Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gilberto Valdes-Garcia"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Computational methods to study protein structural dynamics are a powerful tool in life sciences but are computationally expensive. Here, the authors show that machine learning can be used to efficiently generate protein conformational ensembles and t
Externí odkaz:
https://doaj.org/article/b400ceceeef64e98a4a12bc0b6ba15b8
Publikováno v:
Journal of chemical theory and computation.
Biomolecular condensation, especially liquid-liquid phase separation, is an important physical process with relevance for a number of different aspects of biological functions. Key questions of what drives such condensation, especially in terms of mo
Autor:
Gilberto Valdes-Garcia, Kasun Gamage, Casey Smith, Karina Martirosova, Michael Feig, Lisa J. Lapidus
Understanding the thermodynamics that drives liquid-liquid phase separation (LLPS) is quite important given the many numbers of diverse biomolecular systems undergoing this phenomenon. Regardless of the diversity, the processes underlying the formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d2fd472bf65d88ac5397f7c8fee911
https://doi.org/10.1101/2022.11.21.517354
https://doi.org/10.1101/2022.11.21.517354
Publikováno v:
The journal of physical chemistry letters. 13(43)
Transient protein-protein interactions occur frequently under the crowded conditions encountered in biological environments, yet they remain poorly understood. Here, tryptophan-cysteine quenching is introduced as an experimental approach that is idea
Autor:
Gilberto Valdes-Garcia, Kasun Gamage, Casey Smith, Karina Martirosova, Michael Feig, Lisa J. Lapidus
Publikováno v:
Cell Reports Physical Science. 4:101415
Autor:
Angel E. Pelaez-Aguilar, Gilberto Valdés-García, Leidys French-Pacheco, Nina Pastor, Carlos Amero, Lina Rivillas-Acevedo
Publikováno v:
ACS Omega, Vol 5, Iss 13, Pp 7085-7095 (2020)
Externí odkaz:
https://doaj.org/article/8460e10dfd674d7ca0c34a3f85b386fe
Autor:
Roberto Maya-Martinez, Leidys French-Pacheco, Gilberto Valdés-García, Nina Pastor, Carlos Amero
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4078 (2019)
Light-chain amyloidosis (AL) is the most common systemic amyloidosis and is caused by the deposition of mainly insoluble immunoglobulin light chain amyloid fibrils in multiple organs, causing organ failure and eventually death. The germ-line λ6a has
Externí odkaz:
https://doaj.org/article/80803dbb0c2b4efc92581191baef6543