Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gilda Stefanelli"'
Autor:
Gurdeep Singh, Gilda Stefanelli, Klotilda Narkaj, Mark A. Brimble, Samantha D. Creighton, Timothy A. B. McLean, Meaghan Hall, Krista A. Mitchnick, Jacqueline Zakaria, Thanh Phung, Anas Reda, Amanda M. Leonetti, Ashley Monks, Lara Ianov, Boyer D. Winters, Brandon J. Walters, Andrew M. Davidoff, Jennifer A. Mitchell, Iva B. Zovkic
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The structurally-unique histone variant, mH2A1, influences learning and memory in mice to a greater extent than a similar variant, mH2A2.
Externí odkaz:
https://doaj.org/article/d840a5d938684f1fae4467b25c62e8a3
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 5, p 108 (2023)
Neurodevelopment is a highly regulated process that relies on the precise regulation of gene expression. Numerous epigenetic mechanisms contribute and cooperate to ensure the proper execution of developmental gene expression programs. Indeed, disrupt
Externí odkaz:
https://doaj.org/article/5c7244eee0e241499a2dd6f04dd15d45
Autor:
Gurdeep Singh, Gilda Stefanelli, Klotilda Narkaj, Mark A. Brimble, Samantha D. Creighton, Timothy A. B. McLean, Meaghan Hall, Krista A. Mitchnick, Jacqueline Zakaria, Thanh Phung, Anas Reda, Amanda M. Leonetti, Ashley Monks, Lara Ianov, Boyer D. Winters, Brandon J. Walters, Andrew M. Davidoff, Jennifer A. Mitchell, Iva B. Zovkic
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/a2cbb085173249b3b824b77e9b19d7bc
Autor:
Gilda Stefanelli, Anna Gandaglia, Mario Costa, Manjinder S. Cheema, Daniele Di Marino, Isabella Barbiero, Charlotte Kilstrup-Nielsen, Juan Ausió, Nicoletta Landsberger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a7e47d1e73524e08906128d0d9449ef5
Autor:
Gilda Stefanelli, Amber B. Azam, Brandon J. Walters, Mark A. Brimble, Caroline P. Gettens, Pascale Bouchard-Cannon, Hai-Ying M. Cheng, Andrew M. Davidoff, Klotilda Narkaj, Jeremy J. Day, Andrew J. Kennedy, Iva B. Zovkic
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1124-1131 (2018)
Summary: Histone variants were recently discovered to regulate neural plasticity, with H2A.Z emerging as a memory suppressor. Using whole-genome sequencing of the mouse hippocampus, we show that basal H2A.Z occupancy is positively associated with ste
Externí odkaz:
https://doaj.org/article/9c12da0205304d89b9ae92c1b0d9e7ab
Autor:
Katrina V. Good, Alexia Martínez de Paz, Monica Tyagi, Manjinder S. Cheema, Anita A. Thambirajah, Taylor L. Gretzinger, Gilda Stefanelli, Robert L. Chow, Oliver Krupke, Michael Hendzel, Kristal Missiaen, Alan Underhill, Nicoletta Landsberger, Juan Ausió
Publikováno v:
Epigenetics, Vol 12, Iss 11, Pp 934-944 (2017)
MeCP2 binds to methylated DNA in a chromatin context and has an important role in cancer and brain development and function. Histone deacetylase (HDAC) inhibitors are currently being used to palliate many cancer and neurological disorders. Yet, the m
Externí odkaz:
https://doaj.org/article/1a4ada9531774b788374f89e3cf3fbfa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6918 (2020)
The neuronal epigenome is highly sensitive to external events and its function is vital for producing stable behavioral outcomes, such as the formation of long-lasting memories. The importance of epigenetic regulation in memory is now well establishe
Externí odkaz:
https://doaj.org/article/5c443665fc2b4741a730b9ec1210c8f1
Autor:
Manjinder S. Cheema, Katrina V. Good, Bohyun Kim, Heddy Soufari, Connor O’Sullivan, Melissa E. Freeman, Gilda Stefanelli, Ciro Rivera Casas, Kristine E. Zengeler, Andrew J. Kennedy, Jose Maria Eirin Lopez, Perry L. Howard, Iva B. Zovkic, Jeffrey Shabanowitz, Deanna D. Dryhurst, Donald F. Hunt, Cameron D. Mackereth, Juan Ausió
Publikováno v:
Cells, Vol 9, Iss 5, p 1167 (2020)
The replication independent (RI) histone H2A.Z is one of the more extensively studied variant members of the core histone H2A family, which consists of many replication dependent (RD) members. The protein has been shown to be indispensable for surviv
Externí odkaz:
https://doaj.org/article/517b3db1d9174cdc83b82142f8ac91b1
Autor:
Isabella Barbiero, Daniele Di Marino, Charlotte Kilstrup-Nielsen, Nicoletta Landsberger, Mario Costa, Anna Gandaglia, Manjinder S. Cheema, Gilda Stefanelli, Juan Ausió
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Anna Gandaglia, Anna Bergo, Lara Pizzamiglio, Flavia Antonucci, Marco Cicerone, Michela Palmieri, Veronica Bianchi, Daniele Di Marino, Charlotte Kilstrup-Nielsen, Sara Carli, Francesco Bedogni, Ilda D'Annessa, Gilda Stefanelli, Elena Brivio, Patrizia D'Adamo, Nicoletta Landsberger, Angelisa Frasca, Barbara Leva, Chiara M Cattaneo
Publikováno v:
Molecular Neurobiology. 56:4838-4854
MeCP2 is a fundamental protein associated with several neurological disorders, including Rett syndrome. It is considered a multifunctional factor with a prominent role in regulating chromatin structure; however, a full comprehension of the consequenc