Profiling the endothelial translatome in vivo using ‘AngioTag’ zebrafish

Autor: Brant M. Weinstein, Adam R. Davis, Andreas D. Baxevanis, Aloi N, Lisa M Price, Gildea De, Monzo K, Amber N. Stratman, Van N. Pham, Martin L. Miller

SUMMARYVascular endothelial cellsin vivoare exquisitely regulated by their local environment, which is absent or disrupted when using methods such as FACS orin vitrocell culture to study native signaling pathways. Here, we profile the gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde6d9f229138fb3f62381279220c4d3

GeneLink: a database to facilitate genetic studies of complex traits

Autor: Wolfsberg Tyra G, Trout Ken, Ibay Grace, Freas-Lutz Diana, Klein Alison P, Jones Mary, Duggal Priya, Umayam Lowell, Gildea Derek, Masiello Anthony, Gillanders Elizabeth M, Trent Jeffrey M, Bailey-Wilson Joan E, Baxevanis Andreas D

Publikováno v: BMC Genomics, Vol 5, Iss 1, p 81 (2004)

Abstract Background In contrast to gene-mapping studies of simple Mendelian disorders, genetic analyses of complex traits are far more challenging, and high quality data management systems are often critical to the success of these projects. To minim

Externí odkaz: https://doaj.org/article/82a53057e9f04a0bb8f0e14ba604c838

Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder.

Autor: Sudre G; Social and Behavioral Research Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA., Gildea DE; Computational and Statistical Genomics Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA., Shastri GG; Office of the Scientific Director, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA., Sharp W; Office of the Scientific Director, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA., Jung B; Social and Behavioral Research Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA., Xu Q; Human Brain Collection Core, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA., Auluck PK; Human Brain Collection Core, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA., Elnitski L; Translational and Functional Genomics Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA., Baxevanis AD; Computational and Statistical Genomics Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA., Marenco S; Human Brain Collection Core, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA., Shaw P; Social and Behavioral Research Branch, Division of Intramural Research, National Human Genome Research Institute, NIH, Bethesda, MD, 20892, USA. shawp@mail.nih.gov.; Office of the Scientific Director, Division of Intramural Research, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA. shawp@mail.nih.gov.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Feb; Vol. 28 (2), pp. 792-800. Date of Electronic Publication: 2022 Nov 16.

MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells.

Autor: Fufa TD; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Baxter LL; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Wedel JC; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Gildea DE; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Loftus SK; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Pavan WJ; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA. bpavan@mail.nih.gov.

Publikováno v: Epigenetics & chromatin [Epigenetics Chromatin] 2019 Aug 09; Vol. 12 (1), pp. 50. Date of Electronic Publication: 2019 Aug 09.

A direct link between MITF, innate immunity, and hair graying.

Autor: Harris ML; Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Fufa TD; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Palmer JW; Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Joshi SS; Department of Biochemistry and Molecular Biology, University of Maryland, School of Medicine, Baltimore, Maryland, United States of America., Larson DM; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Incao A; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Gildea DE; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Trivedi NS; Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Lee AN; Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Day CP; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Michael HT; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Hornyak TJ; Department of Biochemistry and Molecular Biology, University of Maryland, School of Medicine, Baltimore, Maryland, United States of America.; Research & Development Service, VA Maryland Health Care System, Baltimore, Maryland, United States of America., Merlino G; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Pavan WJ; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

Publikováno v: PLoS biology [PLoS Biol] 2018 May 03; Vol. 16 (5), pp. e2003648. Date of Electronic Publication: 2018 May 03 (Print Publication: 2018).