Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gilda P. Womble"'
Publikováno v:
Epilepsy & Behavior. 5:31-36
This open-label, 6-year continuation study of several short-term clinical trials was conducted to assess the long-term tolerability and efficacy of lamotrigine when used as adjunctive therapy or monotherapy for partial seizures in adult patients (> o
Autor:
Gilda P. Womble, E. J. Casale, Gregory L. Holmes, Chao Chen, P. Manasco, L. M. Frank, T. Enlow, S. Concannon
Publikováno v:
Epilepsia. 40:973-979
Summary: Purpose: To investigate whether lamotrigine (LTG) monotherapy is effective and safe for newly diagnosed typical absence seizures in children and adolescents (aged 3–15 years, n = 45). Methods: A “responder-enriched” study design was us
Autor:
Eugène Cox, Thaddeus H. Grasela, Jill Fiedler-Kelly, Chao Chen, Marcus E. Risner, Gilda P. Womble
Publikováno v:
Journal of clinical pharmacology. 39(4)
Plasma concentrations of lamotrigine, an antiepileptic drug obtained in three adult controlled clinical trials conducted in the United States were pooled and analyzed using NONMEM, a population pharmacokinetic computer program, to facilitate developm
Autor:
R F Leroy, Gilda P. Womble, J J Zielinski, John A. Messenheimer, John M. Pellock, R. E. Ramsay, Richard H. Mattson, L. J. Willmore, Marcus E. Risner, A M Valakas
Publikováno v:
Epilepsia. 35(1)
The efficacy and safety of lamotrigine (LTG), a new antiepileptic drug (AED), were evaluated in a multicenter, randomized, double-blind, placebo-controlled, cross-over study of 98 patients with refractory partial seizures. Each treatment period laste