Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Gildas Loussouarn"'
Autor:
Barbara B. R. Oliveira‐Mendes, Malak Alameh, Jérôme Montnach, Béatrice Ollivier, Solène Gibaud, Sylvain Feliciangeli, Florian Lesage, Flavien Charpentier, Gildas Loussouarn, Michel De Waard, Isabelle Baró
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/40978472905f4000b05d8795faddb34a
A need for exhaustive and standardized characterization of ion channels activity. The case of KV11.1
Autor:
Malak Alameh, Barbara Ribeiro Oliveira-Mendes, Florence Kyndt, Jordan Rivron, Isabelle Denjoy, Florian Lesage, Jean-Jacques Schott, Michel De Waard, Gildas Loussouarn
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
hERG, the pore-forming subunit of the rapid component of the delayed rectifier K+ current, plays a key role in ventricular repolarization. Mutations in the KCNH2 gene encoding hERG are associated with several cardiac rhythmic disorders, mainly the Lo
Externí odkaz:
https://doaj.org/article/71b00d18ad514452996f646c5d8d8348
Autor:
Martial Caillaud, Morgane E. Le Dréan, Adrien De-Guilhem-de-Lataillade, Catherine Le Berre-Scoul, Jérôme Montnach, Steven Nedellec, Gildas Loussouarn, Vincent Paillé, Michel Neunlist, Hélène Boudin
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
The enteric nervous system (ENS) is the intrinsic nervous system that innervates the entire digestive tract and regulates major digestive functions. Recent evidence has shown that functions of the ENS critically rely on enteric neuronal connectivity;
Externí odkaz:
https://doaj.org/article/56df6005729c43a6a6e406303b8f0fde
Autor:
Barbara B. R. Oliveira-Mendes, Malak Alameh, Béatrice Ollivier, Jérôme Montnach, Nicolas Bidère, Frédérique Souazé, Nicolas Escriou, Flavien Charpentier, Isabelle Baró, Michel De Waard, Gildas Loussouarn
Publikováno v:
Cells, Vol 12, Iss 11, p 1474 (2023)
Controversial reports have suggested that SARS-CoV E and 3a proteins are plasma membrane viroporins. Here, we aimed at better characterizing the cellular responses induced by these proteins. First, we show that expression of SARS-CoV-2 E or 3a protei
Externí odkaz:
https://doaj.org/article/633e57adb491400ea4f4c0e3ef2f4bb4
Autor:
Jérôme Montnach, Maxime Lorenzini, Adrien Lesage, Isabelle Simon, Sébastien Nicolas, Eléonore Moreau, Céline Marionneau, Isabelle Baró, Michel De Waard, Gildas Loussouarn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The patch-clamp technique and more recently the high throughput patch-clamp technique have contributed to major advances in the characterization of ion channels. However, the whole-cell voltage-clamp technique presents certain limits that ne
Externí odkaz:
https://doaj.org/article/fc995879801249e6af526213e9a3435d
Autor:
Olfat A. Malak, Fayal Abderemane-Ali, Yue Wei, Fabien C. Coyan, Gilyane Pontus, David Shaya, Céline Marionneau, Gildas Loussouarn
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Prokaryotic NaV channels are tetramers and eukaryotic NaV channels consist of a single subunit containing four domains. Each monomer/domain contains six transmembrane segments (S1-S6), S1-S4 being the voltage-sensor domain and S5-S6 the pore
Externí odkaz:
https://doaj.org/article/c55713584dc441e5873be97cf8de9611
Autor:
Barbara Oliveira‐Mendes, Sylvain Feliciangeli, Mélissa Ménard, Frank Chatelain, Malak Alameh, Jérôme Montnach, Sébastien Nicolas, Béatrice Ollivier, Julien Barc, Isabelle Baró, Jean‐Jacques Schott, Vincent Probst, Florence Kyndt, Isabelle Denjoy, Florian Lesage, Gildas Loussouarn, Michel De Waard
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Background and aims Mutations in KCNH2 cause long or short QT syndromes (LQTS or SQTS) predisposing to life‐threatening arrhythmias. Over 1000 hERG variants have been described by clinicians, but most remain to be characterised. The object
Externí odkaz:
https://doaj.org/article/acbf1713166b446c8093329363ed25ac
Autor:
Gildas Loussouarn, Mounir Tarek
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/9a151b273d9443d5ac9ce21bfec942f8
Autor:
Zeina R. Al Sayed, Mariam Jouni, Jean‐Baptiste Gourraud, Nadjet Belbachir, Julien Barc, Aurore Girardeau, Virginie Forest, Aude Derevier, Anne Gaignerie, Caroline Chariau, Bastien Cimarosti, Robin Canac, Pierre Olchesqui, Eric Charpentier, Jean‐Jacques Schott, Richard Redon, Isabelle Baró, Vincent Probst, Flavien Charpentier, Gildas Loussouarn, Kazem Zibara, Guillaume Lamirault, Patricia Lemarchand, Nathalie Gaborit
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/2317e090f55f4c2ab06747c2064a68e2
Autor:
Maria Karlova, Denis V. Abramochkin, Ksenia B. Pustovit, Tatiana Nesterova, Valery Novoseletsky, Gildas Loussouarn, Elena Zaklyazminskaya, Olga S. Sokolova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7953 (2022)
We identified a single nucleotide variation (SNV) (c.1264A > G) in the KCNQ1 gene in a 5-year-old boy who presented with a prolonged QT interval. His elder brother and mother, but not sister and father, also had this mutation. This missense mutation
Externí odkaz:
https://doaj.org/article/bafdc579680b46fbba31c5977456a600