities were observed at a level of 0.1–0.15 area percent
Externí odkaz:
https://doaj.org/article/bdd576b94598408b882da89bc6f94515
Publikováno v:
Journal of Saudi Chemical Society, Vol 18, Iss 2, Pp 129-138 (2014)
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, eight process related impurities were observed at a level of 0.1–0.15 area percent
Synthesis and characterization of related substances and metabolite of tadalafil, a PDE-5 inhibitor.
Autor:
Gilla, Goverdhan1,2 goverdhan_75@yahoo.com, Anumula, Raghupathi Reddy1, Aalla, Sampath1, Vurimidi, Himabindu2, Ghanta, Mahesh Reddy3
Publikováno v:
Organic Communications. 2013, Vol. 6 Issue 1, p12-22. 11p.
Autor:
G. Venkateswarlu, Gilla Goverdhan, R. Vijaya Anand, K. Srihari Babu, P. Srinivas, M. Raghavendar Rao, P. Pratap Reddy
Publikováno v:
Synthetic Communications. 43:1751-1758
Valganciclovir hydrochloride (1) is used for the treatment of cytomegalovirus (CMV) retinitis in patients with weakened immune systems. Valganciclovir hydrochloride is a hydrochloride salt of L-valyl ester of ganciclovir (2) that exists as a mixture
Autor:
Gilla Goverdhan, Anumula Raghupathi Reddy, N. Rama Krishna Reddy, Kurella Srinivas, Vurimidi Himabindu, Ghanta Mahesh Reddy
Publikováno v:
Organic Communications, Vol 5, Iss 1, Pp 27-41 (2012)
Design, synthesis and characterization of four novel series of Zafirlukast analogs are described. The modifications are substitution on indole nitrogen, C-5 position of indole moiety and amide nitrogen of zafirlukast.
Autor:
Aalla Sampath, Gilla Goverdhan, Rakeshwar Bandichhor, Anumula Raghupathi Reddy, Padi Pratap Reddy, Khagga Mukkanti
Publikováno v:
Synthetic Communications. 42:639-649
A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in situ–generated nitrile oxide derivatives.
Autor:
Gilla Goverdhan, Vurimidi Himabindu, K. Srinivas, Anumula Raghupathi Reddy, Ghanta Mahesh Reddy
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 49:895-900
Zafirlukast is a drug in the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, five unknown impurities were detected at levels of below 0.10% (ranging from 0.05 to 0.15%) in reverse phase gradient high pe
Autor:
Anumula Raghupathi Reddy, Gilla Goverdhan, Ghanta Mahesh Reddy, Aalla Sampath, K. Srinivas, Vurimidi Himabindu
Publikováno v:
Organic Process Research & Development. 13:67-72
An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and scale-up-related issues.
Autor:
Kagga Mukkanti, Bojja Yakambaram, Alla Sampath, Gilla Goverdhan, Padi Pratap Reddy, Anumula Raghupathi Reddy
Publikováno v:
Organic Process Research & Development. 13:98-101
An improved, scalable and commercially viable process is developed for an active pharmaceutical ingredient, celecoxib.