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Autor:
Gileno Dos Santos de Sousa, Adriani L. Felix, Murilo M. Pedrote, Mayra A. Marques, Guilherme Oliveira, Michelle F. Mota, Fernando P. Almeida, Jerson L. Silva, Benjamin Jakobus, Filipe Pereira da Costa, Giulia D. S. Ferretti, Yulli M. Passos, Elaine C Petronilho, Yraima Cordeiro, Tuane C. R. G. Vieira
Publikováno v:
Chemical Science
Mutant p53 tends to form aggregates with amyloid properties, especially amyloid oligomers inside the nucleus, which are believed to cause oncogenic gain-of-function (GoF). The mechanism of the formation of the aggregates in the nucleus remains uncert